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Could a questionnaire reveal why endometriosis pain persists?

NCT ID NCT06215937

Knowledge-focused Sponsor: BC Women's Hospital & Health Centre Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 02, 2026 · Last updated Sep 03, 2026 · Updated 1 time

Summary

Endometriosis causes severe pelvic pain, and many people still hurt even after treatment. Researchers suspect the nervous system amplifies pain signals, a process called central sensitization. This study tests whether six patient questionnaires can reliably measure central sensitization by comparing them to objective sensory tests. About 126 people with endometriosis will complete the questionnaires and undergo quantitative sensory testing to see if the two approaches align.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If the questionnaires prove reliable, doctors could use them to spot central sensitization in endometriosis without specialized equipment, guiding more personalized pain care.
What could go wrong
The study only compares questionnaires to sensory tests, not to treatment outcomes. The questionnaires may not fully capture central sensitization, and results may not apply beyond this specific clinic population.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

126 people

The number who actually took part.

Started

May 2024

Finished

Apr 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Individuals who have a new or re-referral appointment at the BC Women's Centre for Pelvic Pain and Endometriosis and who consented to the EPPIC registry (H16-00264).

Ages

19 to 49 years

Sex

Female participants only

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * New or re-referral appointment at the BC Women's Centre for Pelvic Pain and Endometriosis. * Consented to be contacted for future research in the centre data registry (EPPIC NCT02911090; H16-00264). * Surgically confirmed endometriosis, current imaging diagnosis, or current clinically suspected endometriosis diagnosed at the new or re-referral appointment as coded in the registry. * 19 to 49 years old. * Willing and committed to completing six questionnaires about pain. QST specific criteria • Willing and committed to QST testing. Exclusion Criteria: * Currently pregnant or breastfeeding. * Post-menopausal. * Does not speak English - Patients who do not speak English will be excluded to maintain the safety and well-being of the patient, as not understanding the test and process may harm the patient and reduce the validity of the results. We do not have research funding for a translator. Additionally, patients who require a translator are not typically included in the data registry and therefore are unlikely to be in our sample. QST specific criteria * Diabetes or neurological disease predisposing to neuropathic pain. * Previous laparotomy (i.e. large abdominal incision) * Physical trauma (ex., surgery, scaring) to heterotropic QST test site(s) (i.e. deltoid muscle in the shoulder, thenar eminence).

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Conditions

The condition(s) this trial relates to.

endometriosis Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Endometriosis Pain

Contacts and locations

Locations

  • BC Women's Hospital + Health Centre

    Vancouver, British Columbia, V6H 2N9, Canada

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