Blood pressure drug may help preserve insulin in cystic fibrosis
NCT ID NCT07688070
First seen Jul 07, 2026 · Last updated Jul 10, 2026 · Updated 3 times
Summary
This study tests whether verapamil, a common blood pressure medication, can help protect insulin-producing cells in people with cystic fibrosis who have early blood sugar problems or diabetes. Participants take verapamil for several weeks, and researchers measure changes in insulin and C-peptide levels after a meal. The goal is to see if this drug can slow or improve glucose control in this population.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- verapamil (a blood pressure medication)
- What this could lead to
- If it works, this could point toward a new way to preserve insulin production and manage blood sugar in people with cystic fibrosis.
- What could go wrong
- This is a small, early pilot study without a placebo group, so results may not be conclusive. Verapamil can cause side effects like low blood pressure or constipation.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Diabetes Research Center, Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Rhode Island Hospital
Providence, Rhode Island, 02903, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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