Spaulding Rehabilitation Hospital

This study is for adults aged 18–80 with chronic spinal cord injury who can already walk a little. It combines short periods of low oxygen, spinal cord stimulation, and walking practice to see if it can improve walking speed and endurance. The goal is to help people walk better, …

This study tests whether combining short bursts of low oxygen, spinal cord stimulation, and walking practice can improve walking for people with chronic spinal cord injury. About 60 adults with some remaining leg function will take part. The goal is to see if this approach speeds…

This study tests a new non-drug approach for fibromyalgia that combines cognitive training with acupuncture. Researchers want to see if this helps the brains of patients and clinicians work in sync, which may improve pain relief. About 100 adults with fibromyalgia will take part.…

This study tests if shockwave therapy can reduce pain and improve knee function in athletes who developed osteoarthritis after ACL reconstruction. About 70 participants will receive the treatment and be monitored for changes in pain, movement, and joint health. The goal is to eas…

This study tests a non-invasive device that stimulates a nerve in the ear, combined with support therapy, to help people with functional dyspepsia (chronic stomach pain and discomfort). The goal is to reduce gut-related anxiety and improve digestion. 80 adults aged 18-65 will par…

This study tests whether wearing a ring sensor and seeing your arm activity on a smartphone app can encourage stroke survivors to use their affected arm more during everyday tasks. About 50 chronic stroke survivors (more than a year after their stroke) will wear the sensors and u…

This study tests a wrist-worn sensor system called StrokeWear to help chronic stroke survivors use their weaker arm more in daily life. 32 participants will either use the sensor with a home exercise program or follow standard home exercises alone. The goal is to see if the senso…

This early-phase study tests whether MDMA-assisted therapy can reduce pain and improve the bond between patients and therapists for people with fibromyalgia. Twenty adults with fibromyalgia will receive two therapy sessions with MDMA while their brain activity is scanned. The goa…

This study tests whether a painless brain stimulation technique (tDCS plus ultrasound) can reduce chronic pain in people with carpal tunnel syndrome. About 95 adults with long-term wrist pain will receive either real or fake stimulation to see if it lowers their pain scores. The …

This study tests a wrist-worn sensor system called StrokeWear to help people who have had a stroke use their weaker arm more in daily life. About 88 participants who had a stroke 1 to 6 months ago will either use the sensor with a home exercise program or follow standard care. Th…

This study tests if a portable brain stimulation device (tDCS) used at home, along with sensory training, can reduce phantom limb pain in people with amputations. About 290 adults who feel pain at least once a week will either use the device plus training or continue their usual …

This study tests a camera system that watches how stroke survivors move their arms during robot-assisted therapy. The camera uses smart software to detect bad posture and give feedback. Researchers want to see if this setup works as well in small groups as it does in one-on-one s…

This observational study looks at how the brains of romantic partners communicate differently than those of strangers. Using EEG to record brain activity from two people at the same time, researchers will compare couples versus strangers both in person and remotely. The goal is t…

This study looks at how placebos (fake treatments) work in the brains of people who have had a stroke. Researchers want to see if knowing you are getting a placebo changes brain activity and helps with recovery. About 56 adults with arm weakness from a chronic stroke will take pa…

This study looks at how the Q-Collar, a device worn around the neck, changes blood flow to the brain during rest and exercise. Twenty healthy adults aged 18 to 30 will complete two sessions—one with the collar and one without—while doing standing tests, breathing exercises, and b…

This study looks at how breathing low oxygen for short periods (intermittent hypoxia) might help people with chronic spinal cord injury improve walking and muscle strength. Researchers want to understand the brain and nerve changes behind any recovery. The study involves 44 adult…

This study tests whether six weeks of slow, resistive yoga breathing (Ujjayi) can improve breathing patterns, lung function, and sleep quality in 20 adults aged 18-60 with spinal cord injuries. Participants will practice the breathing technique at home and complete lab tests befo…