AI picks the right therapy for Stroke-Linked reading loss
NCT ID NCT07209488
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a computer model can predict which reading treatment works best for people who developed dyslexia after a stroke. Twelve participants will each try two different therapies—phonomotor treatment and semantic feature analysis—for 60 hours each. The goal is to see if the model's recommended therapy leads to better reading improvement.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 12 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Dec 2025
- Expected to finish
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Sep 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 85 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Fluent in English as a first language pre-stroke by self report. * Normal or corrected-to-normal vision. * Normal or aided hearing. * Left hemisphere ischemic or hemorrhagic stroke (as verified by a structural brain scan). * Impaired reading as confirmed by significant impairment in the Basic Skills cluster of the Woodcock Reading Mastery Test - III. Exclusion Criteria: * Diagnosed pre-stroke neurological disease affecting the brain other than left hemisphere stroke. * Severe apraxia of speech (determined by consensus judgment among speech-language pathologists). * History of learning disabilities such as developmental dyslexia or current self-reported major psychiatric disorders. * Inability to undergo, or provide a copy of, a post-stroke brain imaging scan.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
3 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Florida State University
RECRUITINGTallahassee, Florida, 32306, United States
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Johns Hopkins University School of Medicine
RECRUITINGBaltimore, Maryland, 21287, United States
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Kessler Foundation
RECRUITINGWest Orange, New Jersey, 07052, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Effects of transcranial direct current stimulation and pelvic proprioceptive neuromuscular facilitation on trunk control, balance and functional mobility in stroke patients
- Correlation of visual and motor deficits in stroke patients
- Pilot study on the effects induced by an electromyographic-controlled functional electrical stimulator (FitFES) for upper limb rehabilitation in post-stroke patients
- Brazilian version of a behavior change intervention to support healthy lifestyle adoption after stroke - iVIDAVC: protocol for a pilot randomized study
- Determination of efficacy of sustained motor contraction generated using StimWave peripheral nerve stimulator
- Can a PET tracer reveal hidden brain inflammation?