Magic mushroom compound could ease fibromyalgia pain
NCT ID NCT06368492
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tests whether low doses of psilocybin, the active ingredient in magic mushrooms, can reduce pain in people with fibromyalgia. Thirty-five adults will receive a placebo and two different low doses on separate days. Researchers will measure pain tolerance and self-reported pain to see if psilocybin helps.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
psilocybin
What this could lead to
If it works, this could point toward a new way to manage fibromyalgia pain without strong side effects.
What could go wrong
This is a small, early-phase trial with only 35 people. The low doses may not work, and results might not apply to everyone with fibromyalgia.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Leiden University Medical Center
RECRUITINGLeiden, South Holland, 2333, Netherlands
Contact Email: •••••@•••••
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Maastricht University
RECRUITINGMaastricht, Limburg, 6226AK, Netherlands
Contact Phone: •••-•••-•••• Email: •••••@•••••