New hope for fibromyalgia? study tests Two-Drug approach for pain

NCT ID NCT07171320

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study compares pregabalin alone versus pregabalin plus desvenlafaxine for treating fibromyalgia, a condition causing widespread pain and fatigue. Researchers will enroll 384 adults with moderate to severe pain that hasn't improved with non-drug treatments. The goal is to see if the combination offers better pain relief without more side effects.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
pregabalin and desvenlafaxine
What this could lead to
If successful, this could offer a more effective pain relief option for people with fibromyalgia who don't get enough help from pregabalin alone.
What could go wrong
This is an early-stage study with no phase designation, so results are uncertain. The combination may not provide significantly better pain relief and could cause more side effects.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Beijing Tiantan Hospital, Beijing, Beijing 100070

    RECRUITING

    Beijing, China

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Other studies related to the condition(s) this trial covers.