New drug combo aims to stop breast surgery pain before it starts

NCT ID NCT07421427

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding amantadine or duloxetine to the standard painkiller pregabalin can prevent chronic pain after mastectomy. About 150 women undergoing breast cancer surgery will be randomly assigned to one of three drug combinations. The goal is to see if these add-ons lower the chance of developing long-term nerve pain and improve quality of life.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Cairo University

    RECRUITING

    Cairo, 12613, Egypt

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