Blood's tiny messengers may expose hidden brain injury

NCT ID NCT07769294

NEW Not yet recruiting Knowledge-focused Sponsor: Roberto Furlan Source: ClinicalTrials.gov ↗

First seen Aug 17, 2026 · Last updated Aug 17, 2026

Summary

This study investigates whether tiny particles called extracellular vesicles, released by brain cells into the blood, can serve as reliable markers of nerve damage in people with multiple sclerosis or stroke. Researchers will measure these particles in blood samples from 60 participants to see if they reflect ongoing brain injury better than current tests. The goal is to develop a simpler way to monitor neurodegenerative processes, which could speed up the development of new treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Measurement of neural extracellular vesicles in blood plasma (no drug or treatment given)
What this could lead to: If successful, this could lead to a simple blood test to monitor nerve damage in multiple sclerosis and stroke, helping to develop new treatments faster.
What could go wrong: This is an early exploratory study with a small number of participants. The biomarkers may not prove specific or reliable enough for clinical use, and the technology is still being developed.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

ischemic stroke multiple sclerosis relapsing-remitting multiple sclerosis stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MULTIPLE SCLEROSIS STROKE

More trials for these conditions

Other studies related to the condition(s) this trial covers.