Magic mushroom therapy could soothe severe IBS pain

NCT ID NCT06760533

First seen Mar 16, 2026 · Last updated May 01, 2026 · Updated 7 times

Summary

This small early-stage study tests whether psilocybin (the active ingredient in magic mushrooms) combined with talk therapy can help people with severe irritable bowel syndrome (IBS). Ten adults with severe IBS will receive either a high dose of psilocybin or a placebo (niacin) during a guided therapy session. Researchers will measure changes in abdominal pain and overall IBS severity over time to see if this approach is feasible and worth studying further.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • NYU Langone Health

    New York, New York, 10016, United States

Conditions

Explore the condition pages connected to this study.