Bilingual brain boost: new therapy targets language loss in dementia

NCT ID NCT05741853

Recruiting now Symptom relief Sponsor: Stephanie Grasso Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a speech therapy program for bilingual Spanish-English or Spanish-Catalan speakers with primary progressive aphasia, a condition that slowly damages language abilities. Sixty participants will receive personalized script training via video sessions, while 30 others will only undergo testing. The goal is to see if therapy improves speech and quality of life, and how bilingualism affects recovery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Video-Implemented Script Training for Aphasia (VISTA) - a behavioral speech therapy
What this could lead to: If successful, this could provide an effective, tailored speech therapy for bilingual individuals with primary progressive aphasia, improving their communication and daily life.
What could go wrong: This is an early-stage trial with only 60 participants, so results may not apply to all bilinguals. The therapy may not work for everyone, and benefits might be modest or temporary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ALZHEIMER DISEASE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Alzheimer disease aphasia apraxia cognitive disorder communication disorder dementia Dysarthria frontotemporal dementia Frontotemporal Lobar Degeneration language disorder neurodegenerative disease primary progressive aphasia semantic dementia speech disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALZHEIMER DISEASE APHASIA APRAXIA, MOTOR BILINGUAL APHASIA COMMUNICATION DISORDERS DEMENTIA DEMENTIA, FRONTOTEMPORAL DYSARTHRIA FRONTOTEMPORAL LOBAR DEGENERATION LANGUAGE DISORDERS NEUROCOGNITIVE DISORDERS NEURODEGENERATIVE DISEASES PRIMARY PROGRESSIVE APHASIA SPEECH DISORDERS

Contacts and locations

Locations

Hospital Clínic de Barcelona
NOT_YET_RECRUITING

Barcelona, 08036, Spain
Hospital de la Santa Creu i Sant Pau
RECRUITING

Barcelona, Barcelona, 08025, Spain
University of Texas at Austin
RECRUITING

Austin, Texas, 78752, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.