Could a brain disease change behavior years before diagnosis?

This study investigates whether people with neurodegenerative diseases—like Alzheimer's, Parkinson's, or ALS—show changes in behavior, social circumstances, or health before and after their diagnosis. Researchers will compare the records of over 61,000 patients with those of matched healthy controls. They will look at criminal records, employment, income, marital status, hospital visits, medication use, and causes of death to identify patterns that might precede or follow the disease.