Nyu Langone Health

This study tests a new type of radiation (lattice radiotherapy) combined with chemotherapy and immunotherapy before standard chemoradiation for people with oropharyngeal cancer. About 60 participants will receive this induction therapy, and their tumor shrinkage will determine if…

This study tests whether taking tranexamic acid (TXA) pills for 7 days after knee replacement surgery helps people recover better. About 350 adults having their first knee replacement will receive either TXA or a placebo. Researchers will track knee function, pain, and movement f…

This study tests a program called LINKED that uses social networks to encourage people who inject drugs to start HIV prevention medication (PrEP) and medication for opioid use disorder (MOUD). About 398 participants will be split into two groups to see if the program works better…

This study tests whether virtual Reiki therapy can help reduce pain and improve quality of life for people with lupus. Twenty adults with lupus will continue their usual care and also receive one weekly virtual Reiki session for 8 weeks. The goal is to see if this gentle, remote …

This study tests an implanted nerve stimulator (Altius®) in 32 leg amputees who still have pain after nerve surgery (TMR or RPNI). Participants will get the device and report changes in pain, prosthesis use, and quality of life over time. The goal is to see if direct nerve stimul…

This study compares two types of lasers used to break up kidney stones during a procedure called ureteroscopy. About 70 adults with kidney stones 7 to 20 mm in size will be randomly assigned to receive either a pulsed Thulium laser or a pulse-modulated Holmium laser. The main goa…

This study tests whether a gel called Barrigel can safely protect the rectum from freezing during a prostate cancer treatment called cryoablation. About 20 men with localized or returning prostate cancer will receive the gel before the freezing procedure. The main goal is to see …

This early-phase study will look at how taking 81 mg of aspirin twice a day affects blood platelets in 30 pregnant women who are at high risk for preeclampsia. Researchers will collect blood samples about four weeks after starting aspirin to measure platelet activity. The goal is…

This study will test a new imaging tool called ATEC IOA during spinal deformity surgery. The goal is to see if it gives more precise measurements than standard X-rays. About 40 adults with spinal deformities will take part. The tool may help surgeons better align the spine during…

This study will test a new feedback system called Communication Compass that gives doctors-in-training personalized reports on how well they educate and counsel patients. About 120 internal medicine residents will take part. The goal is to see if this tool helps improve their com…

This study looks at whether using only a head drape instead of a full-body drape during pediatric tonsillectomy affects infection rates within 30 days after surgery. About 200 children under 18 will be randomly assigned to one of the two draping methods. Researchers will also mea…

This study looks at whether people with chronic hepatitis B who have undetectable virus levels in their blood also have undetectable virus in other body fluids like saliva or semen. Researchers will compare treated patients with suppressed virus to untreated patients with active …

This study tests a new, ultra-fast genetic test (UR-ddPCR) that checks for IDH1-mutant tumor cells during brain surgery. If leftover tumor is found, surgeons can remove more tissue right away. The goal is to see if this approach improves how long patients live without their cance…

This study aims to develop simple office-based walking tests to measure and predict movement problems in young children with neurofibromatosis type 1 (NF1). Researchers will enroll 56 children under 6 years old who can walk independently. Participants will complete walking and de…

This study will look at how using overdose prevention centers (places where people can use drugs under medical supervision) affects the risk of fatal and non-fatal overdoses and mental health crises. Researchers will follow 500 adults in New York City who use these services. The …