University Of Kansas Medical Center

This study aimed to test if rituximab, a drug that targets immune B cells, could help control Chronic Inflammatory Demyelinating Polyneuropathy (CIDP), a disorder where the immune system attacks the nerves. Researchers wanted to see if the drug could allow some patients to stop t…

This study compares two telemedicine approaches to help rural residents with obesity manage their weight over 18 months. One approach uses quarterly doctor visits, while the other adds group lifestyle coaching sessions via Zoom. Researchers want to see which method helps people l…

This study is testing a drug called sacituzumab govitecan in people with advanced bile duct cancer (cholangiocarcinoma) that has come back or spread after at least one prior treatment. The drug is designed to target cancer cells specifically, delivering a toxic agent directly to …

This study is testing if drinking a special carbohydrate drink before a long urologic surgery helps control blood sugar levels and leads to better recovery. It will compare a specialized sports drink to a standard one in 30 adults having surgery lasting over 4 hours. Researchers …

This study is testing whether combining two drugs, regorafenib and durvalumab, can help control advanced bile duct cancer that has continued to grow after standard chemotherapy. It is for up to 40 patients whose cancer has worsened despite one prior treatment. The main goals are …

This small, early-stage study is testing whether losartan, a common blood pressure medication, can help improve mucus clearance in adults with cystic fibrosis who cannot take newer, targeted CFTR therapies. Researchers want to see if reducing inflammation with losartan for 14 wee…

This study is testing a new approach to help rural families manage weight. It compares two versions of a televideo program: one where parents get coaching first, then join sessions with their child, versus a program where parents and children attend together from the start. The g…

This study is testing whether sirolimus, a medication used in organ transplants, can slow down or stop the progression of inclusion body myositis (IBM), a rare muscle-wasting disease. It will involve 140 adults with IBM who will take the drug or a placebo for 84 weeks to see if i…

This early-stage study is testing the safety of combining two drugs, alpelisib and sacituzumab govitecan, for people with advanced HER2-negative breast cancer that has spread or returned. The main goal is to find the safest and most effective dose of this combination for use in f…

This study is testing a web-based tracking system designed to help more women in Kenya get screened for cervical cancer and receive proper follow-up care if needed. It involves 10 hospitals and aims to see if the system improves how often women complete screening and get the righ…

This study tests a health education program designed for women who are leaving jail. The program aims to improve their knowledge and actions related to preventing cervical cancer, breast cancer, sexually transmitted diseases, and unintended pregnancy. Researchers are comparing th…

This study is testing whether a combination of two hormone medications (bazedoxifene and conjugated estrogens) can reduce markers of breast cancer risk in women who are at increased risk and experiencing menopausal hot flashes. About 120 women will be randomly assigned to take th…

This study is testing if adding a special type of electrical muscle stimulation to standard physical therapy helps people recover muscle strength better after ACL knee surgery. Researchers will compare muscle strength and symmetry between the injured and healthy leg in about 25 p…

This study is comparing two procedures that target nerves to relieve chronic low back pain. It tests a newer method that freezes nerves (iovera°) against the standard method that uses heat to burn them (radiofrequency ablation). Researchers will enroll 30 people and track their p…

This study aimed to find out if removing a patient's urinary catheter sooner after minimally invasive back surgery helps them get up and walk faster. It planned to compare 'early removal' to the usual 'delayed removal' timing. The goal was to see if walking sooner could lead to a…

This study aims to understand how different types of exercise affect memory and brain health in older adults. Researchers will enroll 280 healthy adults aged 65-80 and assign them to different 26-week exercise programs, including aerobic training, strength training, or a combinat…

This study aims to understand if lowering blood pressure can help manage chronic pain. It involves 36 adults who have both chronic back pain and high blood pressure, and who already have a permanent spinal cord stimulator. Participants will take a standard blood pressure pill (a …

This study aims to understand why some people taking cholesterol-lowering statin drugs don't improve their fitness as much from exercise as expected. Researchers will have a small group of statin users complete a 6-week supervised exercise program. They will measure fitness befor…

This study is checking if the weight loss medication tirzepatide changes markers in the body that are linked to breast cancer risk. It involves 20 women with obesity who are already planning to take tirzepatide. Researchers will measure things in their blood, breast tissue, and s…