Can magnetic pulses help stroke survivors speak again?

NCT ID NCT06968663

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether a non-invasive brain stimulation technique called TMS, combined with language therapy, can improve speech in people who have aphasia after a stroke. Researchers will compare real TMS to a sham (fake) version in 63 participants who had a stroke 2 to 6 weeks earlier. Participants will receive 10 sessions of treatment and be followed for 4 months to see if their language skills improve.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Transcranial Magnetic Stimulation (TMS) device and modified Constraint Induced Language Therapy (behavioral therapy)
What this could lead to
If it works, this could point toward a new, non-invasive treatment to help people recover speech after a stroke.
What could go wrong
This is a small, early-phase trial (63 people) testing a device and therapy. It may not show clear benefit, and results may not apply to all stroke survivors.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Pennsylvania

    RECRUITING

    Philadelphia, Pennsylvania, 19014, United States

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