Hope for kidney transplant patients with advanced skin cancer: new drug combo aims to fight tumors without losing the donor kidney
NCT ID NCT05896839
First seen Sep 30, 2025 · Last updated Jun 12, 2026 · Updated 41 times
Summary
This study tests a combination of two immunotherapy drugs (nivolumab and ipilimumab) along with two anti-rejection medications (sirolimus and prednisone) in kidney transplant recipients who have advanced skin cancer that cannot be surgically removed or has spread. The goal is to see if this approach can control the cancer while keeping the transplanted kidney healthy. About 16 adults with functioning kidney transplants and certain types of skin cancer will participate.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Emory University Hospital/Winship Cancer Institute
ACTIVE_NOT_RECRUITINGAtlanta, Georgia, 30322, United States
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Huntsman Cancer Institute/University of Utah
RECRUITINGSalt Lake City, Utah, 84112, United States
Contact
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Johns Hopkins University/Sidney Kimmel Cancer Center
RECRUITINGBaltimore, Maryland, 21287, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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Keck Medicine of USC Koreatown
RECRUITINGLos Angeles, California, 90020, United States
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Laura and Isaac Perlmutter Cancer Center at NYU Langone
SUSPENDEDNew York, New York, 10016, United States
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Los Angeles General Medical Center
RECRUITINGLos Angeles, California, 90033, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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Memorial Hospital East
RECRUITINGShiloh, Illinois, 62269, United States
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NYU Langone Hospital - Long Island
SUSPENDEDMineola, New York, 11501, United States
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Northwestern University
RECRUITINGChicago, Illinois, 60611, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Sibley Memorial Hospital
RECRUITINGWashington D.C., District of Columbia, 20016, United States
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Siteman Cancer Center at Christian Hospital
RECRUITINGSt Louis, Missouri, 63136, United States
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Siteman Cancer Center at Saint Peters Hospital
RECRUITINGCity of Saint Peters, Missouri, 63376, United States
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Siteman Cancer Center at West County Hospital
RECRUITINGCreve Coeur, Missouri, 63141, United States
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Siteman Cancer Center-South County
RECRUITINGSt Louis, Missouri, 63129, United States
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UC San Diego Moores Cancer Center
RECRUITINGLa Jolla, California, 92093, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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UM Sylvester Comprehensive Cancer Center at Aventura
RECRUITINGAventura, Florida, 33180, United States
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UM Sylvester Comprehensive Cancer Center at Coral Gables
RECRUITINGCoral Gables, Florida, 33146, United States
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UM Sylvester Comprehensive Cancer Center at Deerfield Beach
RECRUITINGDeerfield Beach, Florida, 33442, United States
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UM Sylvester Comprehensive Cancer Center at Kendall
RECRUITINGMiami, Florida, 33176, United States
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UM Sylvester Comprehensive Cancer Center at Plantation
RECRUITINGPlantation, Florida, 33324, United States
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USC / Norris Comprehensive Cancer Center
RECRUITINGLos Angeles, California, 90033, United States
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University of Kentucky/Markey Cancer Center
RECRUITINGLexington, Kentucky, 40536, United States
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University of Miami Miller School of Medicine-Sylvester Cancer Center
RECRUITINGMiami, Florida, 33136, United States
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University of Miami Sylvester Comprehensive Cancer Center at Sole Mia
RECRUITINGNorth Miami, Florida, 33181, United States
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Contact Email: •••••@•••••
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University of Pittsburgh Cancer Institute (UPCI)
RECRUITINGPittsburgh, Pennsylvania, 15232, United States
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Washington University School of Medicine
RECRUITINGSt Louis, Missouri, 63110, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
Explore the condition pages connected to this study.