Genetic hunt for hidden causes of mysterious inflammatory diseases

NCT ID NCT06004349

Recruiting now Knowledge-focused Sponsor: NYU Langone Health Source: ClinicalTrials.gov ↗

First seen Jul 08, 2026 · Last updated Jul 09, 2026 · Updated 1 time

Summary

This study aims to better understand VEXAS syndrome and other autoinflammatory conditions by analyzing participants' DNA from blood, saliva, or skin samples. Researchers hope to discover new genetic variants that cause or contribute to these diseases. The study enrolls people of all ages with known or suspected autoinflammatory disorders, as well as healthy volunteers for comparison.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could uncover new genetic causes of inflammatory diseases, pointing toward better diagnosis or future treatments.
What could go wrong: This is an observational study, not a treatment trial. It may not directly lead to therapies, and genetic discoveries may take years to translate into clinical use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

autoimmune disease autoinflammatory syndrome rheumatic disorder VEXAS syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AUTOIMMUNE DISEASE AUTOINFLAMMATORY DISEASE RHEUMATIC DISEASE VEXAS SYNDOME

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

NYC H+H/Bellevue
RECRUITING

New York, New York, 10016, United States
NYU Langone Health
RECRUITING

New York, New York, 10016, United States

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