APHASIA
Clinical trials for APHASIA explained in plain language.
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New speech therapy trial aims to help stroke survivors find their words
Symptom relief Recruiting nowThis study compares two types of speech therapy for people with aphasia, a language disorder often caused by stroke. One therapy, called Semantic Feature Analysis (SFA), helps people name objects by describing their features. The other adds metacognitive strategy training (SFA+MS…
Matched conditions: APHASIA
Phase: PHASE2 • Sponsor: Teachers College, Columbia University • Aim: Symptom relief
Last updated Jun 27, 2026 14:03 UTC
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Can magnetic pulses help stroke survivors speak again?
Symptom relief Recruiting nowThis study tests whether a non-invasive brain stimulation technique called TMS, combined with language therapy, can improve speech in people who have aphasia after a stroke. Researchers will compare real TMS to a sham (fake) version in 63 participants who had a stroke 2 to 6 week…
Matched conditions: APHASIA
Phase: PHASE2 • Sponsor: University of Pennsylvania • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
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Bilingual brain boost: new therapy targets language loss in dementia
Symptom relief Recruiting nowThis study tests a speech therapy program for bilingual Spanish-English or Spanish-Catalan speakers with primary progressive aphasia, a condition that slowly damages language abilities. Sixty participants will receive personalized script training via video sessions, while 30 othe…
Matched conditions: APHASIA
Phase: NA • Sponsor: Stephanie Grasso • Aim: Symptom relief
Last updated Jun 27, 2026 13:08 UTC
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New support program aims to help spanish-speaking families facing progressive aphasia
Symptom relief Recruiting nowThis study tests an educational support group program for people with progressive aphasia (a language disorder caused by Alzheimer's or other dementias) and their carepartners. The program includes group education, support sessions, and communication skills training. Researchers …
Matched conditions: APHASIA
Phase: EARLY_PHASE1 • Sponsor: University of Texas at Austin • Aim: Symptom relief
Last updated Jun 27, 2026 13:06 UTC
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Magnetic pulses aim to restore speech after stroke
Symptom relief Recruiting nowThis study tests whether a non-invasive brain stimulation technique called rTMS can improve word-finding in people who have trouble speaking after a stroke. Researchers will use MRI scans to guide the stimulation and see how the brain responds. The trial involves 45 participants …
Matched conditions: APHASIA
Phase: NA • Sponsor: University of South Carolina • Aim: Symptom relief
Last updated Jun 27, 2026 13:00 UTC
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Zapping the brain to help stroke survivors find their words again
Symptom relief Recruiting nowThis study tests whether a gentle electrical current applied to the brain can make speech therapy more effective for people with chronic aphasia (trouble speaking or understanding language) after a stroke. About 50 adults who had a stroke at least six months ago will receive eith…
Matched conditions: APHASIA
Phase: NA • Sponsor: University of New Mexico • Aim: Symptom relief
Last updated Jun 27, 2026 12:36 UTC
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App aims to unlock words after stroke
Symptom relief Recruiting nowThis study tests if a digital app called LEXURE can improve language skills in people who have trouble speaking after a stroke (aphasia). About 116 adults who had a stroke at least 3 months ago will either use the app or do workbook exercises. The goal is to see if the app helps …
Matched conditions: APHASIA
Phase: NA • Sponsor: Nunaps Inc • Aim: Symptom relief
Last updated Jun 27, 2026 12:33 UTC
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Your own voice may help you speak again after stroke
Symptom relief Recruiting nowThis study tests a new speech therapy technique for people with aphasia (trouble speaking) after a stroke. Instead of copying a therapist's voice, participants will practice speaking along with an AI-cloned version of their own voice. The goal is to see if this personalized appro…
Matched conditions: APHASIA
Phase: NA • Sponsor: University of South Florida • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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New speech therapy approach aims to help stroke survivors remember words longer
Symptom relief Recruiting nowThis study tests three different naming treatments for people with aphasia, a language disorder often caused by stroke. The goal is to see which approach best helps participants remember words and use them in daily life. Thirty adults with chronic aphasia will practice naming pic…
Matched conditions: APHASIA
Phase: PHASE2 • Sponsor: University of Pittsburgh • Aim: Symptom relief
Last updated Jun 27, 2026 12:06 UTC
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Could a gentle zing to the brain unlock lost words after stroke?
Symptom relief Recruiting nowThis study tests whether a mild electrical current applied to the back of the brain (cerebellar tDCS) can boost language therapy for people who have trouble finding words after a stroke. Sixty adults who had a left-hemisphere stroke at least six months ago and still have aphasia …
Matched conditions: APHASIA
Phase: NA • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated Jun 27, 2026 11:03 UTC
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Sweat it out: High-Intensity workouts may boost language recovery after stroke
Symptom relief Recruiting nowThis study tests whether a 12-week high-intensity exercise program can improve language, thinking, and physical health in 120 adults with aphasia (trouble speaking or understanding language) after a stroke. Participants are randomly assigned to either high-intensity or low-intens…
Matched conditions: APHASIA
Phase: NA • Sponsor: University of California, Berkeley • Aim: Symptom relief
Last updated Jun 27, 2026 11:02 UTC
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Can hand gestures boost word retrieval in aphasia? new study investigates
Symptom relief Recruiting nowThis study tests whether adding hand gestures to standard speech therapy helps Cantonese speakers with aphasia find words more easily. 90 participants will first receive verbal-only therapy, then after a break, switch to therapy that combines gestures with speech. Researchers wil…
Matched conditions: APHASIA
Phase: NA • Sponsor: Hong Kong University • Aim: Symptom relief
Last updated Jun 27, 2026 11:00 UTC
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Can magnetic pulses boost speech therapy for stroke survivors?
Symptom relief Recruiting nowThis study tests whether combining Transcranial Magnetic Stimulation (TMS) with speech therapy can improve language in people with mild aphasia after a stroke. About 24 adults who had a left-brain stroke at least 6 months ago will receive either real or fake TMS along with 10 day…
Matched conditions: APHASIA
Phase: PHASE2 • Sponsor: University of Pennsylvania • Aim: Symptom relief
Last updated Jun 27, 2026 09:10 UTC
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Singing your way back to words: choir therapy tested for stroke survivors
Symptom relief Recruiting nowThis study tests whether joining a community choir for 12 weeks can improve communication and quality of life for people with chronic aphasia (trouble speaking or understanding language) after a stroke. Fifty participants will be randomly assigned to either choir sessions plus ho…
Matched conditions: APHASIA
Phase: NA • Sponsor: University of Ottawa • Aim: Symptom relief
Last updated Jun 27, 2026 09:05 UTC
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App-Based therapy aims to help stroke survivors regain speech
Symptom relief Recruiting nowThis study tests a smartphone app called Zenicom that provides personalized speech therapy exercises for people who have trouble speaking after a stroke (aphasia). Twenty adults with recent stroke and aphasia will either receive standard speech therapy alone or standard therapy p…
Matched conditions: APHASIA
Phase: PHASE2 • Sponsor: Seoul National University Bundang Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 09:04 UTC
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New therapy timing could unlock lasting language recovery for stroke survivors
Symptom relief Recruiting nowThis study tests whether adjusting the timing of speech therapy sessions can help people with aphasia (trouble speaking after a stroke) remember words better and use them in daily life. About 32 adults with chronic aphasia will practice naming pictures using a computer program th…
Matched conditions: APHASIA
Phase: PHASE2 • Sponsor: University of Pittsburgh • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
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Ear device could boost language after stroke – small trial underway
Symptom relief Recruiting nowThis pilot study tests whether a non-invasive device that stimulates the vagus nerve through the ear can help people with chronic aphasia (trouble finding words) after a stroke. Thirty-six participants will use the device at home while doing computer-based speech therapy for six …
Matched conditions: APHASIA
Phase: NA • Sponsor: Sheffield Teaching Hospitals NHS Foundation Trust • Aim: Symptom relief
Last updated Jun 27, 2026 08:02 UTC
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New telemedicine therapy aims to help stroke survivors regain speech
Symptom relief Recruiting nowThis study tests a new behavioral therapy called PICTURE IT, delivered via telemedicine, to help people with aphasia after a stroke. The therapy uses pictures and spoken words to stimulate the right side of the brain, aiming to improve language skills. Researchers will compare it…
Matched conditions: APHASIA
Phase: NA • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC
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Could an antidepressant help stroke survivors regain speech?
Symptom relief Recruiting nowThis study tests whether escitalopram (Lexapro), a common antidepressant, combined with computer-based naming therapy can improve language recovery in people with aphasia after a stroke. About 88 participants who had a left-hemisphere stroke within the past 5 days will receive ei…
Matched conditions: APHASIA
Phase: PHASE2 • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC
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Zapping the brain to unlock lost words after stroke
Symptom relief Recruiting nowThis study tests whether a precise form of brain stimulation (TMS) combined with language therapy can improve word-finding in people who have aphasia after a stroke. Fifty stroke survivors will receive either targeted or control stimulation during therapy sessions. The goal is to…
Matched conditions: APHASIA
Phase: NA • Sponsor: Medical College of Wisconsin • Aim: Symptom relief
Last updated Jun 26, 2026 19:17 UTC
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Brain study aims to improve speech therapy for stroke survivors
Knowledge-focused Recruiting nowThis study looks at how the brain processes auditory feedback during speech in people with aphasia, a communication disorder often caused by stroke. Researchers will test 50 adults with aphasia and 50 healthy adults using speech tasks, EEG, and fMRI. The goal is to find brain mar…
Matched conditions: APHASIA
Phase: NA • Sponsor: The University of Texas at Dallas • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Aphasia ID cards: a simple tool to bridge communication gaps?
Knowledge-focused Recruiting nowThis study tests whether showing an aphasia identification card helps healthy volunteers better understand a person with aphasia. 160 service workers will listen to sentences from a speaker with aphasia, with or without seeing the card first. Researchers will measure comprehensio…
Matched conditions: APHASIA
Phase: NA • Sponsor: University of Massachusetts, Amherst • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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New tool aims to measure Real-Life communication in aphasia patients
Knowledge-focused Recruiting nowThis study aims to develop and test a new scale that measures how well people with aphasia communicate in everyday life, not just in lab tasks. Researchers will enroll 50 Italian-speaking adults with language disorders after a stroke. The goal is to create a tool that considers g…
Matched conditions: APHASIA
Sponsor: IRCCS San Camillo, Venezia, Italy • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Can video therapy help stroke survivors regain speech?
Knowledge-focused Recruiting nowThis study tests whether speech therapy delivered via video call works as well as traditional in-clinic therapy for people with aphasia, a language disorder caused by stroke. One hundred adults who had a stroke at least a year ago will receive either remote or in-person therapy. …
Matched conditions: APHASIA
Phase: NA • Sponsor: University of South Carolina • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:03 UTC
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Mind reading? scientists decode imagined chinese speech from brain activity
Knowledge-focused Recruiting nowThis study investigates whether brain surface recordings can decode Mandarin Chinese speech, including tones, from imagined speech. About 50 participants with brain tumors or epilepsy will have temporary electrodes placed during surgery, and 10 people with severe speech loss will…
Matched conditions: APHASIA
Phase: NA • Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Scientists map brain function in aphasia patients and healthy adults
Knowledge-focused Recruiting nowThis study looks at how memory, learning, and language differ in adults with aphasia (a language disorder from brain injury) compared to healthy adults and seniors. Researchers will test 600 participants using memory and language tasks. The goal is to better understand these cogn…
Matched conditions: APHASIA
Sponsor: Bartosz M. Radtke • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:15 UTC
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Brain & gene clues could unlock aphasia recovery mystery
Knowledge-focused Recruiting nowThis study looks at how genes and brain scans can help predict recovery from aphasia, a language disorder that often follows a stroke. Researchers will enroll 90 adults aged 40-90 who have had a stroke and have trouble speaking or understanding language. By understanding these bi…
Matched conditions: APHASIA
Phase: NA • Sponsor: University of Wisconsin, Madison • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:55 UTC