Nyu Langone Health

This study tests whether a potassium-containing salt substitute is safe and effective for people with end-stage kidney disease on hemodialysis. Twenty participants will try the salt substitute and regular table salt for 16 days each, with a break in between. Researchers will meas…

This early-phase study tests a new type of radiation (lattice radiotherapy) given with chemotherapy and immunotherapy before surgery for oral cavity cancer. About 30 adults with advanced but removable tumors will receive different radiation doses to find the safest level. The goa…

This study tests whether the drug emapalumab can prevent severe side effects (cytokine release syndrome and nerve-related toxicity) in people with lymphoma or multiple myeloma receiving bispecific antibody therapy. About 60 adults will take emapalumab before their cancer treatmen…

This study tests a new type of radiation (lattice radiotherapy) combined with chemotherapy and immunotherapy before standard chemoradiation for people with oropharyngeal cancer. About 60 participants will receive this induction therapy, and their tumor shrinkage will determine if…

This study tests a program called LINKED that uses social networks to encourage people who inject drugs to start HIV prevention medication (PrEP) and medication for opioid use disorder (MOUD). About 398 people in Los Angeles will take part, with half getting the LINKED program an…

This early study tests whether psilocybin (the active ingredient in magic mushrooms) combined with talk therapy can help people with severe irritable bowel syndrome (IBS). Ten adults with hard-to-treat IBS will receive either a high dose of psilocybin or a placebo (niacin) during…

This study compares two types of lasers used to break up kidney stones during a procedure called ureteroscopy. About 70 adults with a single stone or multiple stones totaling 7-20 mm will be randomly assigned to receive either a pulsed Thulium laser or a pulse-modulated Holmium l…

This study compares three different high-intensity walking training programs to see which one best helps people recovering from a stroke improve their balance, walking speed, and endurance. About 20 adults in inpatient rehab will be randomly assigned to one of the programs. The g…

This early-stage study tests whether a single 25 mg dose of psilocybin can help people who still feel emotionally flat or uninterested in things despite taking antidepressants. About 90 adults aged 18-65 will receive either psilocybin or a placebo, and researchers will use brain …

This study tests whether taking tranexamic acid pills for 7 days after total knee replacement helps reduce pain, improve function, and speed recovery. 350 adults scheduled for knee replacement will be randomly assigned to receive either the drug or a placebo. Researchers will tra…

This study looks at whether showing people a live video of their swallowing pressure helps them perform swallowing exercises better. Fifty healthy adults aged 18-40 will swallow with a thin pressure-sensing tube in their nose. Researchers will compare swallowing strength and timi…

This study looks at how overdose prevention centers (OPCs) in New York City impact the risk of fatal and non-fatal overdoses, as well as mental health crises, among adults who use multiple drugs. Researchers will track 500 people who use OPCs or syringe services to see if these c…

This study looks at how vision loss changes the way people move and think during everyday tasks like walking and finding objects. Researchers will test a wearable system called VIS4ION that gives touch and sound cues to help people with low vision navigate more easily. The study …

This study tests a new, non-invasive device called ODIN that measures how well oxygen is being used in the tiny blood vessels of patients with advanced heart failure or cardiogenic shock in the ICU. About 30 adults will have their oxygen measurements taken with the device and com…

This study looks at whether using only a head drape during pediatric tonsillectomy leads to fewer infections within 30 days compared to full-body draping. About 200 children under 18 will be randomly assigned to one of the two draping methods. Researchers will also measure waste …

This study tests a new tool called Communication Compass that gives personalized feedback to medical residents on how they educate and counsel patients. The goal is to improve their communication skills. The study will involve 120 internal medicine residents at NYU Langone Health…

This study looks at whether it is safe to give patients their own salvaged red blood cells back during surgery for pancreatic cancer. About 40 adults will take part, and researchers will track infections and other complications within the first week after surgery. The goal is to …