Can a 7-Week brain tumor treatment beat the standard 10-Week plan?
NCT ID NCT02970448
First seen Aug 06, 2026 · Last updated Aug 07, 2026 · Updated 1 time
Summary
This trial asks whether it is safe to shorten the total treatment time for people with newly diagnosed high-grade gliomas, a type of aggressive brain tumor. The usual plan is laser surgery followed by radiation and chemotherapy, taking about 10 weeks. The study tests starting radiation and chemo just 5 days after surgery, aiming to finish in 7 weeks. The goal is to see if this faster approach is safe and might kill cancer cells more effectively.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Laser interstitial thermal therapy (LITT) followed by radiation therapy and chemotherapy
- What this could lead to
- If successful, this could shorten the overall treatment time for brain tumors, potentially making therapy more effective and less burdensome.
- What could go wrong
- This is an early-phase trial with a small number of participants, so results may not apply broadly. There are risks of side effects from the laser surgery and radiation, such as seizures, swelling, or wound issues.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Cleveland Clinic Taussig Cancer institute, Case Comprehensive Cancer Center
Cleveland, Ohio, 44195, United States
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