New combo therapy targets deadly brain cancer in early trial

NCT ID NCT06829173

First seen Jan 04, 2026 · Last updated Jun 17, 2026 · Updated 23 times

Summary

This early-phase study tests a new drug called XRD-0394 combined with radiation therapy for people with high-grade gliomas, a fast-growing brain cancer. The main goal is to find a safe dose and check for side effects. About 39 adults with newly diagnosed or returning tumors will take part, and some will also get standard chemotherapy depending on their tumor type.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • NYU Langone Health

    RECRUITING

    New York, New York, 10016, United States

Conditions

The condition(s) this trial relates to.

glioma malignant glioma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.