Spaulding Rehabilitation Hospital

This early-phase study tests whether MDMA-assisted therapy can reduce pain in 20 adults with fibromyalgia. Participants receive MDMA combined with psychotherapy and undergo brain scans to see how the drug affects pain and the bond between patient and therapist. The goal is to und…

This study is testing a device called SynPhNe that stroke survivors can use at home to retrain their hand function. The goal is to see if it improves hand movement compared to standard care alone. The study will include 40 adults who had a stroke at least 6 months ago and have mo…

This study tests whether wearing ring and wrist sensors and seeing your own movement data on a smartphone can encourage stroke survivors to use their affected arm more during daily activities. Fifty chronic stroke survivors (more than 12 months post-stroke) will wear the sensors …

This study tests whether breathing low oxygen, along with spinal cord stimulation and walking practice, can improve walking for people with chronic spinal cord injury. About 60 adults with some walking ability will take part. The goal is to see if these combined treatments can he…

This study is for adults aged 18–80 with chronic spinal cord injury who can already walk a little. It combines short periods of breathing low oxygen, spinal cord stimulation, and walking practice to see if it helps them walk better. The goal is to improve walking speed and endura…

This study is testing whether a slow, resistive yogic breathing technique called Ujjayi can improve breathing, lung function, and sleep in people with spinal cord injuries. Twenty adults aged 18 to 60 who use wheelchairs will practice Ujjayi breathing for six weeks. Before and af…

This study tests whether a painless brain stimulation technique (tDCS plus ultrasound) can reduce chronic pain in people with carpal tunnel syndrome. About 95 adults with long-term wrist pain will receive either real or fake (sham) stimulation to see if it lowers their pain score…

This study is testing whether extracorporeal shockwave therapy (ESWT) can reduce pain and improve function in athletes who developed knee osteoarthritis after ACL reconstruction. Researchers will treat 70 participants with a device that delivers pressure waves to the knee. The go…

This study tests a wrist-worn sensor system called StrokeWear that gives feedback and encourages stroke survivors to use their weaker arm more during daily activities. 88 people who had a stroke 1-6 months ago will either use the system plus a home exercise plan, or just the exer…

This Phase 2 trial tests a wrist-worn sensor system called StrokeWear, combined with goal-setting and daily action planning, to encourage stroke survivors to use their weaker arm more during everyday activities. The study enrolls 32 chronic stroke survivors who will either use th…

This study tests whether combining a nerve-stimulating device (placed on the ear) with behavioral therapy can reduce stomach pain and anxiety in people with functional dyspepsia, a condition where the stomach feels upset without a clear cause. Researchers will track symptoms and …

This study tests whether combining cognitive training with electroacupuncture can reduce pain in people with fibromyalgia. Researchers will use brain scans to see if the treatment improves how patient and clinician brains sync up. The trial enrolls 100 adults with fibromyalgia an…

This study tests whether a portable brain stimulation device, used at home along with sensory training, can reduce phantom limb pain in amputees. About 290 participants will either receive the active treatment or continue their usual care. The goal is to see if this approach work…

This study tests a new camera tool that watches how stroke survivors move their arms during robot-assisted therapy and gives feedback. The goal is to see if group therapy sessions (up to 3 people) work as well as one-on-one sessions. About 42 adults who had a stroke 6 months to 6…

This study tests whether breathing low oxygen for short periods (called intermittent hypoxia) can improve walking and strength in people with chronic spinal cord injury. Researchers want to understand how this affects the nervous system. The trial involves 44 participants who wil…

This observational study looks at how the brains of romantic partners communicate compared to strangers. Using a technique called hyperscanning, researchers will record brain activity from two people at the same time, both in person and remotely. The goal is to understand what fa…

This study looks at how the Q-Collar, a device already cleared by the FDA, changes brain blood flow in healthy adults during rest and exercise. Twenty participants aged 18 to 30 will do tasks like standing up quickly, breathing against resistance, and biking while their brain blo…

This study looks at whether placebos—given openly or hidden—can change brain activity and improve movement in people who had a stroke at least six months ago. Researchers will use brain scans and motor tests to measure effects. The goal is to understand how placebos work in the b…