Nyu Langone Health

This study tests whether weekly diabetes education videos sent by text, plus help from a community health worker, can improve blood sugar control in Chinese immigrants with type 2 diabetes. 270 participants will be randomly assigned to get the video program right away or to wait …

This study aims to prevent permanent heart block in unborn babies whose mothers have certain antibodies. Pregnant women at high risk will use a home device to check their baby's heart rate and rhythm. If an early, reversible heart block is detected, mothers will receive quick tre…

This study tests two oral drugs, ladarixin and sotorasib, in people with advanced KRAS G12C mutant non-small cell lung cancer. The goal is to see if the combination is safe and helps control the cancer for longer. About 40 adults with this specific genetic mutation will take part…

This study tests two ways to help Chinese immigrants with type 2 diabetes control their blood sugar: watching educational videos alone, or videos plus support from a community health worker. About 540 adults in New York City will take part. The goal is to see which approach works…

This study tests whether adding financial coaching to standard smoking cessation counseling helps people with low income quit smoking more successfully. About 600 smokers who earn less than 200% of the federal poverty level will be randomly assigned to receive either standard qui…

This study looks at whether giving nutritional supplements to patients who are malnourished before hip or knee replacement surgery can improve their blood markers of nutrition. Researchers will check blood levels of albumin, pre-albumin, and transferrin before and after surgery. …

This study is testing whether a combined face and hand transplant can improve function and appearance for people with severe facial and hand injuries that haven't been helped by standard surgeries or prosthetics. Up to 10 adults aged 18-64 will receive the transplant and be monit…

This study looks at whether checking and improving nutrition before surgery can lower the risk of problems after bowel surgery for inflammatory bowel disease (IBD). About 150 adults having planned bowel surgery will be offered nutritional shakes and guidance. The goal is to see i…

This study tests a program where trained peers deliver blood pressure medication directly to patients' homes and use health technology to support them. The goal is to help 1,140 adults in western Kenya with uncontrolled high blood pressure take their pills regularly and lower the…

This study tests whether combining remote blood pressure monitors with support from community health workers helps Latinx patients better control their hypertension. About 300 adults with uncontrolled high blood pressure will be enrolled. The goal is to see if this approach lower…

This study looks at whether helping clinics change their rules and practices around methadone take-home doses can improve how long people stay in treatment for opioid use disorder. Researchers will work with 36 clinics and about 318 patients to see if offering more take-home dose…

This study tests whether a harm reduction program designed with Black and Latinx communities in mind helps people who use drugs engage more with services and reduce their drug use. About 200 adults who have misused opioids or stimulants in the past month will take part. The goal …

This study compares e-cigarettes to standard nicotine replacement therapy (like patches or gum) plus counseling, to see which helps smokers with opioid use disorder reduce or stop regular cigarettes. About 300 adults in methadone or buprenorphine treatment programs will participa…

This study looks at whether taking probiotics alongside standard treatment can improve immune markers and recovery in people with hip or knee joint infections. About 152 adults aged 18-90 who are scheduled for surgery and antibiotics will be enrolled. Researchers will measure cha…

This study tests whether using portable air cleaners at home can reduce exposure to fine air pollution and help lower blood pressure. About 440 adults with high blood pressure who live in New York City public housing and do not smoke will take part. Participants will use air clea…

This study is for people with HPV-positive throat cancer. It tests whether giving a lower dose of radiation and chemo, based on how well the tumor shrinks halfway through treatment, is safe and effective. About 120 participants will be enrolled. The goal is to see if this approac…

This study looks at whether wearing a continuous glucose monitor (CGM) for two weeks after leaving the hospital helps people with diabetes who are starting insulin for the first time. About 150 adults with type 1 or type 2 diabetes will be randomly assigned to use a CGM or standa…

This study is testing a mobile health toolkit called mWEL to help teachers and parents in Uganda prevent depression and anxiety. About 1,180 participants will use the app as a self-help tool, with optional support from community health workers. The goal is to see if the toolkit i…

This study tests a program called Mom♥Health to help mothers of young children reduce their risk of heart disease. About 40 moms with kids aged 5 or younger will receive support and be guided to health appointments. The goal is to see if this approach is practical and helpful for…

This study looks at whether a light-based treatment called transcranial photobiomodulation (tPBM) can reduce daytime sleepiness in people with obstructive sleep apnea who still feel tired even after using a CPAP machine. About 22 adults with moderate to severe sleep apnea who hav…

This study tests a therapy that briefly restricts blood flow to the leg during low-weight exercises. It aims to help people with Achilles injuries regain strength and reduce pain. About 57 adults aged 18 to 65 who are already in physical therapy will participate. The approach is …

This study tests a one-month program where 46 adults with cannabis use disorder do 20 sessions of home-based brain stimulation (tDCS) while listening to guided mindfulness meditation. Half get real stimulation, half get a sham version. Researchers will check if the treatment is s…

This study tests whether a nutritional supplement taken for three weeks after hip fracture surgery can help older adults (65+) lose less muscle and recover faster. Participants are randomly assigned to receive either the supplement or standard dietary advice. The main goal is to …

This study tests whether adding an extra nerve block (called IPACK) to a standard one (adductor canal block) can better control pain and reduce the need for strong painkillers after knee surgery. About 100 adults having specific knee procedures will be randomly assigned to receiv…

This study tests whether a guided app called SilverCloud, which teaches cognitive behavioral therapy skills, can help high school students with depression or anxiety. About 120 teens who screen positive for symptoms will either use the app or receive standard school-based care. R…

This study tests whether a single dose of psilocybin (the active ingredient in magic mushrooms) can help people with opioid use disorder who continue to use illicit opioids even while on methadone treatment. About 240 participants will receive either a high, medium, or low dose o…

This study looks at whether a modified Atkins diet (low-carb, high-fat) combined with a supervised exercise program can help people with malignant glioma feel better and function better. Fifteen participants will follow the diet and attend two exercise sessions per week for 15 we…

This study tests a 3-week program that uses a Fitbit smartwatch, motivational texts, educational videos, and virtual physical therapy to help older adults (65+) with or without mild dementia become more active. Each participant is paired with a care partner. The goal is to see if…

This study tests a special finger splint called a Relative Motion Orthosis (RMO) to see if it helps people regain finger movement after an injury that caused stiffness. About 64 adults with a stiff middle finger joint will be randomly assigned to get either standard care or stand…

This study tests if a special light therapy (called PBM) can reduce swelling and scarring caused by radiation in head and neck cancer patients. About 60 people who finished radiation at least 3 months ago will be randomly assigned to get real or fake light treatments. The goal is…

This study tests whether adding extra booster sessions and a website to a standard 8-week mindfulness program delivered by phone can better reduce stress, anxiety, and depression in people with heart disease or risk factors like high blood pressure. About 160 participants will be…

This study tests if using a device that sends mild electrical pulses to the calf muscle (neuromuscular electrical stimulation) can help people regain strength and function after ankle fracture surgery. Twenty adults will be randomly assigned to either receive the stimulation plus…

This study tests whether shining near infrared energy (a type of invisible light) on the forehead can change blood flow in the brains of people with major depression. About 120 adults aged 18-65 with depression will receive the light treatment and have their brain activity and de…

This study tests whether freezing certain nerves (cryoablation) during total knee replacement can reduce pain and the need for opioid painkillers afterward. About 215 adults scheduled for knee replacement will be randomly assigned to receive either standard surgery or surgery plu…

This study tests a program called RELAXaHEAD that helps people manage migraines from home using behavioral techniques. About 356 adults with migraines will take part remotely. The goal is to see if the program reduces disability and improves quality of life.

This study tests whether wearing virtual reality (VR) goggles during a colonoscopy or upper endoscopy can lower the amount of sedative medicine needed. Ten adults aged 21 to 65 will receive minimal sedation plus VR to see if it reduces pain, improves satisfaction, and shortens re…

This study looks at how community-centered safety models—like co-response teams, alternative responders, and violence intervention programs—affect violence among youth and young adults in U.S. cities. Researchers will compare data from 15 locations before and after these models s…

This study looks at ways to make it easier for parents of children with multiple chronic health conditions to care for them after leaving the hospital. Researchers will check how well parents understand and follow discharge instructions, and track any health problems that arise w…

This study looks at how well a virtual oncology program works for veterans newly diagnosed with lung, colorectal, prostate, or breast cancer. Researchers will track telehealth visits, quality of care, and costs over 36 months. The goal is to see if this program helps veterans get…

This early-stage study looks at whether giving magnesium sulfate soon after a cardiac arrest is safe and practical for protecting the brain. Researchers will enroll 178 adults who had a cardiac arrest and had their heartbeat restored. The main goal is to see if the treatment can …

This study looks at why people struggle with self-control, especially when trying to avoid tempting snacks. Researchers will ask 300 adults on a diet how much they would pay to avoid junk food, while scanning their brains and testing how stress affects their choices. The goal is …

This study looks at whether a non-invasive light sensor (NIRS) can help predict kidney injury in very premature babies (born before 30 weeks). Researchers will track kidney oxygen levels over the first week of life in 100 infants. The goal is to find early warning signs of kidney…

This study looks at the bacteria living in the lungs of people with a chronic lung condition called bronchiectasis who may also have an infection from NTM bacteria. Researchers will collect sputum and airway samples from 1000 participants to see if certain bacterial patterns are …

This study looks at how difficult childhood experiences might impact the course of multiple sclerosis (MS), especially in Black, Hispanic, and low-income communities. Researchers will use surveys, MRI scans, and blood tests to measure MS severity and quality of life. The goal is …

This study works with the Ramapough Nation to understand how environmental contaminants affect their health. Researchers will test soil, water, and blood samples from 400 tribal members. The goal is to use tradition-centered farming to improve food security and prevent disease.

This study looks at how breathing in dust from the World Trade Center attacks may harm the heart and lungs of FDNY rescue workers. Researchers will measure blood markers and breathing tests in 100 first responders to understand these effects. The goal is to find early signs of di…

This study compares how children and adults with cochlear implants hear sounds versus people with normal hearing. Researchers will test loudness, timing, and pitch perception to find ways to improve implant technology. About 190 participants aged 7 and older will take part. The g…

This study works with the NYC public healthcare system and community partners to help people with limited English get better access to language services. The goal is to make sure everyone can understand their care and receive important preventive health services like screenings a…

This study looks at whether adding a video coaching program (PlayReadVIP) to an existing parenting support program (HealthySteps) helps parents and children more than the support program alone. About 1,000 families with infants up to 6 months old will take part. Researchers will …

This study looks at how mindfulness-based stress reduction (MBSR) affects brain activity in people with generalized anxiety disorder (GAD). About 150 adults with GAD will be randomly assigned to an 8-week MBSR program or a stress education class. Researchers will use brain scans …

This study looks at whether treating depression with a standard antidepressant (escitalopram) can change brain markers linked to Alzheimer's disease. Researchers will compare the drug to a placebo in 60 adults aged 60 and older who have major depression but no memory problems. Th…

This study looks at whether it's practical and acceptable to offer genetic testing for cancer-related genes to women during routine gynecology visits, without needing a specialist referral. About 600 women aged 25-39 will be offered testing, and researchers will track how many ch…

This study tests whether a digital visual tool can help newly diagnosed cancer patients, their caregivers, and doctors better understand treatment options and feel more satisfied with the experience. About 86 adults with breast or head and neck cancer will use the tool and then r…

This study looks at how social media ads affect the food choices and calorie intake of Black and White teenagers aged 13 to 17. Researchers will show participants different ads and measure how many calories they buy or eat, as well as where they look in the ad. The goal is to und…

This study looks at how seeing food in TikTok influencer posts changes what kids ages 10 to 13 buy to eat. About 100 participants will watch either a food-related or non-food TikTok ad, then shop in a pretend online store. The goal is to see if food ads lead to more calorie-heavy…

This study looks at how watching food ads in virtual reality (VR) changes snacking, hunger, and desire to buy food in Black and white young adults aged 18-24. Participants will either see food ads or non-food content in VR for one 2-hour visit. Researchers will measure how much t…

This study tests a mobile app called GeriKit to learn more about older adults (75+) with heart disease. Researchers want to see if the app helps predict health outcomes like hospital readmission or death. The goal is to improve care for this group, not to treat the disease direct…

This study tests whether heart rate measurements from a tDCS headset can predict how well the treatment works for depression. One hundred adults with mild to moderate depression will receive either real or sham brain stimulation at home for 10 days. The goal is to find a simple b…

This study looks at how people with hearing loss in one ear adapt to a cochlear implant. Participants will try four different sound maps during their first month after the implant is turned on. The goal is to see if adjusting the low-frequency settings helps them hear better in n…

This study aims to better understand how the brain creates the feeling of wanting to move. Researchers will use non-invasive brain stimulation and recording techniques in healthy volunteers and people with psychogenic movement disorders or non-epileptic seizures. The goal is to g…

This study looks back at 2,000 patients who had surgery for a type of pancreatic cyst called IPMN. Researchers want to understand why surgery was done and how often these cysts were found to contain cancer. The goal is to improve future decisions about when surgery is truly neede…

This study looks at why some people diagnosed with diabetes in the emergency room don't go to follow-up appointments. Researchers will review medical records, interview patients, and test whether a telehealth visit can help connect them to a regular doctor. The goal is to improve…

This study creates a database to record how well freezing therapy (cryotherapy) works for men with early-stage prostate cancer that hasn't spread. Researchers will track 1,000 participants over time to see how long they live without their PSA levels rising. The goal is to better …

This study enrolls 3,200 adults from immigrant communities in Brooklyn who speak English, Chinese, Spanish, or Bangla. Participants receive subsidized, culturally-tailored fresh produce boxes along with nutrition education, gardening workshops, and help with food benefits. The go…