Can a prebiotic diet help immunotherapy work better against melanoma?

This study tests whether a diet rich in prebiotic foods can improve the gut microbiome and enhance the effectiveness of first-line immunotherapy in people with advanced melanoma that cannot be removed by surgery. Researchers will enroll 75 adults starting standard immunotherapy and ask them to follow a special prebiotic food-enriched diet. The main goal is to see if the diet increases beneficial gut bacteria and potentially improves treatment response.