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Teaching the brain about pain before surgery may ease recovery

NCT ID NCT07801586

Symptom relief Sponsor: Foundation University Islamabad Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 03, 2026 · Last updated Sep 04, 2026 · Updated 1 time

Summary

This trial tests whether adding Pain Neuroscience Education to standard pre-operative physiotherapy helps adults aged 35 to 60 recover better after lumbar spine surgery. Participants scheduled for a laminectomy receive either standard exercises alone or the same exercises plus three sessions explaining how the nervous system can amplify pain signals. Researchers measure neuropathic pain and disability before surgery, three weeks after, and three months after to see if understanding pain biology improves outcomes.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Pain Neuroscience Education combined with standard pre-operative physiotherapy
What this could lead to
If it works, this approach could reduce chronic pain and disability after spine surgery, lessening the need for painkillers and long rehabilitation.
What could go wrong
This is a small early trial with 44 participants, so results may not apply broadly. The added education might not improve outcomes beyond standard exercises.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 44 people

The number the study aims to enrol. It can still change while the study runs.

Started

Feb 2026

Expected to finish

Jan 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

35 to 60 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male and female patients * Adults aged 35-60 years. * Scheduled for elective, primary 1- or 2-level lumbar laminectomy/decompression for radiculopathy due to stenosis or herniation. * A pre-surgical waiting period of at least 3 weeks. * Able to understand and provide informed consent in Urdu/English. Exclusion Criteria: * Severe cognitive impairment * Unstable medical conditions * Lower limb or spinal fractures or severe joint deformities * Previous lumbar spine surgery. * Cauda equina syndrome or other surgical emergencies. * Major systemic illness (e.g., uncontrolled cardiovascular disease, cancer) or psychiatric disorder that would limit participation. * Non-ambulatory status prior to surgery * Significant Neural deficit after surgery

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Conditions

The condition(s) this trial relates to.

lumbar spinal stenosis Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Disability Laminectomy Neuroscience Pain Physical therapy

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

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Contacts and locations

Locations

  • Foundation University College of Physical Therapy

    RECRUITING

    Islamabad, 44000, Pakistan

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