FIBROMYALGIA

This study tests the long-term safety and effectiveness of an experimental drug called AXS-14 for people with fibromyalgia, a condition causing widespread pain and fatigue. About 300 adults who previously took part in a related study will receive AXS-14 for 52 weeks. Researchers …

This study tests whether a virtual program called Lin Health can improve daily life for people with fibromyalgia. Researchers at Mayo Clinic will follow 300 adults with fibromyalgia to see if online behavioral health support reduces symptoms and improves function. The goal is to …

This study aimed to see if a one-hour session of inhaled nitrous oxide (laughing gas) could reduce pain in people with fibromyalgia. It was designed for adults aged 18-75 with moderate to severe pain. However, the study was withdrawn before any participants were enrolled, so no r…

This study looks at whether supervised physical activity helps people with fibromyalgia stay active longer than just getting advice. Fibromyalgia causes pain and fatigue, and inactivity can make symptoms worse. The study involves 330 adults who are currently sedentary. Researcher…

This study aimed to see if a device called Sana could improve quality of life for people with fibromyalgia, a condition that causes long-term pain. Researchers planned to compare the active device to a sham (fake) device in adults aged 18 to 65 who had fibromyalgia symptoms for a…

This study is testing a full-spectrum cannabis extract containing CBD and THC in 36 women with fibromyalgia, a condition causing widespread pain, fatigue, and sleep problems. Participants will receive different doses over six months to see if it improves symptoms and quality of l…

This Phase IIa trial tests whether a new drug called ONO-1110 can safely reduce pain in people with fibromyalgia. About 160 Japanese adults will take either the drug or a placebo once daily for 8 weeks. Researchers will measure changes in pain scores and watch for side effects.

This study is testing whether applying peppermint oil to the skin can reduce chronic pain and improve daily function in people with fibromyalgia. Researchers will also look at whether this treatment is cost-effective compared to standard care. About 175 adults with fibromyalgia w…

This study tests whether an 8-week mindfulness yoga program, done mostly at home via video calls, can reduce the impact of fibromyalgia. Sixty-four adults with fibromyalgia are randomly assigned to either the yoga program or standard physiotherapy. The goal is to see if yoga impr…

This study explores whether shining specific colors of light into the eyes can help people with chronic low back pain or fibromyalgia feel less pain. Sixty adults will use a portable light device for 2 hours daily over 5 days. The goal is to see if this approach is practical and …

This study looks at whether slow breathing techniques can help women with fibromyalgia improve their heart rate control and exercise performance. About 159 women will be randomly assigned to breathe slowly (with or without a visual guide) or normally before doing arm curls. Resea…

This Mayo Clinic study tests whether a virtual reality meditation program called TRIPP can reduce the impact of fibromyalgia. Forty adults with fibromyalgia will use either the active VR meditation or a sham (fake) VR experience for two weeks each. Researchers will measure change…

This study looks at whether a single session of mild electrical brain stimulation (tDCS) over the cerebellum can help reduce pain in women with fibromyalgia. About 92 right-handed women aged 18-65 with confirmed fibromyalgia and moderate-to-severe pain will receive the stimulatio…

This study tests whether microcurrent therapy—a very mild electrical stimulation—can reduce pain and improve daily life for people with fibromyalgia. About 50 adults will use a device at home alongside their usual pain care. The goal is to see if this simple, self-administered tr…

This study compares personalized electro-acupuncture and auricular-acupuncture against usual care for treating chronic pain in adults with musculoskeletal pain or fibromyalgia. Participants are split into three groups: two receive different acupuncture methods, and one receives s…

This study tests whether daily exposure to green LED light can reduce chronic pain. 55 adults with conditions like fibromyalgia or nerve pain will use a green or white light device at home for 2 hours each day over 3 months. Researchers will measure changes in pain levels, medica…

This study looks at whether cannabis oil can help reduce pain and improve sleep and quality of life in people with fibromyalgia who have not found relief from other treatments. Researchers will track pain levels, side effects, and how well patients stick to the treatment. The goa…

This study tests a psychological treatment called Pain Reprocessing Therapy (PRT) for people with chronic widespread pain, including fibromyalgia. PRT teaches patients that pain can come from 'stuck' brain patterns and helps them retrain their brain to stop sending false pain ala…

This study investigates factors that may influence cognitive skills—like memory, attention, and problem-solving—in women diagnosed with fibromyalgia. Researchers will assess thinking abilities using a detailed cognitive test and measure how fibromyalgia affects daily life. The go…

This study tests a new imaging method to see if white blood cells enter the brain in people with multiple sclerosis, fibromyalgia, or chronic fatigue syndrome. Participants receive their own white blood cells tagged with a radioactive tracer, then undergo a brain PET/MRI scan. Th…

This study reviewed the medical records of 2500 people who received hyperbaric oxygen therapy (HBOT) for conditions like traumatic brain injury, stroke, fibromyalgia, or age-related decline. Researchers compared computerized thinking and memory tests taken before and after treatm…

This study is testing a Turkish version of a questionnaire that looks at how chronic pain conditions like fibromyalgia and back pain affect sexual function and satisfaction. Researchers will ask 170 people with chronic pain and a stable partner to fill out the survey. The goal is…

This pilot study looks at whether light, self-paced swimming is a tolerable activity for people with ME/CFS and related conditions like Long COVID and fibromyalgia. Participants will swim for 15-30 minutes at their own pace and track symptoms and heart rate variability using an a…

This study looks back at the medical records of about 4 million people who had physical or occupational therapy for muscle and joint problems. Researchers want to see if different ways of giving therapy lead to different results. No new treatments are tested—the goal is to learn …

This study looks at whether stressful or traumatic life events increase the chance of developing fibromyalgia. Researchers will follow 534 adults—some with rheumatic diseases and some healthy—for one year, checking for new fibromyalgia cases. The goal is to better understand how …