Could a Clot-Removing device shield the Brain's thinking power after stroke?

NCT ID NCT05531461

Recruiting now Disease control Sponsor: Rapid Medical Source: ClinicalTrials.gov ↗

First seen Aug 12, 2026 · Last updated Aug 13, 2026 · Updated 1 time

Summary

This study looks at whether successfully restoring blood flow in the brain using the Tigertriever device, a tool that removes clots during a stroke, may also help protect cognitive abilities like memory and attention. Researchers will follow 424 adults aged 18 to 75 who had a large-vessel occlusion stroke and were treated with Tigertriever as the first-line therapy. They will compare thinking and memory scores taken shortly after treatment with those at 180 days to see if good blood flow restoration is linked to better cognitive outcomes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Tigertriever, a stent-retriever device used to remove blood clots in the brain during a stroke
What this could lead to: If successful, this could show that using Tigertriever to restore blood flow after a stroke may help preserve or improve cognitive function, such as memory and thinking.
What could go wrong: This is an observational study, so it cannot prove cause and effect. Cognitive improvement may vary widely, and results may not apply to all stroke patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for LARGE VESSEL OCCLUSION STROKE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

large artery stroke stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

STROKE

Contacts and locations

Locations

Corewell Health Research Institute
RECRUITING

Grand Rapids, Michigan, 49503, United States
University of California
RECRUITING

Los Angeles, California, 90095, United States
Westchester Medical Center
RECRUITING

New York, New York, 10595, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.