Magic mushroom compound could restore joy in depressed patients
NCT ID NCT07607938
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-stage study tests whether a single 25 mg dose of psilocybin can help people who still feel emotionally flat or uninterested in things despite taking antidepressants. About 90 adults aged 18-65 will receive either psilocybin or a placebo, and researchers will use brain scans and questionnaires to measure changes in mood and brain activity. The goal is to see if psilocybin can safely improve these lingering symptoms.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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NYU Langone Health
New York, New York, 10016, United States
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