New drug mirogabalin takes on pregabalin in fibromyalgia pain showdown

NCT ID NCT07157852

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two drugs, pregabalin and mirogabalin, to see which works better for fibromyalgia pain. About 674 adults with moderate to severe fibromyalgia who haven't tried these medications will take one of the drugs for several weeks. The main goal is to see how many people get at least 50% pain relief, with a focus on finding a safer and more effective option.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
pregabalin and mirogabalin
What this could lead to
If this trial succeeds, it could show that mirogabalin is a more effective or safer option for managing fibromyalgia pain than the current standard drug pregabalin.
What could go wrong
This is an early-stage comparison, not a large phase 3 trial. The drugs may only help a minority of patients, and side effects like dizziness or drowsiness are common. It's not a cure, just a potential improvement in symptom control.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beijing Tiantan Hospital, Beijing, Beijing 100070

    RECRUITING

    Beijing, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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