New care bundle aims to save lives after brain hemorrhage

NCT ID NCT06429332

Recruiting now Disease control Sponsor: Region Skane Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a structured care bundle—including rapid blood pressure control, reversal of blood thinners, and management of fever and blood sugar—can improve outcomes for people with a brain bleed. About 3500 adults in Sweden and Australia will receive either the care bundle or standard care. The goal is to see if this approach reduces disability and improves quality of life at 3 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: care bundle (blood pressure lowering, anticoagulation reversal, fever and glucose management)
What this could lead to: If successful, this care bundle could become a standard treatment to improve recovery and reduce disability after a brain bleed.
What could go wrong: This is a large trial, but the care bundle involves multiple steps, so it may be hard to implement consistently. Results may not apply to all settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cerebrovascular disorder intracerebral hemorrhage stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CEREBROVASCULAR DISEASE INTRACEREBRAL HAEMORRHAGE INTRACEREBRAL HEMORRHAGE INTRAVENTRICULAR HEMORRHAGE STROKE

Contacts and locations

Locations

Akademiska Sjukhuset Uppsal
RECRUITING

Uppsala, 75185, Sweden
Avezzano Ospedale SS. Filippo e Nicola
RECRUITING

Avezzano, 67051, Italy
Azienda Ospedaliera Santa Maria della Misericordia Perugia
RECRUITING

Perugia, 06129, Italy
Blekingesjukhuset
RECRUITING

Karlskrona, Sweden
Blekingesjukhuset Karlskrona
RECRUITING

Karlskrona, 371 41, Sweden
Capio St Görans Sjukhus
RECRUITING

Stockholm, 112 81, Sweden
Centrallasarettet Växjö
RECRUITING

Vaxjo, Sweden
Centralsjukhuset Karlstad
RECRUITING

Karlstad, 651 85, Sweden
Centralsjukhuset Kristianstad
RECRUITING

Kristianstad, Sweden
Citta di Castello Ospedale Città di Castello
RECRUITING

Città di Castello, 06012, Italy
Danderyds sjukhus
RECRUITING

Stockholm, 182 88, Sweden
Gubbio Ospedale di Gubbio e Gualdo Tadino
RECRUITING

Gubbio, Italy, Italy
Hallands sjukhus Varberg
RECRUITING

Varberg, 43237, Sweden
Hamilton General Hospital
RECRUITING

Hamilton, Ontario, L8L 2X2, Canada
Health Sciences North/Health Sciences North Research Institute
RECRUITING

Greater Sudbury, Ontario, P3E 5J1, Canada
Helsingborgs Lasarett
RECRUITING

Helsingborg, Sweden
Hong Kong University Hospital
RECRUITING

Hong Kong, Hong Kong
Hässleholms Sjukhus
RECRUITING

Hässleholm, Sweden
Höglandssjukhuset i Eksjö
RECRUITING

Eksjö, 575 81, Sweden
Karolinska Universitetssjukhuset Huddinge
RECRUITING

Huddinge, Sweden
Karolinska Universitetssjukhuset Solna
RECRUITING

Stockholm, 171 76, Sweden
Kungälvs sjukhus
RECRUITING

Kungälv, 442 83, Sweden
Landspitali University Hospital
RECRUITING

Reykjavik, 105, Iceland
Lasarettet i Enköping
RECRUITING

Uppsala, 751 85, Sweden
Ljungby Lasarett
RECRUITING

Ljungby, 341 35, Sweden
Länssjukhuset Kalmar
RECRUITING

Kalmar, 391 85, Sweden
Länssjukhuset Ryhov
RECRUITING

Jönköping, 551 85, Sweden
Länssjukhuset Sundsvall
RECRUITING

Sundsvall, Sweden
Monash Medical Centre
RECRUITING

Clayton, 3168, Australia
Mölndals Sjukhus
RECRUITING

Mölndal, 431 80, Sweden
National University of Malaysia Hospital
RECRUITING

Kuala Lumpur, 56000, Malaysia
Norra Älvsborgs Länssjukhus
RECRUITING

Trollhättan, 461 85, Sweden
Norrlands Universitetssjukhus
RECRUITING

Umeå, Sweden
Oskarshamn Sjukhus
RECRUITING

Oskarshamn, 572 28, Sweden
Ottawa Hospital Research Institute
RECRUITING

Ottawa, Ontario, K1Y 4E9, Canada
Region Skåne, Skåne University Hospital in Malmö, Department of Neurology
RECRUITING

Malmö, 20502, Sweden
Roma Policlinico Gemelli
RECRUITING

Roma, 00136, Italy
Royal Adelaide Hospital
RECRUITING

Adelaide, 5000, Australia
Sahlgrenska Universitetssjukhuset
RECRUITING

Gothenburg, 413 45, Sweden
Skaraborgs Sjukhus Skövde
RECRUITING

Skövde, 541 85, Sweden
Skåne University Hospital Lund
RECRUITING

Lund, Sweden
Skåne University Hospital Lund Neurosurgery dept
RECRUITING

Lund, Sweden
Södersjukhuset
RECRUITING

Stockholm, 118 83, Sweden
The George Institute for Global Health
NOT_YET_RECRUITING

Sydney, NSW 2000, Australia
The University of Oklahoma Health
RECRUITING

Oklahoma City, Oklahoma, 73126-0901, United States
Univeristetssjukhuset Linköping
RECRUITING

Linköping, 581 85, Sweden
Universitetssjukhuset Örebro
RECRUITING

Örebro, 701 85, Sweden
Universiti Putra Malaysia Hospital
RECRUITING

Serdang, 43400, Malaysia
Värnamo sjukhus
RECRUITING

Värnamo, 331 85, Sweden
Västerås
RECRUITING

Västerås, 721 89, Sweden
Västmanlands sjukhus Köping
RECRUITING

Köping, 731 81, Sweden
Ystads lasarett
RECRUITING

Ystad, Sweden
Östersunds Lasarett
RECRUITING

Östersund, Sweden
Östra Sjukhuset
RECRUITING

Gothenburg, 41685, Sweden

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