Could a common diabetes drug help lungs in cystic fibrosis?

NCT ID NCT04530383

First seen Sep 30, 2025 · Last updated Apr 30, 2026 · Updated 28 times

Summary

This study tests whether metformin, a standard diabetes medication, can improve how cells in the airways move salt and water in adults with cystic fibrosis-related diabetes (CFRD). Participants must already be taking a CFTR modulator drug. The trial will measure changes in gene activity and ion channel function using nasal cell samples. It aims to find a new way to ease lung problems in this specific group.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Kansas Medical Center

    RECRUITING

    Kansas City, Kansas, 66160, United States

    Contact

    Contact Phone: •••-•••-••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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