Could a pill trio supercharge stroke rehab?
NCT ID NCT07588932
First seen Jun 24, 2026 · Last updated Jul 15, 2026 · Updated 4 times
Summary
This early-phase trial aims to see if taking a combination of three common drugs (Telmisartan, Metformin, and Cilostazol) can help chronic stroke survivors gain more movement in their arms and hands during robot-assisted therapy. Fifty adults who had an ischemic stroke at least six months ago and have moderate to severe arm impairment will participate. The study will compare motor gains between those taking the drugs plus rehab and historical data from rehab alone.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Telmisartan, Metformin, and Cilostazol (a combination of blood pressure, diabetes, and blood flow medications)
- What this could lead to
- If it works, this could point toward a way to improve arm and hand function in people who have had a stroke, making rehabilitation more effective.
- What could go wrong
- This is a very early (Phase 1) trial with only 50 people, so results may not apply widely. The drug combo may cause side effects or not improve recovery more than rehab alone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Spaulding Rehabilitation Hospital
RECRUITINGCharlestown, Massachusetts, 02129, United States
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Other studies related to the condition(s) this trial covers.
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