Brain zaps and electric gloves: new hope for stroke survivors with severe hand paralysis?
NCT ID NCT03870672
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether combining two non-invasive therapies can improve hand function in people who had a stroke at least six months ago and have severe arm weakness. The therapies are a brain stimulation technique called rTMS and a device that uses electrical stimulation to open the weak hand, controlled by a glove on the strong hand. Researchers will compare three treatment combinations to see which works best and for whom.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
repetitive transcranial magnetic stimulation (rTMS) and contralaterally controlled functional electrical stimulation (CCFES)
What this could lead to
If successful, this could lead to a new rehabilitation therapy that helps people with severe hand weakness after a stroke regain more use of their affected arm.
What could go wrong
This is an early-stage trial with only 72 participants, so results may not apply to everyone. The improvements may be small or not last long, and brain stimulation can cause discomfort or headache.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Lerner Research Institute; Cleveland Clinic Foundation
RECRUITINGCleveland, Ohio, 44195, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••