Spaulding Rehabilitation Hospital
Clinical trials sponsored by Spaulding Rehabilitation Hospital, explained in plain language.
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Can a breathing machine or a drug boost exercise benefits for spinal cord injury?
Disease control OngoingThis study tests whether adding non-invasive ventilation (a breathing machine) or the drug Buspar to a special rowing exercise program can improve heart and lung fitness in people with high-level spinal cord injury. Seventy participants will exercise for 6 months while receiving …
Phase: PHASE2 • Sponsor: Spaulding Rehabilitation Hospital • Aim: Disease control
Last updated Jun 27, 2026 09:11 UTC
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Breathing low oxygen may reboot walking after spinal injury
Disease control OngoingThis study tests whether short, mild low-oxygen breathing sessions can improve walking and leg strength in people with a recent spinal cord injury. Over 10 sessions, participants breathe either low-oxygen air or normal air through a mask. The goal is to see if this simple approac…
Phase: NA • Sponsor: Spaulding Rehabilitation Hospital • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC
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New smart socket aims to get amputees moving again
Symptom relief OngoingThis study tests a new type of prosthetic socket and liner designed to better distribute pressure on the remaining limb. Combined with an exercise program, the goal is to help people who lost a leg due to diabetes walk more and improve their health. About 38 participants who alre…
Phase: PHASE2 • Sponsor: Spaulding Rehabilitation Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:24 UTC
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Can a treadmill plus brain games help stroke patients walk again?
Symptom relief OngoingThis study tests a device called GaitBetter that combines treadmill walking with cognitive training (like thinking tasks) to help stroke survivors improve their walking and balance. About 76 people who had a stroke (either within 8 weeks or more than 6 months ago) will use the de…
Phase: NA • Sponsor: Spaulding Rehabilitation Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:03 UTC
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Breathing trick boosts walking after spinal injury
Symptom relief OngoingThis study tests whether brief periods of breathing low oxygen can improve leg strength and walking in people with chronic spinal cord injury. Thirty adults with incomplete spinal cord injury will inhale low oxygen for short sessions over time. Researchers will measure walking en…
Phase: NA • Sponsor: Spaulding Rehabilitation Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 11:03 UTC
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Brain zaps and ultrasound may help Parkinson's patients stay steady
Symptom relief OngoingThis study tests whether combining two types of brain stimulation (tDCS and TUS) with physical therapy can improve balance in people with Parkinson's disease. Forty participants will receive either real or sham stimulation during therapy sessions over two weeks. The goal is to se…
Phase: NA • Sponsor: Spaulding Rehabilitation Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 09:09 UTC
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Placebo power: cutting opioids without extra pain
Symptom relief OngoingThis study tests a method called conditioning open-label placebo (COLP) to help patients with spinal cord injury, multiple injuries, or burns use fewer opioids while still getting the same pain relief. About 66 adults in intensive rehab will receive a placebo alongside their regu…
Phase: NA • Sponsor: Spaulding Rehabilitation Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 07:55 UTC
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Zapping the brain to quiet knee pain: new study tests two non-invasive techniques
Symptom relief OngoingThis study tested whether two types of gentle brain stimulation (tDCS and TUS) can reduce pain and improve daily function in people with chronic knee osteoarthritis. 64 adults with persistent knee pain received either real or sham stimulation. Researchers measured changes in pain…
Sponsor: Spaulding Rehabilitation Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 07:52 UTC
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Zapping the brain to zap back pain: new study tests Non-Invasive relief
Symptom relief OngoingThis study tests whether two types of gentle brain stimulation—tDCS and TUS—can reduce pain and improve daily function in people with chronic low back pain. Researchers will compare active stimulation to a sham (fake) treatment in 40 adults aged 18-85 who have had persistent back…
Sponsor: Spaulding Rehabilitation Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 07:52 UTC
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New combo therapy aims to quiet phantom limb pain
Symptom relief OngoingThis study tests whether combining mirror therapy with a gentle brain stimulation technique (tDCS) can reduce phantom limb pain in people with leg amputations. 132 adults with chronic pain will be assigned to different treatment groups to see which approach works best. The goal i…
Phase: NA • Sponsor: Spaulding Rehabilitation Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC