Could a nasal spray boost pain relief for fibromyalgia?

NCT ID NCT07230197

Recruiting now Symptom relief Sponsor: Beijing Tiantan Hospital Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether adding a nasal spray drug called dexmedetomidine to the standard medication pregabalin can better relieve pain in people with fibromyalgia. The trial will enroll 400 adults with moderate to severe fibromyalgia who haven't found relief from non-drug treatments. Participants will receive either pregabalin alone or pregabalin plus dexmedetomidine, and their pain levels will be tracked over four weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: pregabalin and dexmedetomidine
What this could lead to: If it works, this could offer a more effective pain relief option for people with fibromyalgia, with fewer side effects than current treatments.
What could go wrong: This is an early-stage trial with no phase designation, so results are uncertain. The combination may not provide significantly better pain relief and could cause unexpected side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for DEXMEDETOMIDINE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

fibromyalgia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DEXMEDETOMIDINE FIBROMYALGIA PREGABALIN

Contacts and locations

Locations

Beijing Tiantan Hospital, Beijing, Beijing 100070
RECRUITING

Beijing, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.