Veterans' fibromyalgia pain: can exercise and brain chemistry offer clues?

NCT ID NCT06574165

Recruiting now Knowledge-focused Sponsor: VA Office of Research and Development Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how mood, brain inflammation, and exercise are linked to pain in 60 veterans with fibromyalgia. Participants will do a 6-week supervised walking program and complete pain, mood, and blood tests. The goal is to understand these connections and design a better exercise program for veterans.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Moderate Intensity Continuous Training (aerobic exercise program)
What this could lead to: If successful, this could point toward a personalized exercise program that helps veterans with fibromyalgia better manage chronic pain.
What could go wrong: This is an early-stage, small study (60 participants) focused on understanding links, not testing a treatment. Results may not apply to all fibromyalgia patients.

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Conditions

The condition(s) this trial relates to.

Chronic Pain fibromyalgia Inflammation Motor Activity Neuroinflammatory Diseases

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

FIBROMYALGIA

Contacts and locations

Locations

Birmingham VA Medical Center, Birmingham, AL
RECRUITING

Birmingham, Alabama, 35233-1927, United States

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