PREGABALIN

This study is for adults with fibromyalgia whose pain hasn't been helped enough by standard treatments. Researchers want to see if adding esketamine (a rapid-acting painkiller) to usual care can provide better and faster pain relief. About 92 participants will be randomly assigne…

This study compares two medications, pregabalin and mirogabalin, to see which works better for easing pain in people with fibromyalgia, a condition causing widespread pain and fatigue. About 674 adults with moderate to severe fibromyalgia who haven't tried these drugs before will…

This study tests whether melatonin (a natural sleep hormone) works as well as pregabalin (a nerve pain medication) for reducing pain and anxiety after spine surgery. About 105 adults undergoing planned spine surgery will receive one of the two medicines right after the operation.…

This study compares pregabalin alone versus pregabalin plus venlafaxine for fibromyalgia, a condition causing widespread pain and fatigue. Researchers want to see if the combination provides better pain relief without more side effects. The trial will enroll 750 adults with moder…

This study compares pregabalin alone versus pregabalin plus dexmedetomidine for treating fibromyalgia, a condition causing widespread pain and fatigue. Researchers want to see if the combination provides better pain relief without more side effects. The study will enroll 400 adul…

This study tests two medications, pregabalin and a newer drug called crisugabalin, to see which works better for fibromyalgia pain. About 1,100 adults with moderate to severe fibromyalgia will take one of the drugs and report their pain levels. The goal is to find a more effectiv…

This study tests whether adding amantadine or duloxetine to the standard painkiller pregabalin can prevent chronic pain after mastectomy (breast removal surgery). About 150 women undergoing this surgery will be randomly assigned to one of three drug combinations. The goal is to s…

This study compares taking pregabalin alone versus pregabalin combined with desvenlafaxine for fibromyalgia, a condition causing widespread pain and fatigue. Researchers want to see if the combination provides better pain relief without more side effects. The study will involve 3…

This study compares the pain-relieving effects of pregabalin alone versus pregabalin combined with toludesvenlafaxine in people with fibromyalgia. Fibromyalgia causes widespread pain, fatigue, and mood issues, and current treatments often provide only modest relief. The study wil…

This study tests a new drug called Y-4 to see if it can reduce pain from postherpetic neuralgia, a nerve pain that lingers after shingles. About 160 adults in China will take either Y-4 or the standard drug pregabalin for 14 weeks. Researchers will compare pain scores to find out…