Massive brain disease database aims to unlock secrets of Alzheimer's and ALS

NCT ID NCT04715399

Recruiting now Knowledge-focused Sponsor: University of Pennsylvania Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study collects information and samples from 1,000 people with or at risk for brain diseases like Alzheimer's, ALS, and frontotemporal degeneration. Researchers will track changes in thinking, language, and brain scans over time. The goal is to build a resource for future studies, not to test a new treatment.

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Conditions

The condition(s) this trial relates to.

Alzheimer disease amyotrophic lateral sclerosis Corticobasal Degeneration corticobasal syndrome frontotemporal dementia Lewy body dementia Lewy Body Disease Parkinson disease posterior cortical atrophy primary progressive aphasia progressive supranuclear palsy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALZHEIMER'S DISEASE(AD) AMYOTROPHIC LATERAL SCLEROSIS (ALS) CORTICOBASAL SYNDROME (CBS) FAMILIAL FRONTOTEMPORAL LOBAR DEGENERATION (FFTLD) FRONTOTEMPORAL DEGENERATION (FTD) LEWY BODY DISEASE(LBD) POSTERIOR CORTICAL ATROPHY (PCA) PRIMARY PROGRESSIVE APHASIA(PPA) PROGRESSIVE SUPRANUCLEAR PALSY(PSP)

Contacts and locations

Locations

University of Pennsylvania
RECRUITING

Philadelphia, Pennsylvania, 19104, United States

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