Frontotemporal dementia
MONDO:0017276Frontotemporal dementia (FTD) comprises a group of neurodegenerative disorders, characterized by progressive changes in behavior, executive dysfunction and language impairment, as a result of degeneration of the medial prefrontal and frontoinsular cortices. Four clinical subtypes have been identified: semantic dementia, progressive non-fluent aphasia, behavioral variant FTD and right temporal lobar atrophy.
Also known as: FTD, MSTD, frontotemporal lobe dementia (FLDEM)
307 clinical trials for this condition and its sub-types.
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Broader categories
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Could a vaccine stop Alzheimer's before it starts? new trial begins
⭐️ VACCINE ⭐️ Recruiting nowThis Phase 1 trial tests an experimental vaccine called AV-1980R that targets tau protein, a key player in Alzheimer's disease. The study enrolls 48 cognitively healthy adults aged 65-80 who have biological signs of early Alzheimer's. Researchers will check if the vaccine is safe…
Phase: PHASE1 • Sponsor: Institute for Molecular Medicine • Aim: ⭐️ VACCINE ⭐️
Last updated Jun 28, 2026 00:00 UTC
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Gut bacteria trial aims to slow ALS and dementia
Disease control Recruiting nowThis study tests whether a special probiotic supplement can change fat-related molecules in the blood of people with ALS and frontotemporal dementia (FTD). Researchers will compare those taking the probiotic to those taking a placebo over 24 weeks. The goal is to see if the probi…
Phase: NA • Sponsor: Centre hospitalier de l'Université de Montréal (CHUM) • Aim: Disease control
Last updated Jul 02, 2026 00:00 UTC
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Could your own stem cells heal your brain? new trial tests it
Disease control Recruiting nowThis study is testing whether stem cells taken from a person's own bone marrow and then given back through the veins and nose can improve brain and nerve function. It includes 500 people with various conditions like stroke, Parkinson's, Alzheimer's, and nerve damage. The goal is …
Phase: NA • Sponsor: MD Stem Cells • Aim: Disease control
Last updated Jun 28, 2026 00:00 UTC
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New hope for rare brain disease: phase 3 trial of NIO752 underway
Disease control Recruiting nowThis study tests an experimental drug called NIO752 in 300 people with progressive supranuclear palsy (PSP), a rare brain disorder that affects movement and balance. Participants are randomly assigned to receive either the drug or a placebo. After the main study, everyone can rec…
Phase: PHASE3 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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New Alzheimer's drug injected into spine shows promise in early safety trial
Disease control Recruiting nowThis early-stage study tests a new drug called LY3954068 in 48 people with mild Alzheimer's symptoms. The drug is given directly into the spinal fluid, either once or twice, to see if it is safe and how it affects Alzheimer's markers. The study lasts up to 100 weeks and includes …
Phase: PHASE1 • Sponsor: Eli Lilly and Company • Aim: Disease control
Last updated Jun 27, 2026 12:09 UTC
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Gene therapy infused directly into brain aims to halt rare dementia
Disease control Recruiting nowThis early-phase trial tests a gene therapy called AVB-101 for people with frontotemporal dementia caused by GRN gene mutations. The therapy delivers a working copy of the GRN gene directly into the brain during a one-time procedure. The study will enroll 18 adults aged 30-75 to …
Phase: PHASE1, PHASE2 • Sponsor: AviadoBio Ltd • Aim: Disease control
Last updated Jun 27, 2026 12:06 UTC
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New study aims to cut unnecessary antibiotics in dementia patients
Disease control Recruiting nowThis study compares a new approach to managing infections in nursing home residents with dementia against usual care. The goal is to see if the new method reduces antibiotic use and avoids stressful procedures like hospital transfers. About 750 residents aged 60 and older with de…
Phase: NA • Sponsor: Hebrew SeniorLife • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC
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Brain zaps to kick the habit: TMS trial targets smokers with mental health struggles
Disease control Recruiting nowThis study tests whether a non-invasive brain stimulation technique called TMS can help people with mental illness quit smoking. Forty daily smokers with psychiatric conditions will receive either TMS or standard care. The goal is to see if TMS is practical and effective in real-…
Phase: PHASE4 • Sponsor: Centre for Addiction and Mental Health • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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Could a pill slow a rare dementia? early trial begins
Disease control Recruiting nowThis early-stage trial tests an oral drug called verdiperstat in 64 people with semantic variant primary progressive aphasia (svPPA), a rare dementia that affects language. The study is double-blind and placebo-controlled, meaning some participants get the drug and some get a pla…
Phase: PHASE1 • Sponsor: Peter Ljubenkov, MD • Aim: Disease control
Last updated Jun 27, 2026 07:54 UTC
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Sleep pill may shield brain from Alzheimer's damage
Disease control Recruiting nowThis study tests whether the insomnia medication lemborexant (Dayvigo) can lower blood markers of brain damage in adults aged 40–65 with insomnia. Twenty participants will take the drug or a placebo for two weeks each, then have their blood tested for proteins linked to Alzheimer…
Phase: PHASE2 • Sponsor: Woolcock Institute of Medical Research • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC
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Eye camera could spot Alzheimer's and Parkinson's early
Diagnosis Recruiting nowThis study is testing a non-invasive eye camera that takes pictures of the retina using different colors of light. Researchers want to see if these images can help detect signs of Alzheimer's, Parkinson's, and other neurodegenerative diseases. About 930 adults over age 30 with or…
Phase: NA • Sponsor: Center for Eye Research Australia • Aim: Diagnosis
Last updated Jun 27, 2026 12:23 UTC
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New PET scan slashes radiation 100-Fold for Alzheimer's detection
Diagnosis Recruiting nowThis study tests a new PET imaging method that uses 10 to 100 times less radiation than current scans to detect Alzheimer's disease and other dementias. Researchers will scan 200 adults (including healthy volunteers) after injecting a radioactive tracer, aiming to see if shorter …
Phase: PHASE2 • Sponsor: Akiva Mintz • Aim: Diagnosis
Last updated Jun 27, 2026 12:07 UTC
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Blood test breakthrough could end painful spinal taps for dementia diagnosis
Diagnosis Recruiting nowThis study is testing whether new blood tests can accurately diagnose the cause of memory loss or dementia, potentially replacing the need for a spinal tap. Researchers will compare blood test results with standard spinal fluid tests in 1,200 people at a memory clinic. If success…
Sponsor: Skane University Hospital • Aim: Diagnosis
Last updated Jun 27, 2026 12:04 UTC
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Simple blood tests could revolutionize dementia diagnosis in your Doctor's office
Diagnosis Recruiting nowThis study aims to make it easier for family doctors to detect early signs of Alzheimer's and other dementias. Researchers will test 1,200 adults with memory or thinking problems using blood tests and brain scans. The goal is to see if these tools can accurately identify who has …
Sponsor: Skane University Hospital • Aim: Diagnosis
Last updated Jun 27, 2026 12:04 UTC
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New study seeks to sharpen Alzheimer's diagnosis with simple tests
Diagnosis Recruiting nowThis study aims to find the best cutoff values for key Alzheimer's-related proteins in spinal fluid and blood to improve diagnostic accuracy. Researchers will compare results from Alzheimer's patients, those with mild memory problems, people with other dementias, and healthy olde…
Sponsor: Capital Medical University • Aim: Diagnosis
Last updated Jun 27, 2026 12:00 UTC
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Simple blood test could revolutionize Alzheimer's diagnosis
Diagnosis Recruiting nowThis study is testing a new blood test called the AD-seeds-detector that looks for specific protein clumps linked to Alzheimer's disease. Researchers will compare the test results from 1,500 people aged 55-75, including those with Alzheimer's, other dementias, and healthy individ…
Sponsor: Capital Medical University • Aim: Diagnosis
Last updated Jun 27, 2026 12:00 UTC
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New video game test could detect hidden social struggles in dementia patients
Diagnosis Recruiting nowThis study is testing a new serious game called REALSoCog to see if it can detect social behavior problems in people with Alzheimer's, Lewy body dementia, or frontotemporal degeneration. Researchers will ask 120 patients to play the game on a laptop, which presents 16 social situ…
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Diagnosis
Last updated Jun 27, 2026 11:01 UTC
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New PET tracers aim to spot tau tangles in rare brain disease
Diagnosis Recruiting nowThis early-phase study tests two new imaging drugs, [18F]ABBV-964i and [18F]ABBV-965i, designed to light up tau protein buildup in the brain during a PET scan. Tau buildup is linked to Progressive Supranuclear Palsy (PSP), a rare movement and thinking disorder. The trial includes…
Phase: EARLY_PHASE1 • Sponsor: Invicro • Aim: Diagnosis
Last updated Jun 27, 2026 08:11 UTC
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New PET tracer aims to light up tau tangles in the brain
Diagnosis Recruiting nowThis early-phase study tests a new radioactive tracer called 18F-JSS20-183A to see if it can safely and accurately detect abnormal tau protein in the brain during PET scans. Researchers will study 90 adults aged 40-85 with tauopathies (like PSP, Alzheimer's, or Parkinson's) and h…
Phase: EARLY_PHASE1 • Sponsor: University of Pennsylvania • Aim: Diagnosis
Last updated Jun 27, 2026 08:06 UTC
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Brain scan showdown: which test best spots Alzheimer's?
Diagnosis Recruiting nowThis study looks at whether a newer type of brain scan (Tau-PET) helps doctors diagnose Alzheimer's disease more accurately than the standard scan (Amyloid-PET). About 120 adults aged 50-85 with mild memory or thinking problems will get both scans. Researchers will track how ofte…
Phase: NA • Sponsor: University Hospital, Geneva • Aim: Diagnosis
Last updated Jun 27, 2026 08:05 UTC
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Your phone could detect dementia: new app listens for clues
Diagnosis Recruiting nowThis study is testing a smartphone app that records and analyzes speech to help diagnose and monitor neurodegenerative conditions like dementia, Parkinson's disease, multiple sclerosis, and motor neuron disease. Researchers will compare speech patterns from 150 people with these …
Sponsor: University of Edinburgh • Aim: Diagnosis
Last updated Jun 26, 2026 18:42 UTC
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Could a sleep pill ward off Alzheimer's? new trial aims to find out
Prevention Recruiting nowThis study tests whether daridorexant, a sleep medication, can help the brain clear proteins linked to Alzheimer's disease. The trial includes 240 adults without dementia, regardless of sleep issues. Participants take the drug or a placebo nightly for one year, and researchers me…
Phase: PHASE2 • Sponsor: Douglas Mental Health University Institute • Aim: Prevention
Last updated Jun 27, 2026 08:05 UTC
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Brain wave sync: a new approach to boost memory in dementia
Symptom relief Recruiting nowThis study tests whether a safe, non-invasive brain stimulation technique called transcranial magnetic stimulation (TMS) can improve working memory in people with dementia. The stimulation is timed to each person's brain waves, measured by EEG, to help brain regions communicate b…
Phase: NA • Sponsor: McMaster University • Aim: Symptom relief
Last updated Jul 01, 2026 00:00 UTC
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3D-Printed fork handles could help dementia patients eat on their own
Symptom relief Recruiting nowThis study tests whether custom 3D-printed cutlery handles can help people with neurodegenerative diseases eat more independently. 75 patients in rehabilitation care will try handles in different sizes, designed to fit their grip. Researchers will measure changes in eating abilit…
Phase: NA • Sponsor: Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
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Bilingual brain boost: new therapy targets language loss in dementia
Symptom relief Recruiting nowThis study tests a speech therapy program for bilingual Spanish-English or Spanish-Catalan speakers with primary progressive aphasia, a condition that slowly damages language abilities. Sixty participants will receive personalized script training via video sessions, while 30 othe…
Phase: NA • Sponsor: Stephanie Grasso • Aim: Symptom relief
Last updated Jun 27, 2026 13:08 UTC
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Zap your brain to sharper thinking? new trial tests TIS for memory loss
Symptom relief Recruiting nowThis study tests a non-invasive brain stimulation technique called temporal interference stimulation (TIS) to see if it can improve cognitive function in people with mild cognitive impairment or early Alzheimer's disease. Sixty participants will receive either real TIS or a sham …
Phase: NA • Sponsor: Tianjin Huanhu Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 13:08 UTC
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New program aims to ease mental health struggles by targeting shared roots
Symptom relief Recruiting nowThis study tests a program called SKILLS that focuses on common factors across different mental health conditions, rather than treating each disorder separately. About 60 adults with stable psychiatric diagnoses will take part. The goal is to see if this approach reduces symptoms…
Phase: NA • Sponsor: University Hospital, Tours • Aim: Symptom relief
Last updated Jun 27, 2026 13:07 UTC
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New program aims to ease stress for dementia caregivers after hospital discharge
Symptom relief Recruiting nowThis study compares two support programs for family and friends caring for Veterans with dementia after a hospital stay. One program, Hospital GamePlan4Care, offers a handbook, online training, and phone coaching tailored to the caregiver. The other provides general education and…
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Jun 27, 2026 13:04 UTC
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Brain games plus walking: a new hope for dementia patients?
Symptom relief Recruiting nowThis study tests whether combining mental exercises (cognitive stimulation therapy) with physical activities (motor stimulation) can improve thinking and mobility in people with mild-to-moderate dementia. About 421 participants aged 65 and older will attend 14 sessions over 7 wee…
Phase: NA • Sponsor: Istituto Superiore di Sanità • Aim: Symptom relief
Last updated Jun 27, 2026 13:03 UTC
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Brain wave beats and 3D music tested to soothe dementia agitation
Symptom relief Recruiting nowThis study tests whether listening to personalized music enhanced with binaural beats (sound patterns that may influence brain waves) or spatialized (3D-like) audio can reduce behavioral and psychological symptoms of dementia, such as agitation and anxiety. Researchers will enrol…
Phase: NA • Sponsor: Maharishi International University • Aim: Symptom relief
Last updated Jun 27, 2026 13:03 UTC
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Can speech therapy help those losing their words? new trial aims to find out
Symptom relief Recruiting nowThis study tests two types of speech therapy for adults with mild-to-moderate primary progressive aphasia, a condition that slowly impairs language. Researchers will compare the therapies in 200 participants to see which better improves communication and reduces caregiver burden.…
Phase: PHASE2 • Sponsor: University of Chicago • Aim: Symptom relief
Last updated Jun 27, 2026 13:00 UTC
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New online program aims to ease burden on dementia caregivers
Symptom relief Recruiting nowThis study tests an online education program called iSupport-Korea, designed for family caregivers of people with dementia. About 160 caregivers will be randomly assigned to use the program or receive usual support, and researchers will track changes in their well-being and confi…
Phase: NA • Sponsor: Chungnam National University • Aim: Symptom relief
Last updated Jun 27, 2026 12:37 UTC
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New online program aims to ease stress for latino Alzheimer's caregivers
Symptom relief Recruiting nowThis study is testing a culturally adapted online education program called Tele-Savvy for Latino caregivers of people with Alzheimer's or related dementias. The program includes weekly video group sessions and short instructional videos over seven weeks. Researchers want to see i…
Phase: NA • Sponsor: University of Rochester • Aim: Symptom relief
Last updated Jun 27, 2026 12:33 UTC
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Can a virtual workout ease caregiver stress? new study tests it
Symptom relief Recruiting nowThis study tests whether a virtual, home-based exercise program can reduce depression and anxiety in family caregivers of people with Alzheimer's disease. Twenty-five caregivers will be randomly assigned to either the exercise program or a wait-list group. The program includes we…
Phase: NA • Sponsor: Indiana University • Aim: Symptom relief
Last updated Jun 27, 2026 12:32 UTC
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Could a mild zap to the brain help you find your words?
Symptom relief Recruiting nowThis Phase II trial tests whether a safe, non-invasive brain stimulation technique called tDCS, combined with language therapy, can improve word-finding in people with primary progressive aphasia (PPA). The study enrolls 180 adults aged 50–90 with certain types of PPA. Participan…
Phase: PHASE2 • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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Shock therapy for dementia agitation? new trial tests ECT
Symptom relief Recruiting nowThis study tests whether adding electroconvulsive therapy (ECT) to usual care can safely reduce severe agitation in people with moderate to severe dementia, including Alzheimer's and other types. Fifty participants will receive ECT sessions with anesthesia, and researchers will m…
Phase: NA • Sponsor: Brent Forester • Aim: Symptom relief
Last updated Jun 27, 2026 12:25 UTC
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Trained volunteers may boost dementia Patients' brain power
Symptom relief Recruiting nowThis study tests whether cognitive stimulation therapy (CST) delivered by trained volunteers can improve thinking and quality of life for people with mild to moderate dementia. 520 participants in Hong Kong will either receive 7 weeks of volunteer-led CST sessions or continue wit…
Phase: NA • Sponsor: The University of Hong Kong • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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New virtual therapy aims to help dementia patients communicate better with loved ones
Symptom relief Recruiting nowThis study tests a personalized, virtual speech therapy program for people with primary progressive aphasia (a type of dementia that affects language) and their communication partners. The goal is to see if the program improves communication and quality of life. About 30 particip…
Phase: NA • Sponsor: Maya Henry • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Can a gentle brain zapping boost memory and mood in early dementia?
Symptom relief Recruiting nowThis study tests whether a non-invasive brain stimulation technique called tDCS, combined with cognitive training, can improve thinking skills and mood in people with mild cognitive impairment or early dementia. Fifty participants will receive both real and placebo stimulation in…
Phase: NA • Sponsor: University of Campania Luigi Vanvitelli • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Could a pill help restore speech in progressive aphasia?
Symptom relief Recruiting nowThis study tests a drug called neflamapimod in 20 people with a language disorder called nonfluent variant primary progressive aphasia (nfvPPA). The goal is to see if the drug is safe and if it can improve language symptoms. Participants will receive either the drug or a placebo …
Phase: PHASE2 • Sponsor: EIP Pharma Inc • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Can zapping the brain slow language decline? new trial investigates
Symptom relief Recruiting nowThis study tests whether two types of non-invasive brain stimulation—TMS and tDCS—can slow language decline in people with primary progressive aphasia, a condition that gradually impairs speech and understanding. Over 6 months, 80 participants will receive either real or sham sti…
Phase: NA • Sponsor: Hospital San Carlos, Madrid • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Could a magnetic helmet spark motivation in dementia?
Symptom relief Recruiting nowThis small pilot study tests whether repetitive transcranial magnetic stimulation (rTMS), a non-invasive brain stimulation technique, can reduce apathy in people with dementia or mild cognitive impairment. Ten participants will receive rTMS, some also taking the medication methyl…
Phase: NA • Sponsor: Sunnybrook Health Sciences Centre • Aim: Symptom relief
Last updated Jun 27, 2026 12:06 UTC
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Could a zappy headband help dementia patients think clearer?
Symptom relief Recruiting nowThis study tests whether a non-invasive brain stimulation technique called tACS can safely improve thinking and memory in people with frontotemporal dementia (FTD). Thirty adults with FTD will receive both real and sham (fake) stimulation in a crossover design, so each person act…
Phase: NA • Sponsor: IRCCS Centro San Giovanni di Dio Fatebenefratelli • Aim: Symptom relief
Last updated Jun 27, 2026 12:02 UTC
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New program aims to ease dementia caregiver burden during nursing home transitions
Symptom relief Recruiting nowThis study tests a program called Connect-Home ADRD that helps nursing home staff and caregivers support dementia patients when they move to home, assisted living, or long-term care. About 360 patients and their caregivers will take part. The goal is to see if the program reduces…
Phase: NA • Sponsor: University of North Carolina, Chapel Hill • Aim: Symptom relief
Last updated Jun 27, 2026 12:01 UTC
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New program aims to help those with early memory loss who live alone
Symptom relief Recruiting nowThis study tests a workshop series designed for people aged 60 and older with early-stage memory loss who live alone. The program provides education and skills training via Zoom to reduce stress, improve well-being, and help with future planning. Researchers will gather feedback …
Phase: NA • Sponsor: Arizona State University • Aim: Symptom relief
Last updated Jun 27, 2026 12:01 UTC
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Could VR therapy help heal emotional wounds?
Symptom relief Recruiting nowThis study is testing whether a virtual reality version of a therapy exercise is practical and helpful for adults (ages 18-65) with psychiatric disorders. Participants will try one VR session and answer questions about their experience. The goal is to see if this approach is acce…
Phase: NA • Sponsor: University Medical Center Groningen • Aim: Symptom relief
Last updated Jun 27, 2026 12:01 UTC
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New online therapy aims to quiet the inner critic
Symptom relief Recruiting nowThis study is testing a type of talk therapy called Emotion Regulation Therapy (ERT) delivered over video for people in New York who struggle with worry, overthinking, or being hard on themselves. The goal is to see if the therapy helps people better manage their emotions and fee…
Phase: NA • Sponsor: Teachers College, Columbia University • Aim: Symptom relief
Last updated Jun 27, 2026 11:03 UTC
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Could a common antidepressant help brain function in frontotemporal dementia?
Symptom relief Recruiting nowThis study tests whether the antidepressant vortioxetine can improve mood symptoms and thinking abilities in people with early-stage behavioral variant frontotemporal dementia (bvFTD). Participants will take the medication for 12 weeks and undergo brain scans and memory tests bef…
Phase: PHASE2 • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated Jun 27, 2026 11:00 UTC
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New app aims to ease the burden on dementia caregivers
Symptom relief Recruiting nowThis study is testing a mobile app called CarePair that helps family caregivers of people with dementia find services and support. About 80 caregivers will use the app for six weeks to see if it is easy to use and helps reduce stress and depression. The goal is to see if the app …
Phase: NA • Sponsor: University of Southern California • Aim: Symptom relief
Last updated Jun 27, 2026 09:11 UTC
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Can online speech therapy help slow language loss in dementia?
Symptom relief Recruiting nowThis study tests personalized speech therapy delivered online for people with primary progressive aphasia (PPA), a condition that slowly destroys language skills. Researchers will enroll 30 adults with mild PPA and tailor exercises to their specific variant. The goal is to see if…
Sponsor: Istituti Clinici Scientifici Maugeri SpA • Aim: Symptom relief
Last updated Jun 27, 2026 09:07 UTC
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New sleep aid studied for those with mental illness
Symptom relief Recruiting nowThis study looks at how well and how safely a new sleep medication, lemborexant, works for people who have both a mental health condition and trouble sleeping. About 121 adults will take the drug for 8 weeks, and researchers will track changes in their sleep quality and any side …
Sponsor: Shanghai Mental Health Center • Aim: Symptom relief
Last updated Jun 27, 2026 09:06 UTC
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Sailing therapy: a new wind for psychiatric care?
Symptom relief Recruiting nowThis study tests whether sailing can help people with psychiatric disorders feel better. Forty adults in France will either take sailing lessons or continue their usual care. Researchers will measure changes in quality of life, mental well-being, and self-esteem to see if sailing…
Phase: NA • Sponsor: Centre hospitalier de Ville-Evrard, France • Aim: Symptom relief
Last updated Jun 27, 2026 08:12 UTC
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Can a home therapy program stop repeat falls in dementia patients?
Symptom relief Recruiting nowThis study tests a program called COTID, where an occupational therapist visits the homes of older adults with dementia who have recently been hospitalized for a fall. The therapist helps make the home safer and trains the caregiver to support the patient. The goal is to see if t…
Phase: NA • Sponsor: University Hospital, Limoges • Aim: Symptom relief
Last updated Jun 27, 2026 08:11 UTC
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Can magnetic pulses ease frontotemporal dementia?
Symptom relief Recruiting nowThis study is testing whether a safe, non-invasive brain stimulation technique called rTMS can help people with frontotemporal dementia (FTLD) or those at risk. 120 participants will receive either real or placebo stimulation for 2 weeks, then all will get real stimulation. Resea…
Phase: NA • Sponsor: Università degli Studi di Brescia • Aim: Symptom relief
Last updated Jun 27, 2026 08:08 UTC
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Can a simple syrup ease care for dementia patients who resist?
Symptom relief Recruiting nowThis study tests if a liquid medicine called midazolam can help elderly patients with moderate to severe memory problems who refuse care. About 30 hospitalized patients will receive the medicine before care to see if it reduces their resistance. The goal is to make necessary care…
Phase: PHASE2 • Sponsor: University Hospital, Grenoble • Aim: Symptom relief
Last updated Jun 27, 2026 08:04 UTC
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Zapping the brain to fight forgetfulness: new dementia trial launches
Symptom relief Recruiting nowThis study tests whether a gentle electrical current applied to the scalp (called transcranial electrical stimulation) can improve memory and thinking in people with dementia. Two hundred participants will receive different types of stimulation (tACS or tRNS) while doing memory g…
Phase: NA • Sponsor: University of Manitoba • Aim: Symptom relief
Last updated Jun 27, 2026 08:00 UTC
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New training helps dementia patients and caregivers tackle chronic pain together
Symptom relief Recruiting nowThis study tests a program that teaches family caregivers how to help their loved ones with mild to moderate dementia manage chronic pain. Researchers will work with 60 people (30 patients and their caregivers) to see if the training improves pain coping and quality of life. The …
Phase: NA • Sponsor: Duke University • Aim: Symptom relief
Last updated Jun 27, 2026 08:00 UTC
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Hearing aid trial aims to calm agitation in Alzheimer's patients
Symptom relief Recruiting nowThis study tests whether a personal sound amplifier, along with hearing training, can reduce troubling symptoms like agitation and distress in older adults with Alzheimer's or related dementias who also have hearing loss. Researchers will enroll 300 people aged 60-100 and their c…
Phase: NA • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated Jun 27, 2026 07:59 UTC
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Brain zaps plus brain games show promise for dementia
Symptom relief Recruiting nowThis study tests whether mild electrical stimulation on the scalp, combined with memory games on an iPad, can improve thinking and memory in people with dementia. About 100 older adults with mild to moderate dementia will receive either real or fake stimulation to see which works…
Phase: NA • Sponsor: University of Manitoba • Aim: Symptom relief
Last updated Jun 27, 2026 07:57 UTC
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New video program aims to ease the burden on FTD family caregivers
Symptom relief Recruiting nowThis study tests a video-based program called STELLA-FTD that helps family members caring for a loved one with frontotemporal dementia (FTD). The program teaches caregivers how to manage difficult behaviors and connect with community resources. Researchers will enroll 640 caregiv…
Phase: NA • Sponsor: Oregon Health and Science University • Aim: Symptom relief
Last updated Jun 27, 2026 07:56 UTC
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New online tool aims to ease burden for dementia caregivers
Symptom relief Recruiting nowThis study tests an 8-week online program called STELLA-R that teaches dementia caregivers a simple ABC method to understand and respond to upsetting behaviors. About 238 caregivers in Oregon, Washington, and Idaho will try the program and report how it affects their stress and r…
Phase: NA • Sponsor: Oregon Health and Science University • Aim: Symptom relief
Last updated Jun 27, 2026 07:55 UTC
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New online course aims to ease the first 100 days of dementia caregiving
Symptom relief Recruiting nowThis study tests an online course for people who have recently become caregivers for a family member or friend with dementia. The program includes weekly video sessions and self-paced materials to help caregivers feel more confident and less stressed. Researchers will measure cha…
Phase: NA • Sponsor: Emory University • Aim: Symptom relief
Last updated Jun 27, 2026 07:54 UTC
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New study tailors dementia care program for African-American families
Symptom relief Recruiting nowThis study is adapting a program called SHARE to better support African-American families dealing with early to moderate dementia. Researchers will work with 120 pairs of people with dementia and their caregivers to test the adapted program. The goal is to see if the program is h…
Phase: NA • Sponsor: Benjamin Rose Institute on Aging • Aim: Symptom relief
Last updated Jun 27, 2026 07:53 UTC
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Can your favourite songs ease dementia symptoms? new study investigates
Symptom relief Recruiting nowThis study explores whether personalised music playlists can help improve behavioural and psychological symptoms in people with dementia. Researchers will work with care home residents and families to create custom playlists and monitor emotional responses. The goal is to develop…
Sponsor: Music for my Mind • Aim: Symptom relief
Last updated Jun 27, 2026 07:52 UTC
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Could a gentle brain zap boost memory in Alzheimer's and lewy body dementia?
Symptom relief Recruiting nowThis study tests whether a gentle, non-invasive brain stimulation technique called tACS can improve memory and thinking in people with Alzheimer's disease, frontotemporal dementia, Lewy body dementia, and related conditions. Two hundred participants will receive either real or sh…
Phase: NA • Sponsor: Kuopio University Hospital • Aim: Symptom relief
Last updated Jun 26, 2026 12:44 UTC
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New brain scans aim to spot inflammation in Alzheimer's and Parkinson's
Knowledge-focused Recruiting nowThis study uses special PET scans to measure inflammation in the brains of people with Alzheimer's, Parkinson's, ALS, and other neurodegenerative diseases. Researchers will compare these scans to those from healthy volunteers to see if inflammation levels differ. The goal is to d…
Phase: PHASE1 • Sponsor: National Institute of Mental Health (NIMH) • Aim: Knowledge-focused
Last updated Jul 03, 2026 23:00 UTC
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New study seeks to uncover links between ALS and dementia
Knowledge-focused Recruiting nowThis study screens 360 adults with neurodegenerative disorders like ALS, frontotemporal dementia, and progressive supranuclear palsy. Researchers will use medical history, physical exams, memory tests, movement analysis, MRI scans, and other tests to find common features and diff…
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS) • Aim: Knowledge-focused
Last updated Jul 02, 2026 00:00 UTC
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Could your Pre-Illness personality shape your brain disease symptoms?
Knowledge-focused Recruiting nowThis study examines whether a person's personality traits before they got sick are linked to the thinking and behavior problems seen in certain brain disorders. Researchers will ask caregivers about the patient's personality from the 10 years before the illness started. The goal …
Sponsor: Nantes University Hospital • Aim: Knowledge-focused
Last updated Jul 01, 2026 00:00 UTC
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Scientists hunt for hidden genes behind movement disorders and dementia
Knowledge-focused Recruiting nowThis study aims to find the genetic causes of movement disorders and dementias by analyzing DNA from up to 12,000 participants, including patients and their family members. Researchers will collect blood or saliva samples and look for gene mutations linked to these conditions. Th…
Sponsor: National Institute on Aging (NIA) • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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Blood tests may reveal earliest signs of Alzheimer's
Knowledge-focused Recruiting nowThis study looks at early changes in mitochondria (the energy centers of cells) and metabolic markers in blood cells of people with Alzheimer's or related dementias. Researchers will compare these measures between those with and without Alzheimer's to find clues about how the dis…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nice • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Can a 48-Hour psychiatrist booking system keep patients out of the ER?
Knowledge-focused Recruiting nowThis study compares two ways to help adults with mental health issues get follow-up care. One group gets usual care after an emergency room visit, while the other uses a new system that books a psychiatrist appointment within 48 hours through their general doctor. Researchers wil…
Phase: NA • Sponsor: Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Massive data dive aims to unlock ALS mysteries
Knowledge-focused Recruiting nowThis study gathers information from the medical records of 1,200 people with ALS and similar conditions. Researchers will use this data to better understand the disease and improve future studies. No experimental treatments are given—the goal is simply to learn from real-world pa…
Sponsor: University of Miami • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Study to uncover hidden mental health struggles in teens at special schools
Knowledge-focused Recruiting nowThis study looks at the mental health of 200 teenagers aged 12 to 16 who attend special educational institutes (ITEPs) in France. Researchers will use psychiatric interviews to find out how many have conditions like depression or anxiety. The goal is to better understand their ne…
Sponsor: University Hospital, Rouen • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:05 UTC
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Can data sharing prevent suicide among Jail-Cycling individuals?
Knowledge-focused Recruiting nowThis study aims to improve suicide prevention for people who move between healthcare and the criminal-legal system. Researchers will link health records, Medicaid data, and jail booking information to identify individuals at risk and coordinate care. Over 1,000 adults with past p…
Phase: NA • Sponsor: Cambridge Health Alliance • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:02 UTC
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Brain scans reveal clues to slowed movement in Alzheimer's
Knowledge-focused Recruiting nowThis study looks at why people with Alzheimer's disease may move more slowly. Researchers will use brain MRI scans and simple reaction time tests in 155 participants with mild cognitive impairment or early dementia. The goal is to link brain lesions to attention-related motor slo…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:39 UTC
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Family genetics study aims to unlock secrets of rare dementia
Knowledge-focused Recruiting nowThis study follows 20 people from families with a genetic risk for frontotemporal dementia (FTD), including those already diagnosed and those at risk. Over five years, researchers will track changes in health and brain function to better understand how the disease develops. The g…
Phase: NA • Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC
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Brain cell study could unlock secrets of dementia
Knowledge-focused Recruiting nowThis study looks at whether special brain cells called tanycytes play a role in Alzheimer's disease and frontotemporal dementia. Researchers will measure hormone levels in blood and spinal fluid from 102 participants to see if these cells help control metabolism and hormone signa…
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC
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Massive gene hunt launched to unlock Alzheimer's secrets
Knowledge-focused Recruiting nowThis study aims to find genes that increase the risk of developing Alzheimer's disease. Researchers are recruiting 10,000 people, including those with Alzheimer's and their family members, from all ethnic backgrounds. By analyzing DNA, they hope to discover new genetic clues that…
Sponsor: Columbia University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:34 UTC
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New quick tests may unlock secrets of brain disease
Knowledge-focused Recruiting nowThis study looks at whether new, quick tests that measure how fast people can move can help doctors diagnose brain diseases like Alzheimer's and predict recovery after a stroke. Researchers will test 129 adults aged 40-85 with stroke or memory problems. The goal is to see if thes…
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC
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Simple memory test could spot dementia early
Knowledge-focused Recruiting nowThis study is testing a new memory test called MAI in 60 adults aged 70 and older. Half have memory disorders like Alzheimer's, and half do not. The goal is to see if the test can tell the difference between the two groups and help doctors detect memory problems earlier.
Phase: NA • Sponsor: Centre Hospitalier de Lens • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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Tiny study aims to unlock secrets of stuttering and aphasia
Knowledge-focused Recruiting nowThis study looks at how the brain plans and produces speech in people who stutter, those with primary progressive aphasia, and healthy speakers. Participants will practice saying made-up words with tricky sound combinations while researchers measure brain activity with MRI and tr…
Phase: NA • Sponsor: Boston University Charles River Campus • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Brain pulse ultrasound may predict dementia progression
Knowledge-focused Recruiting nowThis study is testing a new, non-invasive ultrasound technique called Tissue Pulsatility Imaging (TPI) to measure tiny brain movements. Researchers will compare these measurements in 300 people with mild versus major cognitive disorders. The goal is to see if brain pulse patterns…
Sponsor: University Hospital, Tours • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Brain scans and speech tests could unlock mystery of rare speech disorder
Knowledge-focused Recruiting nowThis study at Mayo Clinic looks at two different types of Progressive Apraxia of Speech, a condition that makes it hard to speak clearly. Researchers will use brain scans, speech assessments, and thinking tests in 47 adults to better tell these types apart. The goal is to improve…
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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Brain study aims to unravel social behavior in Alzheimer's
Knowledge-focused Recruiting nowThis study looks at how social and emotional thinking skills relate to everyday behavior in people with Alzheimer's disease and similar conditions. Researchers will give 120 participants tests of social cognition and ask their study partners to complete behavior checklists. They …
Phase: NA • Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:27 UTC
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AI could revolutionize dementia diagnosis
Knowledge-focused Recruiting nowThis study tests a new AI-powered conversation tool called LUMEN. It helps caregivers describe changes in a loved one's memory and thinking. The goal is to see if the tool is easy to use and can improve the quality of information doctors receive. Sixty caregivers and doctors will…
Sponsor: Northumbria Healthcare NHS Foundation Trust • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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New toolkit aims to improve End-of-Life care talks for dementia patients
Knowledge-focused Recruiting nowThis study tests whether a special training toolkit helps doctors and nurses have better conversations about future medical care with people living with Alzheimer's or related dementias. The researchers will compare clinics that use the toolkit to those that continue usual care, …
Phase: NA • Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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Dementia study probes link between Self-Awareness and reading emotions
Knowledge-focused Recruiting nowThis study looks at how well people with frontotemporal dementia or Alzheimer's disease can recognize emotions in others and how aware they are of their own performance. Researchers will ask 34 participants (ages 50-80) to complete computer tasks and confidence ratings. The goal …
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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Brain scans and tests aim to unlock secrets of cognitive deficits after injury
Knowledge-focused Recruiting nowThis study looks at people with brain damage from strokes, tumors, or other conditions to understand why they have specific thinking problems. Researchers will use brain scans and cognitive tests to link brain areas to deficits. The goal is to learn more about how the brain works…
Phase: NA • Sponsor: University Hospital, Caen • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC
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Massive ALS data bank launches to speed up research
Knowledge-focused Recruiting nowCAPTURE ALS is a long-term study that collects health data and biological samples from 150 people with ALS and related conditions. The goal is to create a shared resource for researchers worldwide to better understand the disease and develop new treatments. No experimental drugs …
Sponsor: University of Alberta • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC
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New web tool aids dementia patients in sharing End-of-Life wishes
Knowledge-focused Recruiting nowThis study is testing a web-based platform called LEAD that helps people in the early stages of Alzheimer's or dementia talk about and document their end-of-life care preferences. The goal is to make it easier for them and their care partners to feel confident in making future me…
Phase: NA • Sponsor: University of Utah • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Massive brain study aims to catch dementia early
Knowledge-focused Recruiting nowThis study follows nearly 3,000 people, including healthy adults and those with memory or movement problems, to learn how brain diseases like Alzheimer's and Parkinson's develop. Researchers use advanced brain scans and tests to track changes over time. The goal is to improve ear…
Phase: NA • Sponsor: Skane University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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Scientists hunt for hidden signs of ALS and FTD in skin and tears
Knowledge-focused Recruiting nowThis study aims to find biological markers (biosignatures) in people with ALS and FTD to make diagnosis more precise. Researchers will analyze samples like spinal fluid, skin, and tears from 230 participants using advanced techniques. The goal is to create a 'disease fingerprint'…
Sponsor: Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:02 UTC
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New coaching tool aims to improve cancer decisions for dementia patients
Knowledge-focused Recruiting nowThis study tests a communication program called COACH-Cog for older adults with both dementia and cancer. It includes a training video for doctors and a coaching session for patients and their care partners. The goal is to see if this helps everyone work together better when maki…
Phase: NA • Sponsor: University of Rochester • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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New study tests nurse support for Ex-Prisoners' health
Knowledge-focused Recruiting nowThis study looks at whether a program with a nurse case manager can help people leaving prison visit a doctor or clinic instead of the emergency room. About 488 adults with a history of substance use and a chronic health condition will take part. Some will get extra support from …
Phase: NA • Sponsor: University of Wisconsin, Madison • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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NIH launches data repository to fuel future research on rare nerve and muscle diseases
Knowledge-focused Recruiting nowThis study gathers medical information from 200 adults with possible nerve, muscle, or autonomic nervous system disorders who are not already in other NIH studies. Participants undergo standard tests like nerve conduction studies, EMG, and physical exams. The data is stored anony…
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS) • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Scientists track how language fades in rare brain disease
Knowledge-focused Recruiting nowThis study follows 500 people with primary progressive aphasia, a condition that slowly damages the brain's language areas. Researchers will use brain scans and language tests to map how the disease progresses over time. The goal is to better understand the disease, not to test a…
Sponsor: Northwestern University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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Major study aims to unlock mysteries of Early-Onset Alzheimer's
Knowledge-focused Recruiting nowThis study follows 850 people aged 40-64 with early-onset cognitive impairment to understand how Alzheimer's disease progresses. Participants undergo cognitive tests, brain scans, and genetic analysis, but no experimental treatment is given. The goal is to gather data that could …
Sponsor: Indiana University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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Could your sleep pattern predict dementia? new study investigates
Knowledge-focused Recruiting nowThis study is following 1,200 people from two memory clinics in Paris to see how sleep patterns, daily routines, and other personal factors relate to different types and stages of dementia. Participants will wear an activity tracker, answer questionnaires, and have cognitive test…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC
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Brain scan could spot early dementia clues
Knowledge-focused Recruiting nowThis study uses a special PET scan to detect tau protein buildup in the brains of healthy older adults and those with mild cognitive impairment. Researchers will compare scan results with memory tests and brain activity patterns to understand how tau affects thinking. The goal is…
Sponsor: Yaakov Stern • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC
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Scientists probe Cholesterol's role in brain decline
Knowledge-focused Recruiting nowThis study looks at how cholesterol and its byproducts relate to different types of dementia, including Alzheimer's and frontotemporal dementia. Researchers will measure these substances in brain tissue, spinal fluid, and blood from 80 adults aged 40-85. The goal is to find patte…
Sponsor: Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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Your eyes could reveal Alzheimer's: new study uses retinal imaging to spot brain disease
Knowledge-focused Recruiting nowThis study uses non-invasive eye scans (OCT and OCTA) to look for changes in the retina that might be linked to brain diseases like Alzheimer's, Parkinson's, and multiple sclerosis. Researchers aim to find early markers that could help diagnose or track these conditions. The stud…
Sponsor: Duke University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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Massive brain disease database aims to unlock secrets of Alzheimer's and ALS
Knowledge-focused Recruiting nowThis study collects information and samples from 1,000 people with or at risk for brain diseases like Alzheimer's, ALS, and frontotemporal degeneration. Researchers will track changes in thinking, language, and brain scans over time. The goal is to build a resource for future stu…
Sponsor: University of Pennsylvania • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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Massive canadian study tracks 1,500 brains to unlock dementia secrets
Knowledge-focused Recruiting nowThis study follows 1,573 adults aged 50 to 90 across Canada, including people with different types of dementia and those with healthy memory. Researchers will use memory tests, brain scans, and blood samples to track how thinking and memory change over time. The goal is to better…
Sponsor: McGill University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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New brain scan study aims to sharpen diagnosis of Parkinson's and dementia
Knowledge-focused Recruiting nowThis study is testing whether new brain imaging techniques can better diagnose diseases like Parkinson's, multiple system atrophy, and frontotemporal dementia. Researchers will use MRI scans and neurological exams in about 94 adults aged 40-85. The goal is to improve how doctors …
Phase: NA • Sponsor: University of Pennsylvania • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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Scientists build a 'Cognitive Atlas' for mental and neurological illnesses
Knowledge-focused Recruiting nowThis study is looking at how people with conditions like schizophrenia, bipolar disorder, depression, and neurological diseases (such as Alzheimer's or stroke) perform on computer-based thinking tests. The goal is to create a detailed map of cognitive strengths and weaknesses acr…
Phase: NA • Sponsor: Centre Hospitalier St Anne • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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New study aims to unlock secrets of memory loss and daily function
Knowledge-focused Recruiting nowThis study looks at how dementia and mild cognitive impairment (MCI) affect thinking, daily activities, and mood. Researchers will assess 151 adults aged 50-86 with these conditions to better understand their challenges. The goal is to improve care by tailoring treatments to each…
Sponsor: IRCCS Centro Neurolesi Bonino Pulejo • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC
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Liquid nerve biopsy could unlock ALS secrets
Knowledge-focused Recruiting nowThis study is collecting nerve samples and biofluids from 400 people with ALS or peripheral neuropathies to find biological markers for early diagnosis and disease tracking. By analyzing individual cells, researchers hope to identify molecular changes that happen before symptoms …
Sponsor: Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:02 UTC
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Thick liquids might help people with swallowing problems take pills safely
Knowledge-focused Recruiting nowThis study looks at whether using a swallow gel or a semi-solid vehicle can help people with neurological conditions swallow pills more easily and safely. Researchers will observe 500 participants, including patients with swallowing disorders and healthy volunteers, as they swall…
Sponsor: Heinrich-Heine University, Duesseldorf • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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Scientists hunt for hidden biomarkers in brain diseases
Knowledge-focused Recruiting nowThis study aims to find new biological markers for neurodegenerative diseases like Alzheimer's, Parkinson's, and ALS. Researchers will analyze genetic, protein, and metabolic data from 1,200 patients to improve diagnosis, predict disease course, and monitor treatment response. Th…
Sponsor: Ospedale Policlinico San Martino • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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Blood test may predict Dementia's path
Knowledge-focused Recruiting nowThis study is looking for 500 people with early dementia or mild cognitive impairment to help develop a way to predict how their disease will progress. Researchers will use blood tests and other models to better understand each person's outlook. The goal is to give patients and d…
Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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New brain scan study aims to unravel mysteries of speech disorder
Knowledge-focused Recruiting nowThis study uses advanced brain scans, including a special PET tracer called AV-1451, to track changes in the brains of 50 people with progressive apraxia of speech (a disorder that affects the ability to coordinate speech movements). Researchers at Mayo Clinic will compare these …
Phase: PHASE4 • Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Brain scan study aims to spot tau protein in rare dementias
Knowledge-focused Recruiting nowThis study uses a special PET scan to measure tau protein buildup in the brains of people with frontotemporal lobar degeneration (FTLD), atypical Alzheimer's disease, and healthy volunteers. Researchers want to see if this scan can help tell these conditions apart. About 72 adult…
Phase: PHASE3 • Sponsor: University of Pennsylvania • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC
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Family DNA bank could unlock Alzheimer's secrets
Knowledge-focused Recruiting nowThis study collects blood or brain tissue from families with two or more members diagnosed with Alzheimer's or dementia. The goal is to build a large DNA bank that researchers can use to find genes linked to the disease. No individual results are returned, but the data may lead t…
Sponsor: Indiana University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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Eye test could spot Alzheimer's early
Knowledge-focused Recruiting nowThis study is testing whether special eye scans can detect changes linked to memory disorders like Alzheimer's and Parkinson's. Researchers will compare eye images from 450 people with and without memory complaints. The goal is to see if these non-invasive scans can help diagnose…
Phase: NA • Sponsor: Fondation Ophtalmologique Adolphe de Rothschild • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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New program aims to ease Veterans' return from prison
Knowledge-focused Recruiting nowThis study is creating a program called START-VET to help veterans with mental illness or substance use disorders who have recently left prison. Researchers will work with 20 veterans to develop transition materials and tools. The goal is to improve quality of life and reduce cri…
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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Spit test could take guesswork out of mental health prescriptions
Knowledge-focused Recruiting nowThis pilot study is testing whether a simple saliva test can help doctors prescribe mental health medications more safely and effectively. 200 adults in Manitoba who are starting or changing psychiatric drugs will provide a DNA sample. The results will be shared with their doctor…
Phase: NA • Sponsor: University of Manitoba • Aim: Knowledge-focused
Last updated Jun 26, 2026 14:55 UTC
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Can training psychiatric staff improve sexual health talks with teens?
Knowledge-focused Recruiting nowThis study looks at whether training psychiatric care teams to talk about sexual health with young patients (ages 15 and up) increases those conversations. Researchers will survey 770 teens hospitalized for psychiatric disorders about their sexual health and any side effects from…
Sponsor: Fondation Santé des Étudiants de France • Aim: Knowledge-focused
Last updated Jun 26, 2026 13:35 UTC