Could shorter drug pauses before shoulder surgery reduce flares without raising infection risk?
NCT ID NCT07138898
First seen Jul 09, 2026 · Last updated Jul 10, 2026 · Updated 1 time
Summary
This study looks at whether people with rheumatic diseases (like rheumatoid arthritis or lupus) can safely stop their immunosuppressant medications for a shorter time before elective shoulder replacement surgery. The goal is to see if this approach lowers the chance of disease flares while keeping wound complications and infections at a similar level to longer drug pauses. Researchers will track pain, function, and any need for repeat surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Methotrexate, Sulfasalazine, Hydroxychloroquine, Leflunomide, Azathioprine, Mycophenolate
- What this could lead to
- If successful, this could help doctors fine-tune medication timing before shoulder replacement, potentially reducing disease flares without increasing surgical risks.
- What could go wrong
- This is a small, early-phase study, so results may not apply to all patients. Shorter medication breaks might still lead to flares or infections.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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NYU Langone Health
RECRUITINGNew York, New York, 10016, United States
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