Melanoma combo therapy study halted early
NCT ID NCT04695977
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a new combination treatment for people with advanced melanoma that cannot be removed by surgery or has spread. The combination included an experimental drug injected into tumors (CMP-001) plus an immunotherapy given through a vein (nivolumab). It was compared to nivolumab alone. The study was terminated early after enrolling only 20 participants, so results are limited.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Atlantic Health
Morristown, New Jersey, 07960, United States
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California Cancer Associates for Research & Excellence, Inc.
San Marcos, California, 92069, United States
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Cleveland Clinic
Weston, Florida, 33331, United States
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Duke University Cancer Institute
Durham, North Carolina, 27710, United States
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Hartford Healthcare
Hartford, Connecticut, 06106, United States
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Mayo Clinic Arizona
Phoenix, Arizona, 85054, United States
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Moores Cancer Center at UC San Diego Health
La Jolla, California, 92093, United States
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Seattle Cancer Care Alliance
Seattle, Washington, 98109, United States
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Texas Oncology, Sammons Cancer Center
Dallas, Texas, 75246, United States
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The Ohio State University Wexner Medical Center
Columbus, Ohio, 43210, United States
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Thomas Jefferson University
Philadelphia, Pennsylvania, 19107, United States
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USC Norris Oncology/Hematology-Newport Beach
Newport Beach, California, 92663, United States
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USC/Norris Comprehensive Cancer Center
Los Angeles, California, 90033, United States
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University Cancer & Blood Center
Athens, Georgia, 30607, United States
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University of Arkansas for Medical Sciences
Little Rock, Arkansas, 72205, United States
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University of California, Los Angeles
Los Angeles, California, 90095, United States
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University of Iowa Hospitals & Clinics
Iowa City, Iowa, 52242, United States
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University of Louisville Health Care
Louisville, Kentucky, 40202, United States
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University of Pittsburgh Medical Center / Hillman Cancer Center
Pittsburgh, Pennsylvania, 15232, United States
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West Virginia University
Morgantown, West Virginia, 26506, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can your genes predict your melanoma risk?