STROKE

This study looks at two ways to help people who have had a stroke lower their blood pressure: checking blood pressure at home, and attending group medical visits to learn about blood pressure management. The researchers want to see if combining both methods works better than home…

This study tests whether adding a cardiac rehabilitation program to standard care helps stroke survivors improve their physical function. Researchers will track 150 adults who had a stroke, measuring walking ability, daily activity, and hospital readmission rates. The goal is to …

This study tests a program that helps people aged 55 and older move from inpatient stroke rehab back to their own homes. Half of the 520 participants will get a stroke education program, while the other half will get a program focused on making home modifications. The goal is to …

This study tests whether placing small filter implants in the neck arteries, on top of standard blood thinners, can lower the risk of another stroke in people with atrial fibrillation who have already had a stroke. About 2,000 participants will be randomly assigned to get the imp…

This study tests whether a spinal cord stimulator, combined with physical therapy, can help improve arm and hand movement in people who have had a stroke. Twenty adults with lasting arm weakness will first do therapy alone, then get a spinal implant and repeat therapy with stimul…

This study compares two common procedures—radiofrequency and cryoablation—for treating persistent atrial fibrillation (AFib), a heart rhythm problem that raises stroke risk. Researchers will track 158 adults over 24 months to see which method better prevents strokes, mini-strokes…

This study tests whether a non-invasive treatment called remote ischemic conditioning (RIC) can help people recover after surgery for a ruptured brain aneurysm. RIC involves briefly inflating a blood pressure cuff on the arm to create short cycles of reduced and restored blood fl…

This study tests whether Diroximel Fumarate, a drug already used for multiple sclerosis, can reduce harmful brain swelling that often occurs after a hemorrhagic stroke (a type of stroke caused by bleeding in the brain). The swelling can worsen recovery, and there is currently no …

This study tests if placing a small tube (stent) in a hardened brain artery during a stroke helps patients recover better than the usual clot-removal methods. It includes 498 adults with severe stroke symptoms whose initial treatment failed due to artery hardening. The goal is to…

This study tests whether starting a special exercise program soon after a stroke can protect the brain from memory loss and dementia. Researchers will enroll 126 people who had a stroke in the past 6 months and measure their thinking skills and brain blood flow over time. The goa…

This early study tests whether a robotic system can help doctors perform procedures on brain blood vessels, such as clearing clots in stroke or blocking blood flow to certain tumors. Ten people already scheduled for these procedures will have them done with robot assistance inste…

This study tests whether two drugs, colchicine and ticagrelor, can reduce inflammation and lower the risk of another stroke, heart attack, or related death in people who have already had a stroke. About 2,800 high-risk participants will take these medications alongside standard c…

This study looks at whether a procedure to remove blood clots from the brain (endovascular thrombectomy) is better than standard medical care for people who have a stroke but already had a moderate-to-severe disability before the stroke. About 1,060 adults with a large-vessel blo…

This study tests whether a simple set of treatments—lowering blood pressure, controlling fever, and managing blood sugar—can help people recover better after a brain bleed (intracerebral hemorrhage). About 3,500 adults in Sweden and Australia will receive either the care bundle o…

This study tests an experimental drug called DM199 in people who have had a moderate stroke and cannot receive standard clot-removal treatments. The goal is to see if DM199 improves recovery and reduces disability. About 728 adults will be randomly assigned to receive either DM19…

This study compares two treatments for arm muscle tightness (spasticity) caused by stroke, spinal cord injury, or brain injury. Thirty adults will receive both surgery and botulinum toxin injections at different times, so each person acts as their own comparison. The goal is to s…

This study tests whether giving a powerful cholesterol-lowering drug (PCSK9 inhibitor) before a clot-removal procedure helps people recover better from a severe stroke. About 652 adults who are having a stroke due to a large blocked artery in the front part of the brain will be r…

This study tests a treatment that combines deep brain stimulation with physical rehab to improve arm function in people who had a stroke 1 to 6 years ago. About 202 participants will receive either the active treatment or a control. The goal is to see if the treatment leads to me…

This study looks at whether adding a blood thinner to standard anti-clotting medicine helps prevent strokes and blood clots in people who develop a new irregular heartbeat after heart bypass surgery. It involves 3,200 adults and compares the benefits against the risk of serious b…

This study tests whether injecting a clot-dissolving medicine directly into the brain's arteries can improve recovery for people having a stroke caused by a medium-sized blood vessel blockage. About 282 adults with this type of stroke will be randomly assigned to receive either t…

This study tests a healthy lifestyle program that has been adapted for Hispanic/Latino people who have had a stroke. The goal is to help participants lose weight and improve health markers like blood sugar and cholesterol. The program includes a smart scale for home use and in-pe…

This study tests whether the drug Dimephosphon can improve recovery in people who have had an ischemic stroke (a stroke caused by a blocked blood vessel in the brain). About 184 adults aged 35-80 will receive either Dimephosphon or a placebo (a dummy treatment) within 24 to 72 ho…

This study tests whether the IV drug clevidipine can lower blood pressure quickly and steadily in people with a bleeding stroke (intracerebral hemorrhage). About 1,000 adults who have had a stroke within the past 12 hours and have high blood pressure will receive either clevidipi…

This study tests whether an artificial intelligence (AI) system can improve arm recovery for people who had a stroke at least 6 months ago. About 192 participants will be split into three groups: one using a rehab game with AI guidance, one using the game without AI, and one rece…

This study tests a new decision-making tool for emergency responders to help get stroke patients in rural areas to the best hospital faster. The goal is to reduce the time from stroke onset to life-saving treatment. About 360 adults with suspected stroke will take part, and resea…

This study is for people who had a stroke with no clear cause and have a small hole in the heart called PFO. Researchers want to see if closing that hole with a special device, along with blood thinners, can lower the chance of having another stroke. About 636 adults will take pa…

This study tests whether hydroxyurea can prevent first strokes in 220 high-risk children with sickle cell anemia in Nigeria. Participants take low or moderate doses of the drug and are monitored for strokes or mini-strokes. The goal is to see if this approach works in real-world …

This study compares two treatments for people having a small type of stroke called a lacunar stroke. One group gets a standard clot-busting medicine through an IV, while the other takes a combination of antiplatelet pills (similar to aspirin). The goal is to see if the pills work…

This early study tests a wireless brain implant from Neuralink that aims to help people with severe paralysis or speech loss communicate by thought. The device is placed in the brain by a robot. Six adults with conditions like ALS, spinal cord injury, or stroke who cannot speak o…

This study tests whether a robotic exoskeleton (Gloreha Sinfonia®) added to standard therapy helps people who recently had a stroke regain better arm and hand control. About 130 adults with mild to moderate arm weakness will be randomly assigned to robot-assisted therapy plus sta…

This study tests whether a program that helps stroke survivors with social needs (like food, housing, or money) can improve their recovery. It includes 275 Black and Hispanic adults aged 18-75 who have had a stroke and face at least three social challenges. The program aims to im…

This study tests whether using a balloon guide catheter that temporarily stops blood flow helps remove clots more effectively in people having a stroke caused by a blocked internal carotid artery. About 364 adults will be randomly assigned to receive either the balloon catheter o…

This study tests whether stroke patients who take blood thinners (FXa inhibitors) can safely receive a standard clot-busting drug (IVT). Current guidelines deny IVT to these patients due to bleeding fears, but new evidence suggests it may be safe. The trial will compare recovery …

This study looks at whether adjusting blood pressure during clot-busting treatment for stroke is safer than the usual approach. About 340 adults with acute ischemic stroke and high blood pressure will take part. The main goal is to see if the adjusted strategy reduces the risk of…

This study tests a device called SSMD to see if it can help people with arm weakness after a stroke or traumatic brain injury. About 150 adults will either use the SSMD device or standard electrical stimulation, along with usual rehab, for 5-6 weeks. The main goal is to measure i…

This study tests a non-invasive wrist monitor that watches for signs of stroke by detecting arm weakness. It aims to catch strokes faster in high-risk hospital patients, especially after heart or blood vessel surgery. The device is designed to give few false alarms and help docto…

This study tests whether a smartphone app that uses virtual and augmented reality can help people who had a stroke improve their arm and hand function at home. Seventy adults who are at least three months past their stroke will either use the app or receive standard therapy for s…

This study tests a program to help low-income people with multiple chronic conditions (like diabetes, heart disease, and lung disease) take their medications correctly after leaving the hospital. The program provides free medications, delivers them to the bedside and then home, a…

This study tests a smartphone app that creates a 'digital twin' of the patient to help manage health after a stroke or related conditions like moyamoya disease or CAA. About 20 adults will use the app daily along with standard care, while another group gets standard care alone. T…

This study tests whether adding the antibiotic minocycline to standard stroke care helps people with moderate strokes recover better. About 1,164 adults will be randomly assigned to receive either minocycline pills for five days plus usual care, or usual care alone. Researchers w…

This study tests whether the clot-busting drug tenecteplase can help people who have had a stroke caused by a blocked artery in the brain, even when treatment starts 24 to 72 hours after symptoms began. About 330 adults with moderate to severe stroke will receive either tenectepl…

This study looks at whether losing weight, with or without exercise, can improve walking and emotional well-being in veterans who have had a stroke and are overweight. About 130 people aged 35-85 who had a stroke at least 6 months ago will take part. Participants will join a life…

This study looks at whether taking blood thinners can prevent strokes in people who have brief episodes of atrial fibrillation (irregular heartbeat) triggered by stress, such as after surgery or a serious illness. About 2,270 participants with additional stroke risk factors will …

This study tests whether combining non-invasive brain stimulation with a special electrical therapy (CCFES) can improve arm and hand movement in people who had a severe stroke at least 6 months ago. 72 participants will receive one of three treatments: brain stimulation on the un…

This study tests whether an over-the-counter supplement called MitoQ and a non-invasive procedure called ischemic conditioning can improve blood vessel function in people who have had a stroke. About 30 stroke survivors will take part. The goal is to see if these treatments can l…

This study compares a new, less invasive surgery to remove blood clots from the brain after a hemorrhagic stroke against standard medical care. About 240 adults with a large brain bleed will be randomly assigned to either the surgery or standard treatment. The goal is to see if t…

This study tests whether taking algae supplements (spirulina or seaweed) for 20 weeks can improve heart health markers and gut bacteria in 150 adults aged 50+ with conditions like heart disease, diabetes, or kidney disease. Participants will be randomly assigned to receive one of…

This study tests a new device called CLAAS that closes a small pouch in the heart to prevent strokes in people with atrial fibrillation (an irregular heartbeat). About 1600 adults at high risk of stroke will be randomly assigned to get either the new device or one of two already-…

This study tests a tool called Savvy that combines phone exercises, a weekly pill organizer, and text reminders to help stroke survivors take their medication as prescribed. The goal is to see if it improves medication adherence and blood pressure control. The study involves 150 …

This early study tests a brain-computer implant that aims to decode imagined speech and allow people with severe paralysis to control computers with their thoughts. Two participants with conditions like ALS, stroke, or spinal cord injury will be enrolled to check the device's saf…

This study is testing whether a telehealth weight loss program can help people who have had a stroke manage their weight and improve their overall health. Researchers will compare the program against a waitlist control group in 94 participants who are at least one year past their…

This study is testing whether keeping blood pressure very low after a successful stroke clot removal surgery leads to better recovery. It will compare a strict blood pressure target to the standard approach in 910 patients who have just had the surgery. Researchers will check if …

This study aims to find the best way to use mental focus instructions to help people recover arm and hand function after a recent stroke. It will compare two different training approaches in 36 participants who are within 6 months of their stroke. The goal is to see if combining …

This study looks at whether using multiple types of CT scans (multimodal CT) can more accurately find the blocked artery in people with medium vessel occlusion stroke. About 622 adults who had a stroke within the last 24 hours will be enrolled. The goal is to see if this approach…

This study tests a portable EEG device called StrokePointer that ambulance crews can use on people with suspected stroke. The goal is to quickly identify patients with a large vessel occlusion stroke who need to go directly to a hospital equipped for clot removal. About 275 adult…

This study aims to develop a quick blood test to tell if a stroke is caused by bleeding or a clot, which is critical for choosing the right treatment. Researchers will test a protein called GFAP, which is known to be high in bleeding strokes, using advanced technology. About 527 …

This study tests whether a special dye called Florbetaben, used with a PET scan, can detect inflamed plaque in the arteries of people who recently had a heart attack or stroke. About 30 participants will receive the dye and undergo imaging to see if it highlights areas of inflamm…

This study looks at 488 people who had a stroke with no clear cause. It compares two methods of a special breathing maneuver (Valsalva) during an ultrasound to find a small hole in the heart called PFO. One method uses standard instructions, the other uses a pressure gauge to gui…

This study checks if a simple, safe eye ultrasound can quickly detect brain swelling and inflammation in ICU patients with meningitis, stroke, or brain tumors. Researchers will measure the optic nerve sheath and compare it with standard tests. If accurate, this low-cost tool coul…

This study is testing a new, sticker-like sensor that listens to a patient's lungs. The goal is to see if it can help doctors screen for pneumonia in high-risk patients, like those recovering from a stroke or on kidney dialysis. About 70 participants will wear the sensor daily fo…

This study tests a music-inspired program called Music4Health to help prevent high blood pressure and stroke in Nigeria. About 1,400 youth (ages 14-24) and their caregivers (ages 40+) will take part. The program uses community-designed music and campaigns to lower blood pressure …

This study tests whether a nurse-led health education program for first-time stroke patients and their family caregivers can reduce the chance of having another stroke. The program focuses on teaching about risk factors and healthy lifestyle changes. Researchers will compare 432 …

This study looks at whether using a 7-day heart monitor can find hidden atrial fibrillation (an irregular heartbeat) in people with higher levels of a heart stress marker (NT-proBNP). About 4,000 adults without known AF will be split into two groups: one gets the monitor, the oth…

This study tests whether escitalopram, a common antidepressant, can make language therapy more effective for people with aphasia (trouble speaking or understanding language) after a stroke. Researchers will enroll 88 adults who had a left-brain stroke within the past 3 months. Pa…

This study tests whether special knee strengthening exercises can improve balance and body awareness (proprioception) in people who had a stroke. About 34 adults, 3 months to 1 year after their stroke, will do these exercises on a machine. The goal is to see if this helps them mo…

This study tests a new rehabilitation program called ACES, which combines acceptance and commitment therapy with strategy training, to help people who have had a stroke rejoin social activities. About 54 chronic stroke survivors living in the community will take part. The program…

This study compares robot-assisted training to standard physical therapy for people who had a stroke 6-24 months ago and still have moderate to severe movement problems. The goal is to see if robot training improves leg function, daily activities, fatigue, and quality of life. Fo…

This study compares three rehabilitation methods—mirror therapy, cognitive orientation to daily occupational performance (CO-OP), and conventional occupational therapy—in 45 adults who had a stroke 3 to 12 months ago. Each group also receives robotic balance training for 4 weeks.…

This study is testing a special suit called Mollii that uses mild electrical pulses to help people with stroke or multiple sclerosis move better and feel better in daily life. About 40 adults who have had a stroke or have MS will wear the suit or a placebo version to see if it im…

This study tests whether adding neuromuscular electrical stimulation (NMES) to standard facial exercises helps people who have facial weakness after a first-time stroke. Researchers will measure changes in facial symmetry using video recordings. The trial aims to recruit 130 adul…

This study tests whether a music-based program done at home can help stroke survivors recover thinking, speech, movement, and mood. One hundred adults who had a stroke at least 3 months ago will either do music exercises 5 times a week for 10 weeks plus usual care, or just usual …

This study tests a new hand therapy that uses a brain-computer interface. 30 people who had a stroke within the last 3 months will either get standard rehab or standard rehab plus this brain-training game. The game uses a headband to measure concentration and moves a virtual hand…

This study looks at whether a gentle electrical stimulation of the vagus nerve (tVNS) combined with a type of hand therapy (mCIMT) can improve arm movement, thinking, and quality of life in people who had a stroke at least 6 months ago. 50 participants will be split into two grou…

This study tests whether using a robotic exoskeleton during walking therapy helps stroke patients regain mobility and independence better than standard rehab. About 50 adults who recently had a stroke and can stand alone will participate. Researchers will measure walking distance…

This study tests a new way to help people with chronic stroke improve their balance. The method uses small, non-invasive vibrations on the skin to give the brain extra sensory information about body position. Researchers will enroll 36 adults who had a stroke at least 6 months ag…

This study looks at whether task-based mirror therapy can ease pain, swelling, and improve arm movement in stroke patients who develop shoulder-hand syndrome. About 34 adults aged 45-75 who had a stroke within the last 6 months will take part. They will do mirror therapy or stand…

This study tests whether practicing on a driving simulator can improve driving skills in veteran stroke survivors. One hundred participants will receive both active training (focusing on speed, lane position, and hazard avoidance) and a control session. The goal is to see if targ…

This study looks at whether listening to music for one hour each day can improve the emotional well-being of people who have had a stroke. About 60 adults aged 50 to 90 who had a stroke at least six months ago will be randomly assigned to listen to music or an audiobook at home f…

This study tests whether adding mild electrical stimulation to arm cycling exercise helps people recovering from a stroke improve their fitness and arm function. About 24 participants with subacute stroke will receive standard rehab plus either arm cycling alone or arm cycling wi…

This study tests a new rehabilitation method for people who have lost part of their vision due to a stroke. The approach combines visual training with gentle electrical stimulation on the brain to try and speed up recovery. Researchers will enroll 24 adults with vision loss from …

This study tests a smart wearable device called gaitQ that uses cues to help people with long-term movement conditions like Parkinson's, stroke, multiple sclerosis, arthritis, and osteoporosis walk better. Researchers will measure improvements in walking speed, step length, and f…

This study tests a new virtual reality therapy that uses motion-tracking and 3D mirrors to help stroke survivors improve arm and hand function. About 56 people who had a stroke 2 to 6 months ago will either get this VR therapy or standard mirror therapy. The goal is to see if the…

This study tests whether a gentle back manipulation (like a chiropractic adjustment) can improve balance and reduce fall risk in people who have had a stroke. About 52 chronic stroke survivors will receive the treatment and be measured on stability and fall risk. The goal is to s…

This study tests whether adding robotic exoskeletons and virtual or augmented reality to treadmill training helps people who have had a stroke improve their walking and daily life. Researchers will compare different training methods in 80 participants to see which works best. The…

This study tests a camera system that uses artificial intelligence to track how well stroke survivors move their arms during robot-assisted therapy. The goal is to see if this feedback helps people avoid bad habits and recover better. About 42 adults who had a stroke 6 months to …

This study tests whether a gentle magnetic brain stimulation (TMS) combined with language therapy can improve word-finding in people who have trouble speaking after a stroke. About 50 adults with left-hemisphere stroke will receive either precise or standard stimulation during th…

This study tests a wrist-worn sensor system (StrokeWear) that reminds and encourages chronic stroke survivors to use their weaker arm during daily activities at home. 32 participants will either use the sensor with a home exercise program or follow standard home exercises alone. …

This study tests a robotic exoskeleton that limits certain arm and trunk movements to help people recovering from a stroke regain better control of their arm. The goal is to see if this approach reduces the use of compensatory movements and improves natural arm function. The tria…

This study tests whether a smartphone app, used alongside standard care, can help people who have had a stroke recover their ability to swallow. The app provides information and tracks progress. Researchers will compare recovery, complications like pneumonia, and quality of life …

This study tests whether using a special visual device that creates the illusion of movement can help people who had a stroke regain better use of their arm and hand. About 66 adults who had a stroke 4 to 10 weeks ago will either get standard therapy or standard therapy plus extr…

This study compares doing rehabilitation exercises at home via video (tele-rehabilitation) versus going to a clinic, to see which better improves thinking and memory after a stroke. About 32 adults aged 50-80 who have had a stroke and have mild to moderate thinking problems will …

This study tests whether gently stimulating the tongue with a device can boost arm recovery in people who had a stroke at least 6 months ago. 74 participants will do arm training with either real or fake tongue stimulation for 4 weeks. Researchers will measure changes in arm func…

This study looks at whether adding music training and group leisure activities to standard hospital rehab helps people recover better after a stroke. About 90 adults who recently had a stroke will be split into three groups: usual rehab alone, usual rehab plus individual music tr…

This study tests whether a home-based telerehabilitation program using the MindMotion GO device can help stroke patients improve motor function. 51 adults who had a stroke more than 30 days ago and have arm or leg weakness will participate. The program provides 300 minutes of wee…

This study tests a hand exercise program for children aged 7 to 12 who had a stroke. The program uses many repetitions and strength-building activities to improve arm and hand movement. Researchers will measure changes in how well children can use their hands in daily tasks. The …

This study compares three types of non-invasive brain stimulation paired with hand therapy to see which best helps stroke survivors open their affected hand. Researchers will enroll 63 adults who had a stroke 6 to 24 months ago. Participants will receive therapy plus one of three…

This study tests whether early brain training (EEG neurofeedback) can improve arm movement after a stroke. About 40 adults who had a stroke within the last 3 weeks will either get real or fake neurofeedback alongside standard rehab. The goal is to see if this extra brain training…

This study tests whether watching functional movements (like walking) combined with rhythmic sounds helps stroke survivors improve their balance and walking ability. Forty adults aged 40-60 who had a stroke 6 months to 2 years ago will be split into two groups: one gets standard …

This study tests whether virtual reality exercises can help people with brain injuries (from stroke, trauma, or tumor) improve their attention and thinking skills. About 135 adults with recent brain injury and attention problems will use gamified VR exercises. The goal is to see …

This study tests whether a non-invasive device that gently stimulates a nerve in the ear can improve arm and hand recovery in people who had a stroke within the last 6 months. About 48 participants will receive either real or placebo stimulation during their regular rehab session…

This study tests a therapy called Constraint-Induced movement therapy for adults who had a stroke at least 6 months ago and have mild weakness in one arm. The therapy involves daily training sessions to improve arm use, along with techniques to encourage using the weaker hand mor…

This study tests whether virtual reality (VR) training that mimics real home settings can improve arm and hand function in people who have had a stroke. About 86 participants will be split into three groups: VR-based task training, standard task training, or traditional occupatio…

This study tests a non-invasive technique called low-intensity focused ultrasound (LIFUS) to see if it can improve arm movement and motor learning in people who have had a stroke. Researchers will try different power levels and timing patterns to find the most effective settings.…

This study tests a smartphone app called ICanWALK that teaches people how to properly fit and use walking aids like crutches, canes, and walkers. About 52 adults who use a walking aid most of the time will either use the app or receive standard care. The goal is to see if the app…

This study tests whether a virtual reality (VR) program can help stroke survivors improve their balance and walking. 38 adults who had a stroke at least 6 months ago will be randomly assigned to either a real VR training with special visual and balance cues, or a sham version wit…

This study tests a home-based telerehabilitation program for stroke survivors who did not receive outpatient therapy. Two hundred participants across Alberta will use wearable sensors and game-like exercises guided remotely by therapists. The goal is to improve arm and hand movem…

This study tests whether a non-invasive device called NESA, which delivers tiny electrical currents, can help stroke survivors with common problems like muscle stiffness, pain, balance issues, and poor sleep. About 30 people who had a stroke 6 months to 6 years ago will receive t…

This small pilot study is testing whether a mild electrical stimulation on the back, combined with balance exercises, can improve stability and reduce fall risk in people who had a stroke over a year ago. Sixteen participants will be randomly assigned to get either real or fake s…

This study tests whether a personalized brain stimulation method (rTMS) can improve arm function in people who had a stroke within the past 3 months. About 120 participants will receive either standard or customized rTMS based on their individual brain reserve. The goal is to see…

This study tests whether a non-invasive brain stimulation technique called high-frequency rTMS can improve cognitive problems that occur after a stroke. Researchers will use brain imaging to see how the treatment affects brain activity. The study involves 40 adults aged 35-75 who…

This study tests if a non-invasive treatment called Extracorporeal Shock Wave Therapy (ESWT) can reduce muscle stiffness (spasticity) in the wrist of chronic stroke patients. Researchers will use ultrasound to objectively measure changes in muscle tightness. The goal is to find a…

This study tests whether adding rhythmic music cues to treadmill walking with thinking tasks improves walking ability and social participation in people who had a stroke at least 6 months ago. About 90 participants will be randomly assigned to one of three training groups. The go…

This study tests whether a personalized exercise program with coaching can help stroke survivors become more physically active. Researchers will compare a group that gets the coaching plus usual care to a group that gets only usual care. The study involves 120 adults who had a st…

This study tests whether a gentle, non-invasive nerve stimulation (applied to the ear or neck) can improve arm movement, thinking skills, and quality of life when paired with standard therapy in people who had a stroke 3–6 months ago. About 54 participants will receive either ear…

This study looks at whether injecting Xeomin® into the arm can improve walking in adults who have had a stroke. Twenty people with arm and leg stiffness will be tested before and 4-6 weeks after the injection using simple walking tests. The goal is to see if treating arm spastici…

This study tests a wearable biofeedback sensor (i-Phagia) that tracks neck muscle activity during swallowing exercises. It aims to see if adding this device to standard therapy improves swallowing in people with chronic stroke or Parkinson's disease. The trial will also compare d…

This study tests whether adding extra arm-hand exercises (called BOOST therapy) to standard care helps people recover better after a stroke. Eighty participants who had a stroke within the last 5 months will be split into two groups: one gets the extra arm-hand training, the othe…

This study tests whether combining a gentle brain stimulation technique (TMS) with speech therapy can improve language in people who have mild aphasia after a stroke. About 24 adults who had a stroke at least 6 months ago will receive 10 sessions of either real or fake TMS along …

This study tests whether adjusting the timing of speech therapy sessions can help people with aphasia (trouble finding words after a stroke) remember words better and use them in daily life. About 32 adults with chronic aphasia will practice naming pictures on a schedule that ada…

This study tests a non-invasive brain stimulation technique called iTBS in 48 adults who had a stroke more than six months ago and still have arm or hand weakness. The goal is to see if adding iTBS to standard rehabilitation can improve motor recovery and understand how the brain…

This study looks at whether playing music during routine hygiene care (like bed baths) can help stroke patients feel more comfortable in the intensive care unit. About 102 adults who recently had a stroke and are in a specialized ICU will take part. After care, patients will rate…

This early study tests whether combining simple passive robots with noninvasive muscle stimulation can help people who have had a stroke regain arm function. Only 4 participants will be enrolled to give feedback on how practical and helpful the device is. The goal is to see if th…

This study tests a new virtual reality therapy designed to help people who have had a stroke regain movement in their affected arm. The therapy uses special VR tasks that require both hands to work together. Researchers will compare this new approach to standard VR mirror therapy…

This study compares two ways to boost mirror therapy for stroke survivors who have leg weakness. One group gets mirror therapy with mild electrical muscle stimulation; the other gets mirror therapy with special sound beats. The goal is to see which combo improves leg movement and…

This study tests a new virtual reality (VR) system that gives real-time feedback to help stroke survivors walk more evenly. 30 people (15 stroke survivors and 15 healthy adults) will try a single session of robot-assisted walking with the VR feedback. The goal is to see if the sy…

This study tests if freezing a nerve in the leg (cryoneurotomy) works as well as surgery to relax a stiff, twisted foot caused by stroke. About 114 adults who had a stroke at least 6 months ago will be randomly assigned to one of the two treatments. The goal is to reduce muscle t…

This study tests whether combining a robot with tai chi movements can help stroke survivors regain arm function better than standard therapy. About 120 adults who had a first stroke within the past year will take part. They will do either robot-assisted tai chi or regular exercis…

This study tests whether mild electrical stimulation to the back of the brain (cerebellum) can boost language therapy for people who have trouble speaking after a stroke. About 60 adults with chronic aphasia will receive either real or fake stimulation during naming practice. The…

This study looks at whether adding mindfulness exercises to standard neuromuscular stimulation can improve lung function, physical abilities, and stress levels in people recovering from a stroke. About 60 adults aged 50-65 will be split into two groups: one gets both treatments, …

This study tests whether adding augmented reality (AR) or virtual reality (VR) to treadmill walking exercises helps stroke survivors improve their balance and walking ability. 66 adults who have had a stroke will be split into three groups: one using VR, one using AR, and a contr…

This study is for adults who had a stroke at least 6 months ago and have trouble using their arm and hand. It tests a therapy that combines movement training with sensory exercises to see if it improves how often and how well they use their affected arm in daily life. Participant…

This study tests whether a mild electrical current applied to the spinal cord can help people who had a stroke regain movement and feeling in their arm and hand. About 20 adults aged 20 to 70 with arm weakness will receive a surgically placed stimulator. Researchers will measure …

This study tests a wearable suit called Neuro20 that uses mild electrical pulses to help muscles work. Researchers want to see if it improves walking distance, muscle strength, and heart rate variability in 30 people who have had a spinal cord injury, stroke, or amputation. Parti…

This study tests a wrist-worn sensor system called StrokeWear to help people who have had a stroke use their weaker arm more in daily life. About 88 participants who had a stroke 1 to 6 months ago will either use the sensor with a home exercise program or follow standard care. Th…

This study compares two types of exercise programs—trunk training and lateral tilt balance training—to see which better improves trunk control, balance, and daily living skills in stroke patients. It involves 44 adults aged 40-75 who had a stroke 6 months to 1.5 years ago and can…

This study tests a small-group, video-based program for people who had a mild or moderate stroke within the last 6 months. The program teaches self-management strategies to improve confidence, daily activity performance, and quality of life. About 100 participants will join from …

This study tests whether a 4-week program combining virtual reality (VR) and real-world walking practice can help stroke survivors walk more confidently in places like shopping malls and streets. Forty adults who had a stroke 9-24 months ago will use VR goggles and game controlle…

This study tests whether adding aerobic exercise (like walking on a treadmill) to standard physical therapy helps stroke survivors recover better. The goal is to improve arm movement, thinking, and mood. The study will enroll 40 Veterans who had a stroke at least 6 months ago and…

This study tests whether a smartphone app powered by artificial intelligence can improve memory and thinking in people who have had a stroke. Forty adults aged 45-60 with lasting cognitive issues will use the app as part of their recovery. The goal is to see if AI-based training …

This study looks at whether doing high-intensity walking training more often helps people who had a stroke at least 6 months ago walk better. Forty adults aged 18-85 who can walk a little on their own will be split into groups with different training schedules. Researchers will m…

This study tests whether a tongue endurance exercise program can improve swallowing in adults who have trouble swallowing after a stroke. About 70 participants will be randomly assigned to do either tongue exercises or a sham therapy at home for 8 weeks. Researchers will measure …

This study tests whether numbing a nerve in the arm or leg can reduce the hard-to-treat pain some people feel after a stroke. Researchers will give 36 adults either a lidocaine, levobupivacaine, or placebo injection twice, two weeks apart, and measure pain changes. The goal is to…

This study tests whether watching swallowing actions—either on video or in real life—can improve swallowing function in stroke patients with dysphagia. 90 participants will be split into three groups, all receiving standard therapy, with two groups also practicing action observat…

This study tests if combining two types of nerve stimulation can improve arm and hand function in people who had a stroke at least 6 months ago. Researchers will enroll 120 adults aged 55-75. Participants receive either the combined stimulation or a placebo, and their motor skill…

This study is testing whether a special vibration system can help older adults and stroke survivors improve muscle strength, balance, and movement, while also reducing pain. Researchers will recruit 80 participants to try the vibration exercises and measure changes in strength, w…

This study tests a personalized form of brain stimulation (tDCS) in 80 adults who had a stroke at least 3 months ago and still have arm weakness. The goal is to see if tailoring the stimulation to each person's brain can improve arm movement and increase brain connectivity. Parti…

This study tests a device implanted in the body that stimulates muscles to improve walking in people who have had a stroke. It involves 6 participants who are at least 6 months post-stroke and have trouble walking. The goal is to see if a customized controller makes walking faste…

This study tests a non-invasive device that stimulates the vagus nerve through the ear (taVNS) combined with occupational therapy to help people who had a stroke more than 6 months ago. The goal is to see if this approach can improve arm and hand movement. 60 adults with arm weak…

This study tests if a non-invasive brain stimulation technique called iTBS can improve balance and leg movement in people who had a stroke more than six months ago. Researchers will compare iTBS combined with physical therapy to therapy alone in 56 adults. The goal is to see if t…

This study tests whether adding gentle vibration to hand exercises helps stroke survivors regain hand function, feeling, and muscle control. 38 participants who had a stroke at least 3 months ago will be randomly assigned to either vibration-enhanced training or standard exercise…

This study tests a 10-week power exercise program for people who had a stroke at least 6 months ago. The goal is to see if fast, burst-style exercises can improve walking, strength, and balance better than standard strength training. Sixty adults will be randomly assigned to eith…

This study compares two ways of using a robot to help people with chronic stroke improve arm and hand function. About 72 participants will receive 18 sessions of robotic therapy over six weeks, focusing either on the shoulder first or the hand first. Researchers will measure move…

This study tests a new, non-invasive brain stimulation technique called mirror-PAS to help stroke patients regain movement and reduce phantom limb pain. 36 adults will try both standard and mirror-based stimulation in separate sessions. The goal is to see which method better prom…

This study tests whether a digital program for insomnia (Sleepio) can improve sleep and motor learning in 100 stroke survivors. Participants use the app or receive usual care, and researchers measure sleep quality and how well they learn movement tasks. The goal is to see if bett…

This study looks at a new way to treat shoulder pain that many people have after a stroke. The pain is thought to be caused by a buildup of a natural substance called hyaluronic acid in the muscles. Researchers will give injections to see if they can reduce pain and improve shoul…

This study tests a robotic glove that reads brain signals to help people who have had a stroke move their affected hand and arm. The goal is to improve function and dexterity. The trial will involve 60 adults who are at least 16 weeks post-stroke and have limited hand movement. P…

This study tests whether a fast form of brain stimulation (accelerated rTMS) can safely improve apathy—loss of motivation and withdrawal—in people who had a stroke at least 6 months ago. About 40 adults aged 40+ will receive either real or fake stimulation to a brain area linked …

This study tests whether vestibular (balance) exercises can reduce fatigue in people who have had a stroke. Thirty adults who had a stroke at least 6 months ago will either do standard rehab or special balance exercises three times a week for one hour. Researchers will measure fa…

This study tests a wearable device called a myoelectric-computer interface (MCI) that helps stroke survivors improve arm movement. The device works by giving feedback on muscle activity to reduce abnormal co-activation that limits coordination. The study will enroll 96 people who…

This early-stage study tests a new exercise device called CUped that helps stroke survivors recover leg movement and improve walking. The device uses robotic technology to prevent bad movement habits and encourages use of the weaker leg. About 12 adults who have had a single stro…

This study tests whether a gentle, non-invasive ultrasound beam aimed at the brain can help people who recently had a stroke regain arm movement. Researchers will enroll 50 adults who had a stroke within the past three months and have some arm weakness. The main goals are to chec…

This study compares two walking therapies for people who have had a stroke: body weight-supported forward and backward walking versus virtual reality-assisted walking. Researchers want to see which approach better improves walking speed, balance, and overall mobility. The study i…

This early-phase study tests a new rehabilitation method called NICE, which uses a computer to show stroke patients how to activate specific muscle groups during arm exercises. The goal is to improve arm function and quality of life. The study involves 48 adults aged 21-80 who ha…

This study tests whether adding visual biofeedback to standard swallowing exercises and electrical stimulation helps stroke survivors with swallowing problems. About 34 adults who had a stroke within the last 6 months will participate. They will do exercises 5 days a week for 4 w…

This study tests whether a gentle nerve stimulation (taVNS) combined with robot-assisted arm training can improve arm movement, breathing strength, and quality of life in people who had a stroke at least six months ago. Thirty adults with moderate to severe arm weakness will rece…

This study tests a program where stroke survivors coach other recent stroke survivors. The goal is to see if this peer support can improve mental well-being, hope, and quality of life. The study involves 20 participants and uses surveys to measure changes over 8 weeks.

This study tests whether doing prism adaptation training together with mild electrical stimulation (TENS) helps stroke survivors who ignore one side of their body more than prism training alone. Twenty participants will be assigned to one of two groups and their attention and arm…

This study looks at two different technology-based therapies—robot-assisted walking training and visual feedback balance training—to see which one helps people who have had a stroke improve their balance and walking. The trial will include 60 adults aged 21-85 who are at least ab…

This study tests a 12-week sitting Tai Chi program for people who have had a stroke and now have trouble with memory or thinking. About 176 participants (88 stroke survivors and 88 caregivers) will be split into two groups: one does Tai Chi three times a week, the other continues…

This study compares two ways of making ankle-foot braces (AFOs) for people with leg weakness from conditions like cerebral palsy, stroke, or spinal cord injury. The traditional method uses a plaster cast, while the newer method uses 3D scanning and printing. Researchers want to s…

This study tests a home-based robotic device combined with mild electrical stimulation to improve leg movement and walking in people who have had a stroke. About 60 adults, at least 6 months post-stroke and able to walk a short distance, will use the robot alone or with stimulati…

This study is testing a mobile app called MAYA that provides cognitive behavioral therapy for anxiety and depression in adults who have had a stroke. The goal is to see if the app is easy to use and acceptable to stroke survivors. Ten participants aged 40-79 will use the app and …

This study tests if adding a vibrating device (Vibramoov®) to robotic walking training helps stroke survivors walk better than robotic training alone. Forty adults who had a stroke at least 3 months ago will take part in a 4-week rehab program. The goal is to see if the vibration…

This study tests whether using a soft robotic hand together with electrical stimulation can help stroke survivors regain hand function better than either therapy alone. About 64 people who had a stroke 3-6 months ago will receive 40-minute sessions three times a week for 8 weeks.…

This study tests whether biofeedback—a tool that gives you real-time visual cues about your swallowing—can improve recovery for people who have trouble swallowing after a stroke. Researchers will compare biofeedback training to standard verbal-only training in 100 stroke survivor…

This study tests whether adding a gentle vibration (kinesthetic feedback) can help stroke survivors who have lost some sense of where their arm is. Thirty people who had a stroke at least six months ago will try reaching for objects and performing everyday tasks like drinking fro…

This study tests two new systems that use virtual reality (VR) or mixed reality (MR) to help people who have had a stroke improve arm and hand function. Participants will use these systems or traditional mirror therapy to see which works best. The goal is to make therapy more eng…

This study tests a new robot that helps people who had a stroke 6 months to 3 years ago improve their walking. The robot has a special mode that encourages patients to actively move their legs, rather than just being moved by the machine. 60 participants will receive 15 training …

This study tests whether adding a home-based telerehabilitation program to usual care helps people with arm weakness after a stroke. About 202 adults who had a stroke 90-150 days ago will be split into two groups: one gets telerehabilitation plus usual care, the other gets usual …

This study tests a web-based rehab program that includes both stroke survivors and their family caregivers. The program focuses on arm exercises and daily activities at home, while also supporting caregivers. Researchers want to see if this approach improves arm function and redu…

This small pilot study tests whether combining two non-invasive therapies—brain stimulation (tDCS) and muscle stimulation (FES)—can improve hand movement in people who had a stroke at least 6 months ago. The goal is to see if these treatments can help the brain and hand work bett…

This study tests whether a hands-on ankle joint technique can improve how stroke survivors sense their ankle position, which is key for balance and walking. Researchers will measure ankle awareness in 26 participants aged 45-75 who are at least two months past their stroke. The g…

This study tests a special thinking strategy for stroke survivors who have trouble paying attention to one side of their body or space, a condition called spatial neglect. The training helps people become more aware of their neglect and learn ways to cope. Researchers want to see…

This study is testing a new robotic ankle exoskeleton to help people who have had a stroke walk more easily. Fifteen stroke survivors will walk on a treadmill, over ground, and on stairs while wearing the device. Researchers will compare walking with the powered exoskeleton to wa…

This study tests whether a high-dose, high-intensity neurorehabilitation program is feasible for stroke patients. About 120 adults with stroke will receive 300 minutes of technology-supported training per week across inpatient, outpatient, and home settings. The goal is to see if…

This study tests a task-specific self-rehabilitation program (TASSRET) for stroke survivors living at home with no access to physiotherapy. Fifty Hausa-speaking adults will use either a video or a manual guide to practice movements. The goal is to see if this approach improves mo…

This study looks at whether moderate or high-intensity walking exercise is better for improving walking in people who had a stroke at least 6 months ago. About 156 participants will be randomly assigned to one of two exercise programs, each done with a physical therapist three ti…

This study tests a new type of speech therapy for people with aphasia, a language disorder often caused by stroke that makes it hard to find words. The therapy uses timed naming exercises that adjust difficulty to balance effort and accuracy, aiming to improve long-term word reca…

This study tests whether a special virtual reality program that stimulates multiple senses can help stroke patients improve their leg movement and thinking skills. Forty adults who have had a stroke and can walk with minor help will be randomly assigned to either the VR therapy o…

This study tests a new speech therapy technique for people with aphasia (trouble speaking) after a stroke. Instead of copying a therapist's voice, participants will practice speaking along with an AI-cloned version of their own voice. The goal is to see if this personalized appro…

This study tests a procedure called cryoneurolysis, which uses cold to freeze specific nerves in the shoulder, to see if it can reduce pain and improve movement in people with spasticity (muscle tightness) after a stroke, brain injury, or other conditions. Half of the 50 particip…

This study is testing a special treadmill that moves each leg at a different speed, combined with virtual reality, to help people who recently had a stroke improve their walking. Researchers want to find out how much training people can safely do in a day. About 72 stroke survivo…

This early study tests whether a device that sends mild electrical pulses to the spinal cord and muscles can improve arm, hand, or leg movement in people with paralysis from spinal cord injury, stroke, or other nerve damage. Up to 64 participants will attend up to 5 sessions per …

This study is testing a device called MyHand 2 that helps stroke survivors with hand weakness. The device is worn on the hand and assists with everyday tasks like gripping and holding. Researchers want to see if the device is easy to use and helpful for recovery. About 60 adults …

This study compares two modern therapies—mirror therapy and virtual reality (VR)—to see which one better improves arm function in people who have weakness on one side after a stroke. About 42 adults, aged 18 to 75, who had a stroke 6 to 12 months ago will be randomly assigned to …

This study tests whether adding intensive virtual reality-based balance and gait training to standard physical therapy helps people who had a stroke within the last six months. About 48 participants will be split into two groups: one gets standard rehab plus VR training, the othe…

This study tests whether adding virtual reality therapy to standard rehabilitation and action observation therapy can improve arm and hand function in people who had a stroke 6 weeks to 6 months ago. About 38 adults will be randomly assigned to two groups: one gets standard care …

This study tests a special exercise program called Task-Oriented Circuit Training (TOCT) to see if it helps stroke survivors improve arm and hand movement. The program involves 15 exercise stations that focus on everyday tasks. Researchers will measure dexterity, grip strength, a…

This study tests a wearable device that delivers gentle, low-frequency electromagnetic fields to the brain to help people who had a stroke more than 6 months ago recover arm function and reduce disability. The trial involves 25 adults aged 18-80 with chronic stroke. Researchers w…

This study tests whether follow-up care by video or phone (telecare) from a stroke nurse can help people recover better after a stroke. About 196 adults who recently had a stroke and own a smartphone will be enrolled. The goal is to see if telecare reduces disability and improves…

This study tests whether combining a gentle brain stimulation technique (tDCS) with training that does two things at once (like walking while counting) can improve walking and thinking in people who had a stroke. Researchers will measure changes in walking speed, mental performan…

This study is testing a new soft robotic glove designed to help people who have had a stroke regain movement in their wrist and forearm. Sixty stroke survivors will be split into three groups to compare the robotic glove with standard rehab. Participants will attend 20 training s…

This study tests whether speech therapy delivered remotely (via video call) works as well as traditional in-clinic therapy for people with aphasia after a stroke. About 100 adults who had a stroke at least a year ago will receive either remote or in-person therapy. The goal is to…

This study tests whether using a virtual reality (VR) treadmill can help people who had a stroke at least 6 months ago improve their walking, balance, and thinking. Thirty participants will either use the VR treadmill or do traditional exercises for 45 minutes, three times a week…

This study tests if a non-invasive magnetic brain stimulation technique called rTMS can reduce fatigue in people who had a stroke more than six months ago. Fatigue is a common and disabling symptom after stroke. Participants will receive rTMS and report their fatigue levels befor…

This study tests whether a gentle, non-invasive brain stimulation technique (tDCS) combined with health education and aerobic exercise can help reduce the severe tiredness many people feel after a stroke. Researchers will enroll 54 adults who had a first stroke within the last 45…

This study is testing a wearable exoskeleton to help improve walking balance in people who have had a stroke. About 21 adults who had a stroke at least 6 months ago and have trouble walking will try the device on a treadmill. Researchers will measure how well the exoskeleton help…

This study looks at whether high-intensity interval training (HIIT) on a stepper machine can improve muscle power in people who had a stroke 1-5 years ago. 66 participants will be split into three groups: HIIT, moderate exercise, or stretching, all training three times a week for…

This study is testing whether a robotic device called Pablo Tyromotion can help improve arm and hand movement in people who have had a stroke. The trial will involve 120 participants aged 45 to 80 who have some basic gripping ability. The goal is to see if this technology can mak…

This study looks at whether low-level laser therapy, a painless light treatment, can reduce muscle tightness and improve walking in people who had a stroke over a year ago. About 22 participants will receive either laser plus standard physical therapy or physical therapy alone fo…

This study is for people who had a stroke at least 6 months ago and now have depression and trouble with focus or planning. Researchers want to see if using an iPad-based brain training program, along with learning new thinking strategies, can improve mood, memory, and daily life…

This study compares robotic gait training to standard physical therapy for people recovering from a stroke. Researchers want to see if using a robotic exoskeleton early in rehab improves walking speed and ability. The study involves 54 adults aged 18-85 who are in inpatient rehab…

This study tests a new approach to help people who lost part of their vision after a stroke. It combines eye movement training with a gentle brain stimulation technique (tDCS) to boost recovery. The trial involves 48 participants who are in the early stages after stroke (less tha…

This study looks at whether fun activities like dance and virtual reality gaming can help people who have had a stroke improve their balance, movement, and daily function. Researchers will compare these alternative therapies to standard rehabilitation in 120 adults aged 18 to 90.…

This study tests whether adding action observation (watching movements) and motor imagery (imagining movements) to standard physical therapy can improve balance, daily function, and quality of life in people who had a stroke within the last year. About 56 participants will be ass…

This study tests a 6-month nurse-led rehabilitation program for stroke patients in Bangladesh after they leave the hospital. The program includes a team of nurses, physical therapists, and occupational therapists to help with self-care and using assistive devices. Researchers wil…

This study compares three add-on therapies—mirror therapy, brain stimulation, and robotic hand training—for stroke survivors who have arm weakness and pain. 120 adults aged 40-80 who had a stroke at least 3 months ago will receive one of these treatments alongside standard rehab.…

This study tests a non-invasive brain stimulation technique called high-definition tDCS to reduce arm stiffness and improve movement in people who have had a stroke. Researchers will enroll 30 adults with arm weakness on one side. The goal is to see if stimulating specific brain …

This study is for people who have had a stroke and want to improve the use of their affected arm and hand. It tests a new approach that combines standard rehabilitation with a technique called mirror priming, which uses visual feedback to help the brain relearn movement. The goal…

This study looks at how different types of walking therapy affect recovery in people who had a stroke 1 to 6 months ago. Researchers want to see if more intense or more specific walking exercises help improve how far people can walk and their quality of life. The study will invol…

This study tests a new way to help people who have had a stroke regain arm movement. It uses a virtual reality system that reads muscle signals to assist arm motions, combined with gentle brain stimulation to boost learning. The goal is to improve arm function and daily life skil…

This study looks at whether high-intensity interval training (short bursts of hard exercise) can help reduce tiredness in people who had a stroke at least 6 months ago. About 60 adults aged 40-80 will be placed into one of three exercise groups for 12 weeks. Researchers will meas…

This study tests whether forced aerobic exercise (using a stationary bike that helps move your legs) can improve arm and leg recovery in people who had a stroke 3-9 months ago. Researchers will measure movement, brain activity, and blood markers of healing, and compare costs to s…

This study tests whether a gentle brain stimulation technique (rTMS) can make walking and thinking training more effective for people who had a stroke at least 6 months ago. About 184 adults aged 50+ will get either real or fake stimulation before each training session, 12 times …

This study tests whether adding musical sound cues to standard walking therapy helps people with Parkinson's disease, stroke, or multiple sclerosis walk better and feel less tired. About 120 adults will either get standard rehab or rehab with these sound cues. The goal is to see …

This study tests whether combining a mild, non-invasive nerve stimulation on the ear (taVNS) with robot-assisted arm training helps stroke survivors improve arm and hand function. Thirty adults who had a stroke at least 6 months ago will receive either real or sham stimulation pl…

This study tests a smartphone app called Zenicom that provides speech therapy exercises for people who have trouble speaking after a stroke. Twenty adults who had a stroke within the last 3 months will either do standard speech therapy alone or add daily app sessions for 2 weeks.…

This study tests whether using a mobile breathing trainer (AiroFit PRO™) for 6 weeks can improve lung function, muscle strength, and quality of life in people with hemiplegia (paralysis on one side) after a stroke. About 54 adults who are at least 3 months post-stroke will be ran…

This study looks at two different types of arm exercises for people who have had a stroke. One group will practice tasks using only their affected arm, while the other group will use both arms together. The goal is to see which method helps improve arm movement and hand skills th…

This study looks at whether a twice-weekly exercise program can improve sleep quality in people who had a stroke at least a year ago and currently have poor sleep. About 62 adults aged 55 and older will take part over 6 months. Researchers will also check if better sleep helps wi…

This study tests whether Vojta therapy, a type of physical therapy that uses gentle pressure on specific body areas to trigger automatic movement, can improve posture and trunk control in people who recently had a stroke. Researchers will enroll 62 adults aged 45-65 who had their…

This study is testing whether a technique called biofeedback can help people who have had a stroke improve the use of their arm and hand. Researchers will measure changes in movement and grip strength in 120 participants aged 45 to 80. The goal is to see if this type of training …

This study tests whether applying kinesio tape to specific neck muscles can help stroke patients swallow more safely. About 25 adults who have trouble swallowing after a stroke will receive the taping and be evaluated using video X-ray. The goal is to see if this simple, non-inva…

This study looks at two different exercise programs—high intensity interval training and intermittent functional training—to see which one better helps stroke survivors improve their heart health, physical abilities, and thinking skills. About 52 adults aged 50-75 who had a strok…

This study is testing whether a smartphone app that shows data from wearable ring and wrist sensors can help people who have had a stroke use their affected arm more during everyday activities. Researchers will enroll 50 chronic stroke survivors to wear the sensors and use the ap…

This study tests whether adding a non-invasive brain stimulation technique called repetitive transcranial magnetic stimulation (rTMS) to standard rehab can improve heart rate control, arm strength, and quality of life in stroke survivors. About 44 adults aged 35-80 who had a stro…

This study compares two ways to help people who had a stroke over 6 months ago become more active. One group follows a personalized exercise program at a special facility, while the other does a self-guided program at home. The goal is to see which approach leads to more daily wa…

This study explores whether hypnosis can help people with stroke, traumatic brain injury, or multiple sclerosis improve their attention and feel less tired. Researchers will use EEG to watch brain activity during hypnosis sessions. The goal is to see if adding hypnosis to standar…

This study tests whether adding pelvic coordination exercises to standard core training improves balance and trunk control in people recovering from a stroke. Researchers will compare two exercise programs in 38 adults aged 45-60 who had a stroke within the last 6 months. The goa…

This study tests whether a home-based e-rehabilitation program (OTHER) helps older adults who have had a stroke improve their ability to perform daily activities, compared to standard occupational therapy. About 171 people aged 60 and older will receive either the OTHER program—w…

This study tests whether combining virtual reality training with a gentle brain stimulation technique (called tDCS) can improve arm and hand function in people who had a stroke at least three months ago. About 100 adults will participate, and researchers will measure changes in m…

This early-stage study at Johns Hopkins University is testing whether psilocybin (the active ingredient in magic mushrooms) is safe for people who had a stroke at least one year ago. Twenty participants will receive the drug alongside therapy to see if it helps their brain become…

This study tests whether personalized exercise plans, created using data from wearable sensors, can help people who had a stroke walk better. Fifty-two adults aged 45-75 who had a stroke at least six months ago will take part. They will do 12 supervised exercise sessions over six…

This study tests whether a non-invasive treatment called extracorporeal shockwave therapy can improve arm and hand function in people who had a stroke six months ago. Researchers will measure movement speed and muscle activity in 50 adults aged 25 to 65. The goal is to find a saf…

This study is testing a new rehabilitation method that combines a brain-computer interface with virtual reality to help people recover arm and hand function after a stroke. Researchers want to see if this high-tech training is better than standard brain-computer training at impro…

This study is testing whether a safe, non-invasive brain stimulation device can help people recover arm and hand movement after a recent stroke. 50 participants with severe arm weakness will receive either real or fake stimulation alongside their normal rehab therapy. The goal is…

This study looks at whether adding visual-motor training (exercises that coordinate what you see with how you move) to standard physiotherapy can improve arm and hand function in people who have had a stroke. Researchers will enroll 38 adults who had a first stroke at least 6 mon…

This study aims to see if fine-tuning the settings of an already-implanted Deep Brain Stimulator (DBS) can better improve movement, speech, and swallowing. It will enroll 60 adults with movement disorders from conditions like stroke or brain injury. Participants will perform task…

This study is testing whether a non-invasive electrical stimulation device placed on the back can help improve walking and balance in people with leg weakness from a stroke. Researchers will test the device alongside walking training in about 115 adults who had a stroke at least …

This study is testing a new digital version of mirror therapy to help people recover arm function after a stroke. It compares the digital therapy to the standard version to see which is more effective and easier for patients to stick with. The goal is to improve movement and help…

This study is testing whether a gentle, non-invasive brain stimulation technique, combined with computer-based brain training games, can help improve memory, focus, and thinking speed in people who have had a minor stroke. Researchers at Johns Hopkins will enroll about 60 stroke …

This study is testing two different speech therapy programs delivered via telemedicine to see which is better at improving conversation skills in people who have trouble speaking after a stroke (aphasia). Researchers will compare a new therapy designed to engage the right side of…

This study is testing whether combining two non-drug treatments—electroacupuncture and a brain stimulation technique called rTMS—helps people recover movement after a stroke better than brain stimulation alone. About 180 adults who had a stroke within the last 6 months will be ra…

This study is testing if a new type of physical therapy using robotic arms and video game-like exercises can help improve both thinking skills and arm movement in adults with Parkinson's disease, multiple sclerosis, or who have had a stroke. Researchers want to see if this high-t…

This study looks at how the brain changes after a stroke and how those changes affect arm and hand movement. Researchers will use brain scans and movement tests to find early signs that predict recovery. The goal is to better understand why some people develop abnormal movement p…

This study looks at why many people feel severe, long-lasting tiredness after a stroke. Researchers will measure heart rate, blood pressure, and heart function in 250 stroke patients to see if problems with the body's automatic control system are linked to fatigue. The goal is to…

This study is observing about 10,000 adults who have had a stroke and received the clot-busting drug tenecteplase as part of their normal care. Researchers will track their recovery and any side effects for 90 days to see how well the drug works in real-world settings across many…

This study is following 5,000 adults in Hong Kong who either have a brain disease (like stroke or dementia) or are at high risk. Researchers will collect medical records and survey data over time to identify what factors lead to brain diseases. The goal is to find ways to keep br…

This study explores whether a brain-computer interface (BCI) can help people with motor disorders control assistive devices just by thinking about moving. Researchers will test 100 healthy volunteers and people with conditions like spinal cord injury or stroke. The goal is to imp…

This study is testing a new plate imaging system to see if it can accurately measure how much food stroke patients eat while in the hospital. About 50 patients on a stroke rehabilitation ward will have their meals photographed and analyzed for calories and nutrients. The goal is …

This study follows 213 adults recovering from a first ischemic stroke to see if the number of daily rehabilitation sessions affects their recovery at six months. Researchers will compare people whose stroke was caused by atrial fibrillation with those who had other causes. The go…

This study looks at why people who have had a stroke often have trouble coordinating their legs when walking. Researchers will measure brain and nerve signals in 50 chronic stroke survivors to find the root causes. The goal is to gather knowledge that could lead to better walking…

This study aims to develop a non-invasive way to measure pressure inside the skull (intracranial pressure) using a device placed on the head, avoiding the need for surgery. Researchers will collect data from 581 patients who already require invasive monitoring as part of their ca…

This study looks at swelling that happens around a brain bleed (called perihaematomal oedema) and how it affects recovery. Researchers will follow 500 people with a brain bleed to see if the swelling leads to worse disability. The goal is to better understand this swelling so fut…

This study looks at why some people keep their thinking skills after a stroke while others don't. Researchers will interview 450 adults who had a stroke and had a brain scan. They want to see how things like education, race, and income affect memory and attention over time.

This study is a registry that gathers existing medical information from up to 40,000 people who have had surgery for brain conditions like stroke, aneurysm, or abnormal blood vessels. Researchers will analyze this data to better understand which treatments work best and to predic…

This study watches how stroke survivors move their arms during everyday activities. Researchers will measure hand movements, joint motion, and wrist distance over time. The goal is to link these real-world movements with standard recovery tests. No treatment is given—only observa…

This study enrolls 500 people with cerebral small vessel disease (CSVD), a condition that damages small blood vessels in the brain and can lead to stroke or dementia. Participants undergo genetic testing to see if their disease is inherited, and researchers track their health for…

This study tests whether a new wearable device that uses ultrasound and light can safely and easily monitor blood flow in the brains of people who have had a stroke. Researchers will also include healthy older adults and people with dementia, depression, or delirium to compare re…

This study explores why some people recover language after a stroke better than others. Researchers will use genetic tests and MRI brain scans in 90 adults aged 40-90 who have had a stroke. The goal is to find markers that predict recovery, which could lead to better treatments f…

This study explores whether combining prism adaptation training (wearing special glasses that shift vision) with mild electrical stimulation can improve spatial neglect and walking problems after a stroke. Researchers will measure changes in pointing accuracy, brain activity, and…

This study looks at whether a rapid genetic test can help doctors pick the best antiplatelet medication for people who have had a minor stroke or a high-risk transient ischemic attack (TIA). About 200 participants will provide a cheek swab sample during their hospital stay, and r…

This study tests whether a live video call between a neurologist and paramedics can improve the accuracy of stroke diagnosis before the patient reaches the hospital. About 512 adults with suspected stroke will take part. The goal is to see if video assistance helps identify more …

This study follows 130 patients with severe brain injuries (from stroke, trauma, or lack of oxygen) who are in a coma or minimally conscious state. Researchers will use brain scans, EEG, and other tests to find clues that might predict if and when a patient will regain consciousn…

This study is testing a new way to help people who have had a stroke regain arm movement. The method uses a brain stimulation technique called TMS, timed precisely based on brain signals measured by a special light-based sensor. The goal is to see if this approach can improve bra…

This study looks at whether people who have a blood clot in the lungs (pulmonary embolism) and also have a small hole in their heart (called a PFO) are more likely to have a stroke. Researchers will use brain scans and ultrasound to check for these conditions. About 256 adults wi…

This study aims to learn more about how young adults (ages 18-55) recover from a stroke. Researchers will collect detailed health information and samples from 100 participants to see how practical this approach is and what factors like age, lifestyle, and biology affect recovery.…

This study explores whether combining non-invasive brain and spinal cord stimulation during a thinking-and-movement task can improve sensation, movement, and thinking in people who have had a stroke or cervical spinal cord injury. About 45 adults will take part, including healthy…

This study is looking at whether certain DNA changes can help predict the risk of brain injury in older adults undergoing a heart valve replacement procedure called TAVR. Researchers will measure DNA methylation in blood samples before and after the procedure and compare it to br…

This study tests a new walking training method for people who have had a stroke. It uses a split-belt treadmill (where each leg moves at a different speed) along with resistance and real-time feedback (like sounds or visuals) to help the weaker leg push off more strongly. The goa…

This study looks at how the brain and spinal cord change after a stroke. Researchers will use MRI scans to compare stroke patients with healthy volunteers. The goal is to find patterns that help predict recovery and understand why symptoms vary. About 35 people will take part.

This study looks at how placebos (fake treatments) work in the brains of people who have had a stroke. Researchers want to see if placebos can change brain activity and help improve movement. About 56 adults with arm weakness from a chronic stroke will take part. The goal is to u…

This study tests whether using remote-controlled CT scans with live video guidance from a stroke expert team can speed up treatment for stroke patients at smaller hospitals. About 52 adults with suspected stroke within 24 hours of symptoms will take part. The goal is to see if th…

This study looks at how the brains of 25 stroke patients with weak hand muscles work when they do mirror movements. Researchers use a special brain scanner to measure activity. The goal is to learn more, not to test a treatment.

This study uses powerful 3T and 7T MRI scanners to create detailed maps of how the brain reorganizes after a stroke. Researchers will scan 100 stroke patients and 10 healthy volunteers to understand connections between brain activity and movement. The goal is to improve future tr…

This study will video-record occupational therapy sessions for adults recovering from stroke or spinal cord injury. Researchers want to understand exactly what therapists do to help patients improve arm and hand function. By analyzing these videos, they hope to create a toolkit t…

This study looks at whether a new test called the Ad-AHA Stroke accurately measures how stroke survivors use both hands together in daily life. Researchers will compare test scores with real-world data from wrist-worn sensors worn for three days at home. The goal is to see if the…

This study looks back at medical records of 2600 stroke patients who received clot-busting medication between 4.5 and 24 hours after their stroke started. The goal is to see how many had good recovery (able to live independently) despite the delayed treatment. It does not test a …

This study tests whether a modified cardiac rehabilitation program can improve physical and emotional recovery in people who have had a stroke. Researchers will enroll 76 adults aged 18-80 who had a stroke at least 6 months ago and have some leg weakness. The goal is to see if de…

This study looks at how stroke affects walking efficiency. Researchers will test a new method to pinpoint why walking is harder for some people. 18 adults with chronic stroke will walk on a treadmill to compare this new measure with standard energy-use tests.

This study explores whether a brain imaging technique called fMRI neurofeedback can help people who have had a stroke improve their reading. Participants will practice controlling their own brain activity using real-time feedback, aiming to boost activity in the language side of …

This study looks at how using arm support (like a cane or walker) changes the way people who have had a stroke walk. About 34 adults with stroke will walk on a special treadmill with no support, one-arm support, or two-arm support. The goal is to learn which support method helps …

This study looks at how a gentle electrical current applied to the brain (called tACS) affects movement in people who had a stroke more than 6 months ago. Researchers will test two different frequencies and a placebo to see which works best. They will use brain scans (MRI) and br…

This study aims to better understand where blood clots come from in people who have had a stroke. Researchers will use a special PET scan that can detect active platelets (clotting cells) in the body. About 120 adults who recently had a stroke will be scanned to see if this metho…

This study is testing whether a quick, painless eye scan called OCTA can spot signs of brain diseases like stroke and bleeding. Researchers will compare scans from 50 people with brain conditions and healthy volunteers. The goal is to gather early data to support larger studies, …

This study looks at how deep brain stimulation (DBS) changes movement in people with conditions like Parkinson's disease, essential tremor, or stroke. Researchers will test 60 patients who are already scheduled for DBS surgery. During the procedure, they will add a temporary elec…

This study looks at how tiny blood vessel damage in the brain affects thinking skills in older adults. Researchers will use EEG to measure brain activity and test if personalized brain training or gentle electrical stimulation can help. The goal is to find better ways to detect a…

This study looks at how the diaphragm—the main muscle for breathing—changes in people who have had a stroke and have weakness on one side of the body. Researchers will use ultrasound to measure diaphragm movement and thickness, and compare it to breathing muscle strength. The goa…

This study is for adults with psoriasis who want to help researchers understand if psoriasis increases the risk of heart disease. The goal is to find early warning signs of heart problems by using heart scans and blood tests. Participants will be followed over time to track heart…

This study is looking at whether certain genetic variations (in the annexin A2 gene) are linked to a higher risk of stroke in young adults whose stroke cause is unknown. Researchers will compare blood samples from 240 people who have had a stroke with no clear cause. The goal is …

This study looks at whether backward walking training can improve walking and balance in Veterans who have had a stroke. Researchers will compare two different amounts of training (18 vs. 27 sessions) and use brain scans to see how the brain changes. The goal is to find out which…

This study explores whether delivering magnetic pulses to the brain at moments when it is most ready to send signals to the hand can improve recovery after stroke. About 37 people who had a stroke at least 6 months ago and still have hand weakness will take part. Researchers will…

This study tests a new ultrasound device that can continuously monitor blood flow in the brains of sick and premature babies. The goal is to see if this non-invasive tool works well and provides useful information for doctors. About 180 infants with conditions like heart defects,…

This study is testing whether a new digital test battery, called Mindmore Distance, can accurately measure thinking and memory skills in people with neurological conditions like traumatic brain injury, stroke, multiple sclerosis, Parkinson's disease, epilepsy, or brain tumor. Res…

This study uses advanced MRI scans to look at brain and spinal cord activity in people who have weakness on one side after a stroke. Researchers want to understand which nerve pathways the brain uses to move the shoulder. The goal is to learn more about how the brain adapts after…

This study is for 150 adults getting a HeartMate 3 heart pump. Researchers will collect data from the pump to see if it can predict problems like bleeding, infection, or stroke. The goal is to learn how pump information relates to quality of life and health outcomes.

This study looks at how changes in brain blood flow affect breathing stability during sleep in healthy adults. Participants will sleep under normal oxygen and low-oxygen conditions to measure breathing reflexes. The goal is to understand the link between brain blood flow and brea…

This study is for adults with muscle, joint, or nerve problems who have been given a home exercise program by their doctor. Researchers want to understand why some people follow their home exercises and others don't. They will look at factors like pain, mood, and daily life to he…

This observational study looks at whether the settings on a breathing machine (like pressure and power) are linked to how severe a person's brain injury is. It includes 19 adults with brain injuries from stroke, trauma, or bleeding who need a breathing machine. The goal is to see…

This study looks at 1,000 people having open-heart surgery to see if a standard heart test (ECG) can tell who is likely to form dangerous blood clots that cause stroke. During surgery, a small pouch in the heart (the left atrial appendage) is closed and often removed. Researchers…

This study looks at 500 people who have had a stroke and also have atrial fibrillation (an irregular heartbeat). Even with blood thinners, some still have strokes. Researchers want to find out why by checking heart function, blood markers, and heart imaging. The goal is to better…

This study looks at how fear of movement (kinesiophobia), balance, and fear of falling are connected in people recovering from a stroke. Researchers will measure these factors using surveys and balance tests in 138 stroke patients. The goal is to better understand these relations…

This study looks at how taking multiple medications affects the health of elderly people with chronic diseases like heart disease, diabetes, and high blood pressure. Researchers will survey 2000 patients aged 65 and older in Shaanxi Province, China, over two years. The goal is to…

This study looks at how stroke changes the way people move their arms when walking. Researchers will measure brain activity and muscle patterns in 84 people (some who had a stroke and some healthy) to understand why arm swing is different after a stroke. The goal is to gather kno…

This study is testing a new, non-invasive wearable patch with a microphone that records swallowing sounds in people who have trouble swallowing after a stroke. The goal is to see if the sound patterns can help doctors diagnose swallowing problems more easily. About 50 adults aged…

This early study tests whether a brain implant can help people with severe paralysis from conditions like ALS, stroke, or spinal cord injury control devices using their thoughts. Three adults will have a small sensor placed on the brain's surface to decode signals for typing text…

This study looks at whether thinking about your body movements (internal focus) or an object outside your body (external focus) helps people who had a stroke stand up more evenly from a chair. Twenty adults who had a stroke at least six months ago will try both methods. The goal …

This study looks for brain signals (biomarkers) that can track and predict how well stroke patients recover walking ability. Researchers will use a mobile brain/body imaging device while patients walk with a robotic exoskeleton. The goal is to find markers that doctors can use to…

This study follows 500 healthy adults from Hong Kong to see if COVID-19 vaccines have any impact on brain health over time. Participants will get MRI brain scans to look for changes in blood vessels and brain structure. The goal is to provide clear, evidence-based information to …

This study is testing whether a special MRI of the heart can help doctors decide which stroke patients need a small heart monitor implant. About 100 adults who had a stroke with no clear cause will get a heart MRI and a monitor. The goal is to see if scar tissue in the heart's up…

This study looks at how often fatigue occurs after a first stroke and what factors—like pain, mood, sleep, or physical ability—might make it worse. About 107 adults who had a stroke at least three months ago will answer questionnaires and do simple tests. The goal is to help doct…

This study looks at how brain stimulation combined with stepping practice affects leg skill learning in healthy adults and people with chronic stroke. Researchers will measure changes in stepping speed and brain activity after five sessions. The goal is to better understand how t…

This study is testing whether wearable body sensors can accurately monitor and measure recovery in people recovering from a stroke during inpatient rehabilitation. Researchers will use the sensor data to estimate how well patients are doing and compare it to standard clinical tes…

This study aims to understand how a protein called BD-tau, which is released into the blood when the brain is injured, changes over time in people having a stroke. Researchers will take blood samples every hour for 48 hours from 100 adults with acute ischemic stroke. The goal is …

This study looks at whether combining ultrasound with artificial intelligence can help doctors quickly identify brain bleeding in people having a stroke. About 500 adults with stroke symptoms will get a non-invasive ultrasound scan within 48 hours, and AI will compare the results…

This study aims to find biological markers that can predict which stroke survivors will improve their walking speed with high-intensity interval training (HIIT). Researchers will measure blood lactate levels and brain activity in 55 Veterans with chronic stroke. The goal is to bu…

This study tests better ways to recruit a wider range of people into stroke rehabilitation research, especially women and those with language problems after a stroke. Researchers will compare a new recruitment method to the usual one across several Canadian hospitals. The goal is…

This study follows 140 working-age stroke survivors in France to find out what factors help or hinder their return to work. Researchers will look at medical details, personal beliefs, and workplace support. The goal is to create better rehab and job reintegration plans for stroke…

This early study looks at whether a non-invasive device that stimulates a nerve in the ear (taVNS) can change brain activity and certain genetic markers in people who had a stroke within the past month. About 44 participants with arm weakness will receive either real or fake stim…

This pilot study looks at how Botox injections affect the muscles, tendons, and nerves in the foot of people who had a stroke and developed a tight, twisted foot (equinovarus). Researchers will use special ultrasound and movement tests to measure changes over time. The main goal …

This study is testing a new questionnaire called the Pressure Relief Frequency Scale (PReFS) to see if it can reliably help wheelchair users with neurologic disorders (like spinal cord injury, stroke, or traumatic brain injury) decide how often they need to relieve pressure. Rese…

This study looks at how the brain talks to muscles in people who have had a stroke. Researchers will use gentle, non-invasive brain stimulation and measure brain and muscle activity while participants squeeze a device with their weak hand. The goal is to see if stimulation can im…

This study is building a nationwide registry of people who have had a stroke and still have symptoms. The goal is to connect them with researchers working on new ways to improve recovery. Up to 60,000 adults aged 18 and older will join this registry, which does not involve any tr…

This study looks at how hospitals in Villavicencio, Colombia, manage stroke cases. Researchers will review medical records from 100 adults diagnosed with stroke to see how quickly they receive care and whether treatments follow best practices. The goal is to find ways to improve …

This study is testing a special glove with sensors to see how well it measures touch and thinking problems in people who have had a stroke. The goal is to make sure the glove works safely and reliably, so doctors can use it to improve robotic rehab for the arm and hand. About 126…

This study compares a pressure-sensitive smart insole (Ceriter Stride One) to a high-tech lab system (GRAIL) for measuring walking patterns in 30 people with stroke, spinal cord injury, or brain injury. Participants walk on a treadmill while wearing the insoles, and researchers c…

This study looks at a layer of tissue in the lower back (thoracolumbar fascia) in people who had a stroke at least 6 months ago. Researchers want to see if its thickness is related to balance, trunk control, flexibility, and daily independence. About 70 participants aged 40-70 wi…

This study will follow 5,000 people who have had a brain aneurysm treated with new endovascular devices. The goal is to see how safe and effective these devices are, and to find out what factors, like smoking, might cause the aneurysm to come back. The study is purely observation…

This study explores how brain stimulation can help people who have had a stroke move faster. Researchers will first test healthy volunteers to map brain areas that control movement speed, then apply targeted stimulation to stroke patients. The goal is to understand the brain circ…

This study is collecting information from 200 people with cerebral palsy, multiple sclerosis, stroke, fibromyalgia, or similar nerve disorders to see how the EXOPULSE suit affects their balance and walking over time. Participants will be followed during routine care, and research…

This study tests whether a virtual reality (VR) walking program is practical and well-liked by stroke patients and their therapists. About 40 adults who had a stroke will do personalized VR walking exercises twice a week for 4 weeks. The goal is to see if the program can be easil…

This study looks at a small muscle in the leg called the plantaris and how it contributes to ankle tightness in children. About 42 kids aged 4-17 having ankle surgery will take part. During surgery, doctors will measure ankle movement before and after releasing the plantaris to s…

This study tests a wearable device called Neuralert that monitors hospital patients at high risk for stroke. The device is worn on both arms and sends alerts if it detects signs of a stroke. The goal is to see if it can identify strokes faster than current methods. About 50 adult…

This study is testing a noninvasive treatment that uses mild electrical pulses on the skin over the spine to help people with stroke or spinal cord injury regain arm and hand function. Researchers will measure changes in nerve activity and movement in 30 adults aged 18-75. The go…

This study looks at whether giving magnetic brain stimulation at the right moment in your natural brain rhythm can make it work better for improving arm and hand movement. Researchers will test healthy adults and people who had a stroke at least six months ago. The goal is to lea…

This study looks at why stroke survivors' muscles tire faster during activities like walking. Researchers will measure blood flow to leg muscles during exercise and test a safe, non-invasive technique called ischemic conditioning to see if it can reduce fatigue. The study involve…

This study follows 400 stroke patients in rehabilitation units to understand how walking and balance improve over six months. Researchers will measure walking ability and balance using simple tests. No new treatments are given—the goal is to learn more about natural recovery patt…

This study is creating a large collection of blood samples from 1,000 people with atrial fibrillation (an irregular heartbeat) and stroke. Researchers will analyze the DNA and plasma to better understand the genetic causes of these conditions. The goal is to find new targets for …

This study looks at whether low magnesium levels in the blood are linked to memory, thinking, and other cognitive problems after a stroke. Researchers will measure magnesium and cognitive function in 80 stroke patients over time. The goal is to understand if magnesium deficiency …

This study uses high-resolution and high-speed cameras to take detailed pictures of the eye. The goal is to see tiny structures that regular eye exams miss, which could help doctors better understand diseases like glaucoma, macular degeneration, and diabetes-related eye problems.…

This study looks at whether a training program that mixes mental tasks with physical exercises can improve thinking and movement in people who have had a stroke or have Moyamoya disease. Researchers will measure brain activity during these tasks using a special light-based scanne…

This study looks at how memory and thinking problems after a stroke affect a person's ability to relearn walking. Researchers will use walking tests, thinking assessments, and brain scans in 65 older adults who had a stroke at least 6 months ago. The goal is to find better ways t…

This study looks at how stroke changes the way the spinal cord handles sensory signals. Researchers will stimulate nerve roots in the neck during surgery and measure muscle and brain responses. The goal is to understand these changes better, not to treat them directly. Participan…

This study looks at how the brain controls arm movement after a stroke and how rehabilitation therapy changes those brain pathways. Researchers will enroll 50 people who had a stroke 3 to 6 months ago and have moderate to severe arm weakness. Participants will either receive 30 h…

This study follows 150 people who recently had a stroke to see how their walking ability recovers over time. Researchers will measure walking speed and distance, and look at how patients develop new ways to move. The goal is to create better rules for predicting and improving rec…

This study looks at how a single session of exercise can temporarily reduce sensitivity to pain—a phenomenon called exercise-induced hypoalgesia—in both healthy adults and stroke survivors who do not currently have pain. Researchers will measure pain thresholds before and after a…

This study checks if a hand laterality task (deciding if a picture shows a left or right hand) is a valid tool for stroke patients. About 30 adults who have had a stroke will complete reaction time and hand-judgment tasks. The goal is to see how well the test measures brain funct…

This study tests whether using gentle muscle vibrations can help the brain form new connections after a stroke or traumatic brain injury. Researchers will measure brain and spinal cord activity in 56 participants before and after a 5-week vibration treatment. The goal is to under…

This study aims to understand how a touch signal moves from the finger, through the nerves, and into the brain. Researchers will test 60 people, including young adults and stroke survivors, by applying gentle forces to the finger and using brain scans (fMRI). The goal is to learn…

This study tests a new virtual reality system that combines mirror therapy with fun, game-like activities to help people recover arm movement after a stroke. Researchers will enroll 172 participants, including both healthy volunteers and stroke survivors, to see if the system is …

This study aims to see if brain activity recorded from the surface of the brain can be used to decode imagined Mandarin Chinese speech, including tones, without the person speaking out loud. About 50 adults with conditions like epilepsy, brain tumors, or stroke who are already un…

This study looks at how to best measure and treat a condition called neglect that can happen after a stroke, where people ignore one side of their world. Researchers will test a treatment that combines repetitive task practice with a gentle brain stimulation technique called tran…

This study tracks 350 adults who had a severe stroke caused by a blocked large artery. Researchers want to see how well a procedure called endovascular thrombectomy (which removes the clot) works outside of strict clinical trials. The goal is to find what helps or hinders recover…

This study aims to collect detailed information from 70 stroke patients to build a 'digital twin'—a computer model that reflects their movement patterns and recovery. By tracking daily activities, movement, and genetic data over time, researchers hope to better understand how dif…

This study aims to find reliable tests that can predict how well a person's arm will recover after a stroke. Researchers will use brain scans and a safe, non-invasive brain stimulation technique on about 657 stroke patients within days of their stroke. The goal is to create bette…

This study aims to understand how two mental practice techniques—imagining movements and watching others perform movements—affect muscle activity in stroke survivors. Researchers will measure electrical signals in arm and hand muscles of 28 participants during these exercises to …