Brain zaps may unlock fibromyalgia pain secrets

NCT ID NCT04606095

Ongoing Knowledge-focused Sponsor: University of Michigan Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Aug 11, 2026 · Updated 4 times

Summary

This study looks at how brain networks synchronize in people with fibromyalgia, a condition causing widespread pain. Researchers will use EEG and fMRI to measure brain activity and test a gentle brain stimulation technique called HD-tDCS. The goal is to understand pain processing and see if stimulation can reduce symptoms. 150 adults with fibromyalgia and healthy volunteers will take part.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: high-definition transcranial direct current stimulation (HD-tDCS)
What this could lead to: If successful, this could point toward a new non-invasive brain stimulation treatment for fibromyalgia pain.
What could go wrong: This is an early-stage study focused on understanding brain activity, not a treatment trial. The stimulation approach may not reduce pain in all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

fibromyalgia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

FIBROMYALGIA HEALTHY VOLUNTEERS

Contacts and locations

Locations

University of Michigan

Ann Arbor, Michigan, 48109, United States

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