Can popular Weight-Loss drugs quiet the urge to eat for comfort?
NCT ID NCT07803185
First seen Sep 03, 2026 · Last updated Sep 04, 2026 · Updated 1 time
Summary
Researchers are following 60 adults who are starting GLP-1 receptor agonist therapy for weight loss. They will measure changes in anhedonia, the loss of pleasure in activities, and emotional eating behaviors at the start of treatment and again after 6 months. The study uses questionnaires to track these changes, aiming to understand how these drugs might influence mood and eating habits beyond just reducing appetite.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- GLP-1 receptor agonist therapy (a class of weight-loss drugs)
- What this could lead to
- If this study finds links, it could guide how doctors monitor mood and eating habits in people taking GLP-1 drugs for weight loss.
- What could go wrong
- This is an observational study with only 60 participants, so it cannot prove cause and effect. Results may not apply to everyone, and the follow-up is limited to 6 months.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jun 2026
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Adult patients attending the Erciyes University Faculty of Medicine Endocrinology and Metabolism Outpatient Clinic who are newly prescribed GLP-1 receptor agonists for weight management.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 18 years or older * Newly initiated on GLP-1 receptor agonist treatment for weight reduction * Willingness to participate in evaluations at baseline and at the 6-month follow-up * Ability to read and understand Turkish and possess the cognitive capacity to answer questionnaire items * Voluntary provision of written informed consent Exclusion Criteria: * Use of GLP-1 receptor agonists for indications other than weight loss * Cognitive, neurological, or severe psychiatric conditions preventing completion of self-report questionnaires * Substantial missing, inconsistent, or unverifiable questionnaire data compromising analysis integrity * Non-participation or dropout at the 6-month follow-up evaluation
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Erciyes University Medical Faculty Hospitals, Department of Endocrinology and Metabolism
RECRUITINGKayseri, Melikgazi, 38000, Turkey (Türkiye)
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