Scientists track rare brain diseases to uncover early warning signs

NCT ID NCT01799915

Recruiting now Knowledge-focused Sponsor: NYU Langone Health Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study follows 800 adults with synucleinopathies—diseases like Parkinson's, Lewy body dementia, and multiple system atrophy—to learn how they develop and change over time. Researchers will track symptoms, biological markers, and early signs like dizziness on standing or dream-acting to find clues that predict disease spread to the brain. The goal is to better understand these rare conditions, not to test a new treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for DEMENTIA WITH LEWY BODIES are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Lewy body dementia Lewy Body Disease multiple system atrophy Parkinson disease primary orthostatic hypotension pure autonomic failure REM sleep behavior disorder synucleinopathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DEMENTIA WITH LEWY BODIES MULTIPLE SYSTEM ATROPHY NEUROGENIC ORTHOSTATIC HYPOTENSION PARKINSON DISEASE PATIENTS WITH SYNUCLEINOPATHIES PURE AUTONOMIC FAILURE REM SLEEP BEHAVIOR DISORDER SHY-DRAGER DISEASE

Contacts and locations

Locations

Beth Israel Deaconess Medical Center
RECRUITING

Boston, Massachusetts, United States
BioCruces Research Institute - Hospital Universitario de Cruces
RECRUITING

Bilbao, Spain
FLENI - Fundación para la Lucha contras las Enfermedades Neurológicas
RECRUITING

Buenos Aires, Argentina
Mayo Clinic
RECRUITING

Rochester, Minnesota, United States
NYU Medical Center
RECRUITING

New York, New York, 10016, United States
Seoul National University Hospital
RECRUITING

Seoul, South Korea
University of Michigan
RECRUITING

Ann Arbor, Michigan, United States
Vanderbilt Univeristy
RECRUITING

Nashville, Tennessee, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.