FIBROMYALGIA

This study aims to find a better treatment for fibromyalgia, a condition causing widespread pain and fatigue. Researchers will compare the effectiveness and safety of a new drug called crisugabalin against the commonly used medication pregabalin. The trial will involve over 1,100…

This study is testing whether combining two prescription pain medications (pregabalin and desvenlafaxine) works better than using pregabalin alone for people with fibromyalgia. Researchers want to see if the combination provides stronger pain relief without causing significantly …

This study aims to see if combining two existing medications works better than one alone for managing fibromyalgia pain. It will enroll 750 adults with moderate to severe fibromyalgia who haven't found relief from standard treatments. Researchers will compare pain levels, side ef…

This study is testing whether a non-invasive brain stimulation technique can help control pain in people with fibromyalgia. Researchers will compare brain activity in people with fibromyalgia to healthy volunteers, then test if targeted stimulation can reduce a specific brain pat…

This study is testing if a new combination of two drugs works better for fibromyalgia pain than the current standard drug alone. It will involve 384 adults with moderate to severe fibromyalgia who haven't found enough relief from other non-drug treatments. The goal is to see if t…

This study compares two medications for treating fibromyalgia, a chronic condition causing widespread pain and fatigue. Researchers want to see if a newer drug called mirogabalin works better or has fewer side effects than the commonly used pregabalin. The trial involves 674 adul…

This study is testing whether the medication AXS-14 can help control fibromyalgia symptoms. The trial will involve 620 adults diagnosed with fibromyalgia who will first receive the drug for 12 weeks. Those who respond well will then be randomly assigned to either continue the med…

This study is exploring whether sessions with a shamanic practitioner using drumming music can help reduce pain and other symptoms for people with fibromyalgia. Researchers will work with 25 female participants over 8 weeks, measuring pain levels, heart rate, breathing, and brain…

This early-stage study is investigating whether therapy sessions with the drug MDMA can help reduce the chronic pain of fibromyalgia. Researchers will use special brain scans on 20 participants to see how the treatment might change brain activity and improve the patient-therapist…

This study is testing whether a specific type of hands-on osteopathic therapy can help people with fibromyalgia who also have chronic jaw pain and headaches. Researchers will compare the therapy to usual care in 114 participants. The goal is to see if this approach reduces pain, …

This study is testing whether adding the drug esketamine to standard fibromyalgia treatment provides faster and better pain relief. It will involve 106 adults with fibromyalgia who haven't gotten enough relief from non-drug treatments. The main goal is to see if the combination t…

This study is testing whether real acupuncture can make opioid pain medication work better for people with fibromyalgia. Researchers will compare real acupuncture to fake acupuncture in 45 patients who already take daily opioids. The goal is to see if the real treatment improves …

This study is investigating whether low, non-hallucinogenic doses of psilocybin—the active compound in 'magic mushrooms'—can help reduce pain in people with fibromyalgia. It will involve 35 participants who will receive either a placebo or one of two low doses of psilocybin to se…

This study is testing whether an 8-week program held in a university museum can help women with fibromyalgia. The program combines art appreciation, mindfulness, and gentle movement exercises. Researchers want to see if this unique approach reduces widespread pain and improves da…

This study is testing whether a small, acupuncture-like device placed on the ear can help reduce pain and improve daily function for veterans with fibromyalgia. Researchers will compare the real device to a placebo (sham) device in 240 participants to see if it provides lasting r…

This study is testing whether adding a drug called dexmedetomidine to the standard fibromyalgia medication pregabalin works better for pain relief than pregabalin alone. It will involve 400 adults with moderate to severe fibromyalgia whose pain hasn't been helped enough by non-dr…

This study is testing whether a short, online behavioral therapy program delivered via Zoom can help adults with fibromyalgia, lupus, chronic pelvic pain, or chronic low back pain. The goal is to teach participants strategies to reduce their pain intensity, decrease pain-related …

This study is testing whether a complementary therapy called 'energy healing' can help reduce pain and fatigue for people with fibromyalgia. Researchers will compare real energy healing sessions to fake ones in 25 female participants to see if the real treatment changes brain act…

This study is testing whether an online course can help people with conditions like multiple sclerosis, fibromyalgia, and long COVID feel better. 400 participants will be randomly assigned to either take the course right away or wait. The course teaches about healthy diets, exerc…

This study is testing whether nitrous oxide, commonly known as laughing gas, can help reduce the chronic pain of fibromyalgia. Researchers are comparing two 60-minute sessions of inhaled nitrous oxide to a placebo (oxygen-air mixture) in 50 adults with fibromyalgia. The goal is t…

This study is observing whether wearing a special suit that delivers mild electrical stimulation can help people with conditions like multiple sclerosis, stroke, or cerebral palsy. It aims to see if the suit improves balance, reduces pain, and makes walking easier over time. Abou…

This study is testing whether a combination of brain training exercises and acupuncture can better relieve pain for people with fibromyalgia. Researchers want to see if these activities help a patient's brain and their clinician's brain work in a more synchronized way during trea…

This study is testing whether a 10-week online sleep therapy program can help adults with fibromyalgia who also have trouble sleeping. Researchers want to see if improving sleep can lead to better quality of life, less pain, and more willingness to move. Participants will either …

This study is testing a new, noninvasive treatment that uses focused ultrasound waves to stimulate a specific part of the brain in people with fibromyalgia. The goal is to see if this approach can safely reduce the chronic pain associated with the condition. About 180 adults who …

This study is exploring whether light, self-paced swimming might be a more tolerable way for people with conditions like ME/CFS and Long COVID to move their bodies. It focuses on how being in water might help reduce symptoms like extreme fatigue and post-exertional malaise. Resea…

This study is testing whether a non-invasive brain stimulation technique can reduce chronic pain from nerve damage or fibromyalgia. 100 participants with daily pain will be randomly assigned to receive either real or fake magnetic stimulation sessions over 10 weeks. The main goal…

This study is testing if a walking program that combines outdoor walks with indoor treadmill use, guided by a mobile app, can help women with fibromyalgia. The goal is to see if this approach improves their physical fitness, reduces pain-related fear of movement, and enhances the…

This study is testing whether a mild, non-invasive brain stimulation technique helps people with fibromyalgia manage their pain better when it's added to a standard pain management program. All 68 participants will receive education about pain and do therapeutic exercises, but ha…

This study is testing if adding Shiatsu therapy to regular treatment helps children and teenagers with long-lasting pain feel better and improve their quality of life. About 40 participants, aged 10 to 18, will receive weekly Shiatsu sessions for six weeks while continuing their …

This study is testing a special full-body suit that uses gentle electrical stimulation. It aims to see if wearing the suit is safe and can help reduce pain, muscle stiffness, and improve balance for people with conditions like multiple sclerosis and fibromyalgia. About 15 partici…

This study is testing whether a combination of herbal supplements and vitamin IV (intravenous) therapy can help reduce symptoms for people with conditions like anxiety, chronic pain, fibromyalgia, arthritis, and high blood pressure. It will enroll 25 participants to see if these …

This study is testing if adding special exercise training or gentle nerve stimulation to standard physical therapy helps people with fibromyalgia. Researchers in Poland will compare three groups of 75 adults to see which approach best reduces pain, fatigue, and sleep problems. Th…

This study is testing if a fun, video game-based exercise program using the Nintendo Switch Ring Fit Adventure can help reduce pain and improve balance and mobility for women with fibromyalgia. Researchers will compare it to a standard home exercise program to see which is more e…

This study is testing whether adding immersive virtual reality (VR) to a standard exercise program can better help people with fibromyalgia. 80 participants will be randomly assigned to either do exercises with a VR headset that alters what they see or do the same exercises witho…

This study aims to understand how daily pain, mood, and activities are connected by having 800 participants use a smartphone app called SOMA for four months. The goal is to find patterns that might predict when short-term (acute) pain becomes long-term (chronic) pain. A smaller g…

This study aims to understand how light might help relieve pain by looking at brain activity. Researchers will use MRI scans to see how different colored lights affect brain connections and responses to pain in 30 people with chronic musculoskeletal pain and 30 healthy volunteers…

This study aims to understand how long-term pain conditions like chronic knee pain and fibromyalgia might change the way the brain sends signals to muscles. Researchers will compare adults over 40 with these conditions to pain-free volunteers. Participants will undergo pain sensi…

This study aims to understand how a person's mood, brain inflammation, and body inflammation are connected to pain in veterans with fibromyalgia. Researchers will enroll 60 veterans, some with fibromyalgia and some without, to undergo brain scans, blood tests, and pain assessment…

This study aims to understand if a system giving fake feedback in a virtual reality (VR) environment can change specific brain waves linked to attention control. Researchers will measure brain activity in 35 adults with conditions like rumination or chronic pain while they experi…

This study aims to understand if brain inflammation is linked to chronic pain and fatigue in conditions like fibromyalgia, chronic fatigue syndrome, and multiple sclerosis. Researchers will use a special brain scan to measure inflammation levels in 120 participants, comparing peo…

This study aims to find objective, physical evidence in the brain that explains how an internet-based therapy helps people with fibromyalgia. Researchers will measure pain sensitivity and processing in 50 participants before and after they complete a 10-week online cognitive beha…

This study aims to understand how increased pain sensitivity in the nervous system (central sensitization) relates to memory and thinking problems (cognitive dysfunction) in people with fibromyalgia. Researchers will enroll 100 adults with fibromyalgia to measure their pain sensi…

This study explores whether people with fibromyalgia can learn to control their pain by seeing real-time images of their own brain activity. Participants use MRI brain scans for feedback while trying mental strategies, then receive either therapy or education sessions. The goal i…