Ear-Zap device could ease nerve woes in kidney patients

NCT ID NCT06927024

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This pilot study tests whether a device that gently stimulates a nerve in the ear (taVNS) is safe and tolerable for people with chronic kidney disease stages 3-5 who have autonomic nervous system dysfunction. Thirty participants will use the device daily for two weeks. The main goals are to see if people can complete the sessions and if serious side effects like abnormal heart rates occur.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

transcutaneous auricular vagus nerve stimulation (taVNS) device

What this could lead to

If it works, this could point toward a drug-free way to improve autonomic nerve function in people with chronic kidney disease.

What could go wrong

This is a very small, early pilot study with only 30 participants, focused mainly on safety and feasibility. It may not show clear benefit, and the device might cause heart rhythm changes or fainting.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chronic kidney disease chronic renal failure syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • NYU Langone Health

    RECRUITING

    New York, New York, 10016, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••