Can a common blood pressure drug help CF lungs clear mucus?

NCT ID NCT03435939

First seen Nov 01, 2025 · Last updated Apr 28, 2026 · Updated 29 times

Summary

This study tests whether losartan, a blood pressure medication, can help clear mucus from the lungs of people with cystic fibrosis (CF) who cannot take current CFTR-targeted therapies. Sixteen adults with mild to moderate lung disease will take losartan for over 12 weeks. The goal is to see if it improves lung function and reduces inflammation.

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Contacts and locations

Locations

  • University of Kansas Medical Center

    Kansas City, Kansas, 66160, United States

Conditions

Explore the condition pages connected to this study.