Could a transplant drug slow a rare muscle disease?
NCT ID NCT04789070
First seen Jan 19, 2026 · Last updated May 15, 2026 · Updated 15 times
Summary
This phase 3 trial tests sirolimus, a drug used in organ transplants, to see if it can slow or stop muscle decline in people with inclusion body myositis (IBM), a rare muscle disease. About 140 adults aged 45 and older who can walk at least 200 meters are taking part. The study measures changes in daily function and walking ability over 84 weeks.
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This is a summary of
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Austin Health
Melbourne, Victoria, Australia
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Concord Repatriation Hospital
Sydney, New South Wales, Australia
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Johns Hopkins University
Baltimore, Maryland, 21218, United States
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Leiden University Medical Center
Leiden, Netherlands
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Perron Institute
Perth, Washington, Australia
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Royal Adelaide Hospital
Adelaide, South Australia, Australia
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Royal Brisbane and Women's Hospital
Brisbane, Queensland, Australia
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Royal Northshore Hospital
Sydney, New South Wales, Australia
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St Vincent's Hospital
Melbourne, Victoria, Australia
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University of Kansas Medical Center
Kansas City, Kansas, 66160, United States
Conditions
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