Can a new drug play nice with common medicines? a trial investigates
NCT ID NCT07766369
First seen Aug 14, 2026 · Last updated Aug 14, 2026
Summary
This early-phase trial in healthy adults asks whether the experimental oral drug E2086 changes how the body processes several common medications, including an antifungal, a seizure drug, a sedative, a cough suppressant, an antidepressant, and birth control pills. Participants receive E2086 alone and with these other drugs to compare blood levels and safety. The goal is to understand potential drug interactions that could affect future dosing recommendations.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- E2086, an experimental oral drug, tested alongside itraconazole, carbamazepine, midazolam, dextromethorphan, bupropion, and combined oral contraceptives
- What this could lead to
- If successful, this could help determine safe dosing of E2086 when taken with other common drugs, supporting its future development as a treatment.
- What could go wrong
- This is an early-phase study in healthy volunteers, not patients, so results may not predict real-world effects. Drug interactions could still occur in ways not captured here.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
PPD Austin Clinical Research Unit (CRU)- Phase 1
Austin, Texas, 78744, United States
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