Could a probiotic soothe fibromyalgia pain in young people?
NCT ID NCT07738926
First seen Jul 31, 2026 · Last updated Jul 31, 2026
Summary
This study tests whether a daily probiotic supplement, Bifidobacterium adolescentis PRL2019, can reduce pain in young people aged 9 to 25 with juvenile fibromyalgia, a condition marked by widespread musculoskeletal pain. Participants will take the probiotic or a placebo for 12 weeks, then switch, allowing each person to serve as their own comparison. The trial measures changes in pain scores and other symptoms to see if gut bacteria modulation might offer relief.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Bifidobacterium adolescentis PRL2019 (probiotic supplement)
- What this could lead to
- If effective, this probiotic could offer a simple, well-tolerated option to reduce pain and improve quality of life for young people with fibromyalgia.
- What could go wrong
- This is a small early-stage trial, and the supplement may not outperform placebo. Effects on pain could be modest, and individual responses may vary.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
IRCCS Giannina Gaslini
Genova, Genova, 16147, Italy
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