Melanoma combo therapy study halted early

NCT ID NCT04695977

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested a new combination treatment for people with advanced melanoma that cannot be removed by surgery or has spread. The combination included an experimental drug injected into tumors (CMP-001) plus an immunotherapy given through a vein (nivolumab). It was compared to nivolumab alone. The study was terminated early after enrolling only 20 participants, so results are limited.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary โ€” we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

melanoma metastatic melanoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Atlantic Health

    Morristown, New Jersey, 07960, United States

  • California Cancer Associates for Research & Excellence, Inc.

    San Marcos, California, 92069, United States

  • Cleveland Clinic

    Weston, Florida, 33331, United States

  • Duke University Cancer Institute

    Durham, North Carolina, 27710, United States

  • Hartford Healthcare

    Hartford, Connecticut, 06106, United States

  • Mayo Clinic Arizona

    Phoenix, Arizona, 85054, United States

  • Moores Cancer Center at UC San Diego Health

    La Jolla, California, 92093, United States

  • Seattle Cancer Care Alliance

    Seattle, Washington, 98109, United States

  • Texas Oncology, Sammons Cancer Center

    Dallas, Texas, 75246, United States

  • The Ohio State University Wexner Medical Center

    Columbus, Ohio, 43210, United States

  • Thomas Jefferson University

    Philadelphia, Pennsylvania, 19107, United States

  • USC Norris Oncology/Hematology-Newport Beach

    Newport Beach, California, 92663, United States

  • USC/Norris Comprehensive Cancer Center

    Los Angeles, California, 90033, United States

  • University Cancer & Blood Center

    Athens, Georgia, 30607, United States

  • University of Arkansas for Medical Sciences

    Little Rock, Arkansas, 72205, United States

  • University of California, Los Angeles

    Los Angeles, California, 90095, United States

  • University of Iowa Hospitals & Clinics

    Iowa City, Iowa, 52242, United States

  • University of Louisville Health Care

    Louisville, Kentucky, 40202, United States

  • University of Pittsburgh Medical Center / Hillman Cancer Center

    Pittsburgh, Pennsylvania, 15232, United States

  • West Virginia University

    Morgantown, West Virginia, 26506, United States