Could MDMA help ease fibromyalgia pain? early trial launches
NCT ID NCT06066853
First seen Jun 24, 2026 · Last updated Jun 30, 2026 · Updated 3 times
Summary
This early-phase study tests whether MDMA-assisted therapy can reduce pain in 20 adults with fibromyalgia. Participants receive MDMA combined with psychotherapy and undergo brain scans to see how the drug affects pain and the bond between patient and therapist. The goal is to understand the brain mechanisms behind any pain relief, not yet to prove a treatment works.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
MDMA (combined with psychotherapy)
What this could lead to
If it works, this could point toward a new treatment option for fibromyalgia pain that also improves the patient-therapist relationship.
What could go wrong
This is a very early, small trial with only 20 people. It is designed mainly to study brain mechanisms, not to prove effectiveness, and MDMA has known risks like increased heart rate and psychological distress.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Massachusetts General Hospital
RECRUITINGCharlestown, Massachusetts, 02114, United States
Contact Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••